STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses

por Scott, Ori, Lindsay, Kyle, Erwood, Steven, Mollica, Antonio, Roifman, Chaim M., Cohn, Ronald D., Ivakine, Evgueni A.
Publicado 2021

Prevention of early-onset cardiomyopathy in Dmd exon 52–54 deletion mice by CRISPR-Cas9-mediated exon skipping

por Rok, Matthew, Wong, Tatianna Wai Ying, Maino, Eleonora, Ahmed, Abdalla, Yang, Grace, Hyatt, Elzbieta, Lindsay, Kyle, Fatehi, Sina, Marks, Ryan, Delgado-Olguín, Paul, Ivakine, Evgueni A., Cohn, Ronald D.
Publicado 2023

A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy

por Wong, Tatianna Wai Ying, Ahmed, Abdalla, Yang, Grace, Maino, Eleonora, Steiman, Sydney, Hyatt, Elzbieta, Chan, Parry, Lindsay, Kyle, Wong, Nicole, Golebiowski, Diane, Schneider, Joel, Delgado-Olguín, Paul, Ivakine, Evgueni A., Cohn, Ronald D.
Publicado 2020

An efficient and cost-effective purification protocol for Staphylococcus aureus Cas9 nuclease

por Teng, Allen C.T., Tavassoli, Marjan, Shrestha, Suja, Marks, Ryan M., McFadden, Meghan J., Evagelou, Sonia L., Lindsay, Kyle, Vandenbelt, Ava, Li, Wenping, Ivakine, Evgueni, Cohn, Ronald, Santerre, J. Paul, Gramolini, Anthony O.
Publicado 2022

Targeted genome editing in vivo corrects a Dmd duplication restoring wild‐type dystrophin expression

por Maino, Eleonora, Wojtal, Daria, Evagelou, Sonia L, Farheen, Aiman, Wong, Tatianna W Y, Lindsay, Kyle, Scott, Ori, Rizvi, Samar Z, Hyatt, Elzbieta, Rok, Matthew, Visuvanathan, Shagana, Chiodo, Amanda, Schneeweiss, Michelle, Ivakine, Evgueni A, Cohn, Ronald D
Publicado 2021