SAINT: Probabilistic Scoring of Affinity Purification - Mass Spectrometry Data

por Choi, Hyungwon, Larsen, Brett, Lin, Zhen-Yuan, Breitkreutz, Ashton, Mellacheruvu, Dattatreya, Fermin, Damian, Qin, Zhaohui S., Tyers, Mike, Gingras, Anne-Claude, Nesvizhskii, Alexey I.
Publicado 2010

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

por Janer, Alexandre, Morris, Jordan L, Krols, Michiel, Antonicka, Hana, Aaltonen, Mari J, Lin, Zhen-Yuan, Anand, Hanish, Gingras, Anne-Claude, Prudent, Julien, Shoubridge, Eric A
Publicado 2023

TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex

por Merritt, Nicole, Garcia, Keith, Rajendran, Dushyandi, Lin, Zhen-Yuan, Zhang, Xiaomeng, Mitchell, Katrina A, Borcherding, Nicholas, Fullenkamp, Colleen, Chimenti, Michael S, Gingras, Anne-Claude, Harvey, Kieran F, Tanas, Munir R
Publicado 2021

Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fung...

por O’Meara, Teresa R., O’Meara, Matthew J., Polvi, Elizabeth J., Pourhaghighi, M. Reza, Liston, Sean D., Lin, Zhen-Yuan, Veri, Amanda O., Emili, Andrew, Gingras, Anne-Claude, Cowen, Leah E.
Publicado 2019

Mapping differential interactomes by affinity purification coupled with data independent mass spectrometry acquisition

por Lambert, Jean-Philippe, Ivosev, Gordana, Couzens, Amber L., Larsen, Brett, Taipale, Mikko, Lin, Zhen-Yuan, Zhong, Quan, Lindquist, Susan, Vidal, Marc, Aebersold, Ruedi, Pawson, Tony, Bonner, Ron, Tate, Stephen, Gingras, Anne-Claude
Publicado 2013

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

por Janer, Alexandre, Prudent, Julien, Paupe, Vincent, Fahiminiya, Somayyeh, Majewski, Jacek, Sgarioto, Nicolas, Des Rosiers, Christine, Forest, Anik, Lin, Zhen‐Yuan, Gingras, Anne‐Claude, Mitchell, Grant, McBride, Heidi M, Shoubridge, Eric A
Publicado 2016

ProHits: an integrated software platform for mass spectrometry-based interaction proteomics

por Liu, Guomin, Zhang, Jianping, Larsen, Brett, Stark, Chris, Breitkreutz, Ashton, Lin, Zhen-Yuan, Breitkreutz, Bobby-Joe, Ding, Yongmei, Colwill, Karen, Pasculescu, Adrian, Pawson, Tony, Wrana, Jeffrey L., Nesvizhskii, Alexey I., Raught, Brian, Tyers, Mike, Gingras, Anne-Claude
Publicado 2010

Functional divergence of a global regulatory complex governing fungal filamentation

por Polvi, Elizabeth J., Veri, Amanda O., Liu, Zhongle, Hossain, Saif, Hyde, Sabrina, Kim, Sang Hu, Tebbji, Faiza, Sellam, Adnane, Todd, Robert T., Xie, Jinglin L., Lin, Zhen-Yuan, Wong, Cassandra J., Shapiro, Rebecca S., Whiteway, Malcolm, Robbins, Nicole, Gingras, Anne-Claude, Selmecki, Anna, Cowen, Leah E.
Publicado 2019

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains

por Lambert, Jean-Philippe, Picaud, Sarah, Fujisawa, Takao, Hou, Huayun, Savitsky, Pavel, Uusküla-Reimand, Liis, Gupta, Gagan D., Abdouni, Hala, Lin, Zhen-Yuan, Tucholska, Monika, Knight, James D.R., Gonzalez-Badillo, Beatriz, St-Denis, Nicole, Newman, Joseph A., Stucki, Manuel, Pelletier, Laurence, Bandeira, Nuno, Wilson, Michael D., Filippakopoulos, Panagis, Gingras, Anne-Claude
Publicado 2019

Pervasive mislocalization of pathogenic coding variants underlying human disorders

por Lacoste, Jessica, Haghighi, Marzieh, Haider, Shahan, Lin, Zhen-Yuan, Segal, Dmitri, Reno, Chloe, Qian, Wesley Wei, Xiong, Xueting, Shafqat-Abbasi, Hamdah, Ryder, Pearl. V., Senft, Rebecca, Cimini, Beth A., Roth, Frederick P., Calderwood, Michael, Hill, David, Vidal, Marc, Yi, S. Stephen, Sahni, Nidhi, Peng, Jian, Gingras, Anne-Claude, Singh, Shantanu, Carpenter, Anne E., Taipale, Mikko
Publicado 2023

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism

por Aregger, Michael, Lawson, Keith A., Billmann, Maximillian, Costanzo, Michael, Tong, Amy H. Y., Chan, Katherine, Rahman, Mahfuzur, Brown, Kevin R., Ross, Catherine, Usaj, Matej, Nedyalkova, Lucy, Sizova, Olga, Habsid, Andrea, Pawling, Judy, Lin, Zhen-Yuan, Abdouni, Hala, Wong, Cassandra J., Weiss, Alexander, Mero, Patricia, Dennis, James W., Gingras, Anne-Claude, Myers, Chad L., Andrews, Brenda J., Boone, Charles, Moffat, Jason
Publicado 2020

Leveraging machine learning essentiality predictions and chemogenomic interactions to identify antifungal targets

por Fu, Ci, Zhang, Xiang, Veri, Amanda O., Iyer, Kali R., Lash, Emma, Xue, Alice, Yan, Huijuan, Revie, Nicole M., Wong, Cassandra, Lin, Zhen-Yuan, Polvi, Elizabeth J., Liston, Sean D., VanderSluis, Benjamin, Hou, Jing, Yashiroda, Yoko, Gingras, Anne-Claude, Boone, Charles, O’Meara, Teresa R., O’Meara, Matthew J., Noble, Suzanne, Robbins, Nicole, Myers, Chad L., Cowen, Leah E.
Publicado 2021

The Shieldin complex mediates 53BP1-dependent DNA repair

por Noordermeer, Sylvie M., Adam, Salomé, Setiaputra, Dheva, Barazas, Marco, Pettitt, Stephen J., Ling, Alexanda K., Olivieri, Michele, Álvarez-Quilón, Alejandro, Moatti, Nathalie, Zimmermann, Michal, Annunziato, Stefano, Krastev, Dragomir B., Song, Feifei, Brandsma, Inger, Frankum, Jessica, Brough, Rachel, Sherker, Alana, Landry, Sébastien, Szilard, Rachel K., Munro, Meagan M., McEwan, Andrea, Goullet de Rugy, Théo, Lin, Zhen-Yuan, Hart, Traver, Moffat, Jason, Gingras, Anne-Claude, Martin, Alberto, van Attikum, Haico, Jonkers, Jos, Lord, Christopher J., Rottenberg, Sven, Durocher, Daniel
Publicado 2018

The CRAPome: a Contaminant Repository for Affinity Purification Mass Spectrometry Data

por Mellacheruvu, Dattatreya, Wright, Zachary, Couzens, Amber L., Lambert, Jean-Philippe, St-Denis, Nicole, Li, Tuo, Miteva, Yana V., Hauri, Simon, Sardiu, Mihaela E., Low, Teck Yew, Halim, Vincentius A., Bagshaw, Richard D., Hubner, Nina C., al-Hakim, Abdallah, Bouchard, Annie, Faubert, Denis, Fermin, Damian, Dunham, Wade H., Goudreault, Marilyn, Lin, Zhen-Yuan, Badillo, Beatriz Gonzalez, Pawson, Tony, Durocher, Daniel, Coulombe, Benoit, Aebersold, Ruedi, Superti-Furga, Giulio, Colinge, Jacques, Heck, Albert J. R., Choi, Hyungwon, Gstaiger, Matthias, Mohammed, Shabaz, Cristea, Ileana M., Bennett, Keiryn L., Washburn, Mike P., Raught, Brian, Ewing, Rob M., Gingras, Anne-Claude, Nesvizhskii, Alexey I.
Publicado 2013