Development of a quantitative relationship between CAR-affinity, antigen abundance, tumor cell depletion and CAR-T cell expansion using a multiscale systems PK-PD model

por Singh, Aman P., Zheng, Xirong, Lin-Schmidt, Xiefan, Chen, Wenbo, Carpenter, Thomas J., Zong, Alice, Wang, Weirong, Heald, Donald L.
Publicado 2019

Discovery and characterization of single-domain antibodies for polymeric Ig receptor-mediated mucosal delivery of biologics

por Maruthachalam, Bharathikumar Vellalore, Zwolak, Adam, Lin-Schmidt, Xiefan, Keough, Edward, Tamot, Ninkka, Venkataramani, Sathya, Geist, Brian, Singh, Sanjaya, Ganesan, Rajkumar
Publicado 2020

A long‐acting GDF15 analog causes robust, sustained weight loss and reduction of food intake in an obese nonhuman primate model

por Zheng, Songmao, Polidori, David, Wang, Yuanping, Geist, Brian, Lin‐Schmidt, Xiefan, Furman, Jennifer L., Nelson, Serena, Nawrocki, Andrea R., Hinke, Simon A.
Publicado 2023