One‐step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock‐in mice

por Lin, Ying‐Cing, Pecetta, Simone, Steichen, Jon M, Kratochvil, Sven, Melzi, Eleonora, Arnold, Johan, Dougan, Stephanie K, Wu, Lin, Kirsch, Kathrin H, Nair, Usha, Schief, William R, Batista, Facundo D
Publicado 2018

Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors

por Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole, Adachi, Yumiko, Tingle, Ryan, Wu, Lin, Crotty, Shane, Kirsch, Kathrin H, Nair, Usha, Schief, William R, Batista, Facundo D
Publicado 2020

Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice

por Melzi, Eleonora, Willis, Jordan R., Ma, Krystal M., Lin, Ying-Cing, Kratochvil, Sven, Berndsen, Zachary T., Landais, Elise A., Kalyuzhniy, Oleksandr, Nair, Usha, Warner, John, Steichen, Jon M., Kalyuzhniy, Anton, Le, Amber, Pecetta, Simone, Perez, Manfredo, Kirsch, Kathrin, Weldon, Stephanie R., Falcone, Samantha, Himansu, Sunny, Carfi, Andrea, Sok, Devin, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Publicado 2022

Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

por Tas, Jeroen M.J., Koo, Ja-Hyun, Lin, Ying-Cing, Xie, Zhenfei, Steichen, Jon M., Jackson, Abigail M., Hauser, Blake M., Wang, Xuesong, Cottrell, Christopher A., Torres, Jonathan L., Warner, John E., Kirsch, Kathrin H., Weldon, Stephanie R., Groschel, Bettina, Nogal, Bartek, Ozorowski, Gabriel, Bangaru, Sandhya, Phelps, Nicole, Adachi, Yumiko, Eskandarzadeh, Saman, Kubitz, Michael, Burton, Dennis R., Lingwood, Daniel, Schmidt, Aaron G., Nair, Usha, Ward, Andrew B., Schief, William R., Batista, Facundo D.
Publicado 2022