Training the Future Leaders in Personalized Medicine

por Mason-Suares, Heather, Sweetser, David A., Lindeman, Neal I., Morton, Cynthia C.
Publicado 2016

POLE-mutated clear cell cervical cancer associated with in-utero diethylstilbestrol exposure

por Lee, Elizabeth K., Lindeman, Neal I., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A.
Publicado 2019

Refractory myeloid sarcoma with a FIP1L1-PDGFRA rearrangement detected by clinical high throughput somatic sequencing

por Mandelker, Diana, Dal Cin, Paola, Jacene, Heather A., Armand, Philippe, Stone, Richard M., Lindeman, Neal I.
Publicado 2015

Targeted Next-Generation Sequencing Reveals Clinically Actionable BRAF and ESR1 Mutations in Low-Grade Serous Ovarian Carcinoma

por Stover, Elizabeth H., Feltmate, Colleen, Berkowitz, Ross S., Lindeman, Neal I., Matulonis, Ursula A., Konstantinopoulos, Panagiotis A.
Publicado 2018

Practical Considerations Relating to Routine Clinical Biomarker Testing for Non–small Cell Lung Cancer: Focus on Testing for RET Fusions

por Herbst, Roy S., Aisner, Dara L., Sonett, Joshua R., Turk, Andrew T., Weintraub, Joshua L., Lindeman, Neal I.
Publicado 2021

Novel Pathogenic Germline Variant of the Adenomatous Polyposis Coli (APC) Gene, p.S2627Gfs*12 Identified in a Mild Phenotype of APC-Associated Polyposis: A Case Report

por Koeller, Diane R., Schwartz, Alison, Manning, Danielle K., Dong, Fei, Lindeman, Neal I., Garber, Judy E., Ghazani, Arezou A.
Publicado 2020

Rapid next-generation sequencing aids in diagnosis of transient abnormal myelopoiesis in a phenotypically normal newborn

por Aziz-Bose, Rahela, Wachter, Franziska, Chiarle, Roberto, Lindeman, Neal I., Kim, Annette S., Degar, Barbara A., Davies, Kimberly, Pikman, Yana
Publicado 2022

Germline Testing Data Validate Inferences of Mutational Status for Variants Detected From Tumor-Only Sequencing

por Jalloul, Nahed, Gomy, Israel, Stokes, Samantha, Gusev, Alexander, Johnson, Bruce E., Lindeman, Neal I., Macconaill, Laura, Ganesan, Shridar, Garber, Judy E., Khiabanian, Hossein
Publicado 2021

Somatic mutations in CDH1 and CTNNB1 in primary carcinomas at 13 anatomic sites

por Busch, Evan L., Hornick, Jason L., Umeton, Renato, Albayrak, Adem, Lindeman, Neal I., MacConaill, Laura E., Garcia, Elizabeth P., Ducar, Matthew, Rebbeck, Timothy R.
Publicado 2017

Phase I Trial of a Tablet Formulation of Pilaralisib, a Pan‐Class I PI3K Inhibitor, in Patients with Advanced Solid Tumors

por Edelman, Gerald, Rodon, Jordi, Lager, Joanne, Castell, Christelle, Jiang, Jason, Van Allen, Eliezer M., Wagle, Nikhil, Lindeman, Neal I., Sholl, Lynette M., Shapiro, Geoffrey I.
Publicado 2018

An optimized protocol for evaluating pathogenicity of VHL germline variants in patients suspected with von Hippel-Lindau syndrome: Using somatic genome to inform the role of germli...

por Koeller, Diane R., Manning, Danielle K., Schwartz, Alison, Chittenden, Anu, Hayes, Connor P., Abraamyan, Feruza, Rana, Huma Q., Lindeman, Neal I., Garber, Judy E., Ghazani, Arezou A.
Publicado 2022

Myeloid neoplasm demonstrating a STAT5B-RARA rearrangement and genetic alterations associated with all-trans retinoic acid resistance identified by a custom next-generation sequenc...

por Kluk, Michael J., Abo, Ryan P., Brown, Ronald D., Kuo, Frank C., Dal Cin, Paola, Pozdnyakova, Olga, Morgan, Elizabeth A., Lindeman, Neal I., DeAngelo, Daniel J., Aster, Jon C.
Publicado 2015

Twists and turns from “tumor in tumor” profiling: surveillance of chronic lymphocytic leukemia (CLL) leads to detection of a lung adenocarcinoma, whose genomic characterization alt...

por Terraf, Panieh, Sholl, Lynette M., Davids, Matthew S., Awad, Mark M., Garcia, Elizabeth P., MacConaill, Laura E., Dal Cin, Paola, Kim, Annette, Lindeman, Neal I., Stachler, Matthew, Hwang, David H., Dubuc, Adrian M.
Publicado 2021

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers

por Abo, Ryan P., Ducar, Matthew, Garcia, Elizabeth P., Thorner, Aaron R., Rojas-Rudilla, Vanesa, Lin, Ling, Sholl, Lynette M., Hahn, William C., Meyerson, Matthew, Lindeman, Neal I., Van Hummelen, Paul, MacConaill, Laura E.
Publicado 2015

Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

por Tsai, Harrison K., Brackett, Diane G., Szeto, David, Frazier, Ryan, MacLeay, Allison, Davineni, Phani, Manning, Danielle K., Garcia, Elizabeth, Lindeman, Neal I., Le, Long P., Lennerz, Jochen K., Gibson, Christopher J., Lindsley, R. Coleman, Kim, Annette S., Nardi, Valentina
Publicado 2020

Targeted next-generation sequencing reveals high frequency of mutations in epigenetic regulators across treatment-naïve patient melanomas

por Lee, Jonathan J., Sholl, Lynette M., Lindeman, Neal I., Granter, Scott R., Laga, Alvaro C., Shivdasani, Priyanka, Chin, Gary, Luke, Jason J., Ott, Patrick A., Hodi, F. Stephen, Mihm, Martin C., Lin, Jennifer Y., Werchniak, Andrew E., Haynes, Harley A., Bailey, Nancy, Liu, Robert, Murphy, George F., Lian, Christine G.
Publicado 2015

Clinical multiplexed exome sequencing distinguishes adult oligodendroglial neoplasms from astrocytic and mixed lineage gliomas

por Cryan, Jane B., Haidar, Sam, Ramkissoon, Lori A., Bi, Wenya Linda, Knoff, David S., Schultz, Nikolaus, Abedalthagafi, Malak, Brown, Loreal, Wen, Patrick Y., Reardon, David A., Dunn, Ian F., Folkerth, Rebecca D., Santagata, Sandro, Lindeman, Neal I., Ligon, Azra H., Beroukhim, Rameen, Hornick, Jason L., Alexander, Brian M., Ligon, Keith L., Ramkissoon, Shakti H.
Publicado 2014

A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma

por Nassar, Amin H., Mouw, Kent W., Jegede, Opeyemi, Shinagare, Atul B., Kim, Jaegil, Liu, Chia-Jen, Pomerantz, Mark, Harshman, Lauren C., Van Allen, Eliezer M., Wei, Xiao X., McGregor, Bradley, Choudhury, Atish D., Preston, Mark A., Dong, Fei, Signoretti, Sabina, Lindeman, Neal I., Bellmunt, Joaquim, Choueiri, Toni K., Sonpavde, Guru, Kwiatkowski, David J.
Publicado 2019

Identification and Management of Pathogenic Variants in BRCA1, BRCA2, and PALB2 in a Tumor-Only Genomic Testing Program

por Bychkovsky, Brittany L., Li, Tianyu, Sotelo, Jilliane, Tayob, Nabihah, Mercado, Joanna, Gomy, Israel, Chittenden, Anu, Kane, Sarah, Stokes, Samantha, Hughes, Melissa E., Kim, Ji Seok, Umeton, Renato, Awad, Mark M., Konstantinopoulos, Panagiotis A., Yurgelun, Matthew B., Wolpin, Brian M., Taplin, Mary-Ellen, Newmark, Randall E., Johnson, Bruce E., Lindeman, Neal I., MacConaill, Laura E., Garber, Judy E., Lin, Nancy U.
Publicado 2022

Rare FGFR Oncogenic Alterations in Sequenced Pediatric Solid and Brain Tumors Suggest FGFR Is a Relevant Molecular Target in Childhood Cancer

por Lazo De La Vega, Lorena, Comeau, Hannah, Sallan, Sarah, Al-Ibraheemi, Alyaa, Gupta, Hersh, Li, Yvonne Y., Tsai, Harrison K., Kang, Wenjun, Ward, Abigail, Church, Alanna J., Kim, AeRang, Pinto, Navin R., Macy, Margaret E., Maese, Luke D., Sabnis, Amit J., Cherniack, Andrew D., Lindeman, Neal I., Anderson, Megan E., Cooney, Tabitha M., Yeo, Kee Kiat, Reaman, Gregory H., DuBois, Steven G., Collins, Natalie B., Johnson, Bruce E., Janeway, Katherine A., Forrest, Suzanne J.
Publicado 2022