Antibody Focusing to Conserved Sites of Vulnerability: The Immunological Pathways for ‘Universal’ Influenza Vaccines

por Sangesland, Maya, Lingwood, Daniel
Publicado 2021

Public Immunity: Evolutionary Spandrels for Pathway-Amplifying Protective Antibodies

por Sangesland, Maya, Lingwood, Daniel
Publicado 2021

Modeling and Manipulating Antibody Response Against Influenza and Coronavirus Spike Proteins and Exploring their Role in Directing Spike Evolution

por Amitai, Assaf, Sangesland, Maya, Lingwood, Daniel, Chakraborty, Arup K.
Publicado 2021

Humoral responses to the SARS-CoV-2 spike and receptor binding domain in context of pre-existing immunity confer broad sarbecovirus neutralization

por Hauser, Blake M., Sangesland, Maya, Lam, Evan C., Feldman, Jared, Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2022

Structural and genetic basis for development of broadly neutralizing influenza antibodies

por Lingwood, Daniel, McTamney, Patrick M., Yassine, Hadi M., Whittle, James R. R., Guo, Xiaoti, Boyington, Jeffrey C., Wei, Chih-Jen, Nabel, Gary J.
Publicado 2012

Pre-existing Fc profiles shape the evolution of neutralizing antibody breadth following influenza vaccination

por Boudreau, Carolyn M., Burke, John S., Roederer, Alexander L., Gorman, Matthew J., Mundle, Sophia, Lingwood, Daniel, Delagrave, Simon, Sridhar, Saranya, Ross, Ted M., Kleanthous, Harry, Alter, Galit
Publicado 2023

Engineering an Antibody V Gene-Selective Vaccine

por Ronsard, Larance, Yousif, Ashraf S., Peabody, Julianne, Okonkwo, Vintus, Devant, Pascal, Mogus, Alemu Tekewe, Barnes, Ralston M., Rohrer, Daniel, Lonberg, Nils, Peabody, David, Chackerian, Bryce, Lingwood, Daniel
Publicado 2021

The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

por Yousif, Ashraf S., Ronsard, Larance, Shah, Pankaj, Omatsu, Tatsushi, Sangesland, Maya, Bracamonte Moreno, Thalia, Lam, Evan C., Vrbanac, Vladimir D., Balazs, Alejandro B., Reinecker, Hans-Christian, Lingwood, Daniel
Publicado 2021

Antibody-mediated NK cell activation as a correlate of immunity against influenza infection

por Boudreau, Carolyn M., Burke, John S., Yousif, Ashraf S., Sangesland, Maya, Jastrzebski, Sandra, Verschoor, Chris, Kuchel, George, Lingwood, Daniel, Kleanthous, Harry, De Bruijn, Iris, Landolfi, Victoria, Sridhar, Saranya, Alter, Galit
Publicado 2023

Heterologous sarbecovirus receptor binding domains as scaffolds for SARS-CoV-2 receptor binding motif presentation

por Hauser, Blake M., Sangesland, Maya, Lam, Evan C., Denis, Kerri J. St., Sheehan, Maegan L., Vu, Mya L., Cheng, Agnes H., Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2023

Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens

por Read, Benjamin J., Won, Lori, Kraft, John C., Sappington, Isaac, Aung, Aereas, Wu, Shengwei, Bals, Julia, Chen, Chengbo, Lee, Kelly K., Lingwood, Daniel, King, Neil P., Irvine, Darrell J.
Publicado 2022

Antigen identification and high-throughput interaction mapping by reprogramming viral entry

por Dobson, Connor S., Reich, Anna N., Gaglione, Stephanie, Smith, Blake E., Kim, Ellen J., Dong, Jiayi, Ronsard, Larance, Okonkwo, Vintus, Lingwood, Daniel, Dougan, Michael, Dougan, Stephanie K., Birnbaum, Michael E.
Publicado 2022

Engaging an HIV vaccine target through the acquisition of low B cell affinity

por Ronsard, Larance, Yousif, Ashraf S., Nait Mohamed, Faez Amokrane, Feldman, Jared, Okonkwo, Vintus, McCarthy, Caitlin, Schnabel, Julia, Caradonna, Timothy, Barnes, Ralston M., Rohrer, Daniel, Lonberg, Nils, Schmidt, Aaron, Lingwood, Daniel
Publicado 2023

Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

por Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Lam, Evan, Denis, Kerri St., Boucau, Julie, Barczak, Amy K, Balazs, Alejandro B., Schmidt, Aaron, Lingwood, Daniel, Bathe, Mark
Publicado 2023

A Single Human V(H)-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood

por Sangesland, Maya, Yousif, Ashraf S., Ronsard, Larance, Kazer, Samuel W., Zhu, Alex Lee, Gatter, G. James, Hayward, Matthew R., Barnes, Ralston M., Quirindongo-Crespo, Maricel, Rohrer, Daniel, Lonberg, Nils, Kwon, Douglas, Shalek, Alex K., Lingwood, Daniel
Publicado 2020

Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting

por Hauser, Blake M., Sangesland, Maya, St. Denis, Kerri J., Lam, Evan C., Case, James Brett, Windsor, Ian W., Feldman, Jared, Caradonna, Timothy M., Kannegieter, Ty, Diamond, Michael S., Balazs, Alejandro B., Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2022

Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses

por Feldman, Jared, Bals, Julia, Altomare, Clara G., St. Denis, Kerri, Lam, Evan C., Hauser, Blake M., Ronsard, Larance, Sangesland, Maya, Moreno, Thalia Bracamonte, Okonkwo, Vintus, Hartojo, Nathania, Balazs, Alejandro B., Bajic, Goran, Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2021

Naive human B cells engage the receptor binding domain of SARS-CoV-2, variants of concern, and related sarbecoviruses

por Feldman, Jared, Bals, Julia, Altomare, Clara G., St. Denis, Kerri, Lam, Evan C., Hauser, Blake M., Ronsard, Larance, Sangesland, Maya, Moreno, Thalia Bracamonte, Okonkwo, Vintus, Hartojo, Nathania, Balazs, Alejandro B., Bajic, Goran, Lingwood, Daniel, Schmidt, Aaron G.
Publicado 2021

Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation

por Villar, Rina F., Patel, Jinal, Weaver, Grant C., Kanekiyo, Masaru, Wheatley, Adam K., Yassine, Hadi M., Costello, Catherine E., Chandler, Kevin B., McTamney, Patrick. M., Nabel, Gary J., McDermott, Adrian B., Mascola, John R., Carr, Steven A., Lingwood, Daniel
Publicado 2016

Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design

por Hauser, Blake M., Feldman, Jared, Sangesland, Maya, Ronsard, Larance, St. Denis, Kerri J., Sheehan, Maegan L., Cao, Yi, Boucau, Julie, Windsor, Ian W., Cheng, Agnes H., Vu, Mya L., Cardoso, Marcella R., Kannegieter, Ty, Balazs, Alejandro B., Lingwood, Daniel, Garcia-Beltran, Wilfredo F., Schmidt, Aaron G.
Publicado 2022