Anti-Inflammatory and Tau Phosphorylation–Inhibitory Effects of Eupatin

por Chou, Ching-Hsuan, Hsu, Kai-Cheng, Lin, Tony Eight, Yang, Chia-Ron
Publicado 2020

The role of ubiquitin-specific peptidases in cancer progression

por Young, Ming-Jer, Hsu, Kai-Cheng, Lin, Tony Eight, Chang, Wen-Chang, Hung, Jan-Jong
Publicado 2019

Investigation of Anti-Tumor Effects of an MLK1 Inhibitor in Prostate and Pancreatic Cancers

por Fan, Yu-Ching, Hsu, Kai-Cheng, Lin, Tony-Eight, Zechner, Dietmar, Hsu, Sung-Po, Tsai, Yuan-Chin
Publicado 2021

Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

por Lin, Chao-Feng, Hsu, Kai-Cheng, HuangFu, Wei-Chun, Lin, Tony Eight, Huang, Han-Li, Pan, Shiow-Lin
Publicado 2020

Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol

por Lee, Szu, Chao, Min-Wu, Wu, Yi-Wen, Hsu, Chia-Min, Lin, Tony Eight, Hsu, Kai-Cheng, Pan, Shiow-Lin, Lee, Hsueh-Yun
Publicado 2023

Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach

por Hsu, Kai-Cheng, Liu, Chang-Yi, Lin, Tony Eight, Hsieh, Jui-Hua, Sung, Tzu-Ying, Tseng, Hui-Ju, Yang, Jinn-Moon, Huang, Wei-Jan
Publicado 2017

Urolithin A exhibits a neuroprotective effect against Alzheimer’s disease by inhibiting DYRK1A activity

por Tu, Huang-Ju, Su, Chih-Jou, Peng, Chao-Shiang, Lin, Tony Eight, HuangFu, Wei-Chun, Hsu, Kai-Cheng, Hwang, Tsong-Long, Pan, Shiow-Lin
Publicado 2023

Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment

por Lin, Tony Eight, Yang, Chia-Ron, Chou, Ching-Hsuan, Hsu, Jui-Yi, Chao, Min-Wu, Sung, Tzu-Ying, Hsieh, Jui-Hua, Huang, Wei-Jan, Hsu, Kai-Cheng
Publicado 2022

13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity against Oral Cancer Cells through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Con...

por Liu, Yi-Chang, Peng, Bo-Rong, Hsu, Kai-Cheng, El-Shazly, Mohamed, Shih, Shou-Ping, Lin, Tony Eight, Kuo, Fu-Wen, Chou, Yi-Cheng, Lin, Hung-Yu, Lu, Mei-Chin
Publicado 2020

Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors

por Lin, Tony Eight, Sung, Li-Chin, Chao, Min-Wu, Li, Min, Zheng, Jia-Huei, Sung, Tzu-Ying, Hsieh, Jui-Hua, Yang, Chia-Ron, Lee, Hsueh-Yun, Cho, Er-Chieh, Hsu, Kai-Cheng
Publicado 2021

A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

por Lin, Tony Eight, HuangFu, Wei-Chun, Chao, Min-Wu, Sung, Tzu-Ying, Chang, Chao-Di, Chen, Yi-Ying, Hsieh, Jui-Hua, Tu, Huang-Ju, Huang, Han-Li, Pan, Shiow-Lin, Hsu, Kai-Cheng
Publicado 2018

A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors

por Hsu, Kai-Cheng, HuangFu, Wei-Chun, Lin, Tony Eight, Chao, Min-Wu, Sung, Tzu-Ying, Chen, Yi-Ying, Pan, Shiow-Lin, Lee, Jih-Chin, Tzou, Shey-Cherng, Sun, Chung-Ming, Yang, Jinn-Moon
Publicado 2020

In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer

por Chang, Chao-Di, Chao, Min-Wu, Lee, Hsueh-Yun, Liu, Yi-Ting, Tu, Huang-Ju, Lien, Ssu-Ting, Lin, Tony Eight, Sung, Tzu-Ying, Yen, Shih-Chung, Huang, Sing-Han, Hsu, Kai-Cheng, Pan, Shiow-Lin
Publicado 2023

Synthesis and biological evaluation of C-4 substituted phenoxazine-bearing hydroxamic acids with potent class II histone deacetylase inhibitory activities

por Chu, Jung-Chun, Tseng, Hui-Ju, Lee, Sung-Bau, Hsu, Kai-Cheng, Hsin, Ling-Wei, Liang, Ru-Hao, Lin, Tony Eight, Gao, Nain-Chu, Chen, Liang-Chieh, Lu, Wan-Hsun, Wang, Andrew H.-J, Huang, Wei-Jan
Publicado 2023

Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

por Chao, Min-Wu, Lin, Tony Eight, HuangFu, Wei-Chun, Chang, Chao-Di, Tu, Huang-Ju, Chen, Liang-Chieh, Yen, Shih-Chung, Sung, Tzu-Ying, Huang, Wei-Jan, Yang, Chia-Ron, Pan, Shiow-Lin, Hsu, Kai-Cheng
Publicado 2020