Synthesis and Antiviral Activity of a Series of 2′-C-Methyl-4′-thionucleoside Monophosphate Prodrugs

por Dentmon, Zackery W., Kaiser, Thomas M., Liotta, Dennis C.
Publicado 2020

Calculated conformer energies for organic molecules with multiple polar functionalities are method dependent: Taxol (case study)

por Lakdawala, Ami, Wang, Minmin, Nevins, Neysa, Liotta, Dennis C, Rusinska-Roszak, Danuta, Lozynski, Marek, Snyder, James P
Publicado 2001

Preclinical and clinical development of the anti-HIV, anti-HBV oxathiolane nucleoside analog emtricitabine

por Painter, George R., Rimsky, Laurence T., Furman, Phillip A., Liotta, Dennis C., Schinazi, Raymond F., Quinn, Joseph B.
Publicado 2003

NMDA receptor channel gating control by the pre-M1 helix

por McDaniel, Miranda J., Ogden, Kevin K., Kell, Steven A., Burger, Pieter B., Liotta, Dennis C., Traynelis, Stephen F.
Publicado 2020

Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols

por Pruett, Sarah T., Bushnev, Anatoliy, Hagedorn, Kerri, Adiga, Madhura, Haynes, Christopher A., Sullards, M. Cameron, Liotta, Dennis C., Merrill, Alfred H.
Publicado 2008

Small molecule CXCR4 antagonists block the HIV-1 Nef/CXCR4 axis and selectively initiate the apoptotic program in breast cancer cells

por Huang, Ming-Bo, Giesler, Kyle E., Katzman, Brooke M., Prosser, Anthony R., Truax, Valarie, Liotta, Dennis C., Wilson, Lawrence J., Bond, Vincent C.
Publicado 2018

Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors

por Regan, Michael C., Zhu, Zongjian, Yuan, Hongjie, Myers, Scott J., Menaldino, Dave S., Tahirovic, Yesim A., Liotta, Dennis C., Traynelis, Stephen F., Furukawa, Hiro
Publicado 2019

Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators

por Zimmerman, Sommer S., Khatri, Alpa, Garnier-Amblard, Ethel C., Mullasseril, Praseeda, Kurtkaya, Natalie L., Gyoneva, Stefka, Hansen, Kasper B., Traynelis, Stephen F., Liotta, Dennis C.
Publicado 2014

Correction to “Design, Synthesis, and Structure–Activity Relationship of a Novel Series of GluN2C-Selective Potentiators”

por Zimmerman, Sommer S., Khatri, Alpa, Garnier-Amblard, Ethel C., Mullasseril, Praseeda, Kurtkaya, Natalie L., Gyoneva, Stefka, Hansen, Kasper B., Traynelis, Stephen F., Liotta, Dennis C.
Publicado 2015

Inhibition of breast cancer metastasis to the lungs with UBS109

por Shoji, Mamoru, Qian, Wei Ping, Nagaraju, Ganji Purnachandra, Brat, Daniel J., Pessolano, Danielle, Luzietti, Rick, Chennamadhavuni, Spandan, Yamaguchi, Masayoshi, Yang, Lily, Liotta, Dennis C.
Publicado 2018

A structurally derived model of subunit‐dependent NMDA receptor function

por Gibb, Alasdair J., Ogden, Kevin K., McDaniel, Miranda J., Vance, Katie M., Kell, Steven A., Butch, Chris, Burger, Pieter, Liotta, Dennis C., Traynelis, Stephen F.
Publicado 2018

An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups

por Perszyk, Riley, Katzman, Brooke M, Kusumoto, Hirofumi, Kell, Steven A, Epplin, Matthew P, Tahirovic, Yesim A, Moore, Rhonda L, Menaldino, David, Burger, Pieter, Liotta, Dennis C, Traynelis, Stephen F
Publicado 2018

Novel GluN2B-Selective NMDA Receptor Negative Allosteric Modulator Possesses Intrinsic Analgesic Properties and Enhances Analgesia of Morphine in a Rodent Tail Flick Pain Model

por Harris, Lynnea D., Regan, Michael C., Myers, Scott J., Nocilla, Kelsey A., Akins, Nicholas S., Tahirovic, Yesim A., Wilson, Lawrence J., Dingledine, Ray, Furukawa, Hiro, Traynelis, Stephen F., Liotta, Dennis C.
Publicado 2023

Asymmetric synthesis of host-directed inhibitors of myxoviruses

por Moore, Terry W, Sana, Kasinath, Yan, Dan, Thepchatri, Pahk, Ndungu, John M, Saindane, Manohar T, Lockwood, Mark A, Natchus, Michael G, Liotta, Dennis C, Plemper, Richard K, Snyder, James P, Sun, Aiming
Publicado 2013

Tumor Angiogenesis Therapy Using Targeted Delivery of Paclitaxel to the Vasculature of Breast Cancer Metastases

por Zhu, Shijun, Kisiel, Walter, Lu, Yang J., Petersen, Lars C., Ndungu, John M., Moore, Terry W., Parker, Ernest T., Sun, Aiming, Liotta, Dennis C., El-Rayes, Bassel F., Brat, Daniel J., Snyder, James P., Shoji, Mamoru
Publicado 2014

Expanding the toolbox of metabolically stable lipid prodrug strategies

por Toti, Kiran S., Pribut, Nicole, D’Erasmo, Michael, Dasari, Madhuri, Sharma, Savita K., Bartsch, Perry W., Burton, Samantha L., Gold, Hannah B., Bushnev, Anatoliy, Derdeyn, Cynthia A., Basson, Adriaan E., Liotta, Dennis C., Miller, Eric J.
Publicado 2023

Biased modulators of NMDA receptors control channel opening and ion selectivity

por Perszyk, Riley E., Swanger, Sharon A., Shelley, Chris, Khatri, Alpa, Fernandez-Cuervo, Gabriela, Epplin, Matthew P., Zhang, Jing, Le, Phuong, Bülow, Pernille, Garnier-Amblard, Ethel, Gangireddy, Pavan Kumar Reddy, Bassell, Gary J., Yuan, Hongjie, Menaldino, David S., Liotta, Dennis C., Liebeskind, Lanny S., Traynelis, Stephen F.
Publicado 2020

Development of a Unique Small Molecule Modulator of CXCR4

por Liang, Zhongxing, Zhan, Weiqiang, Zhu, Aizhi, Yoon, Younghyoun, Lin, Songbai, Sasaki, Maiko, Klapproth, Jan-Michael A., Yang, Hua, Grossniklaus, Hans E., Xu, Jianguo, Rojas, Mauricio, Voll, Ronald J., Goodman, Mark M., Arrendale, Richard F., Liu, Jin, Yun, C. Chris, Snyder, James P., Liotta, Dennis C., Shim, Hyunsuk
Publicado 2012

Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 M(pro) Inhibitors

por Jacobs, Leon, van der Westhuyzen, Aletta, Pribut, Nicole, Dentmon, Zackery W., Cui, Dan, D’Erasmo, Michael P., Bartsch, Perry W., Liu, Ken, Cox, Robert M., Greenlund, Sujay F., Plemper, Richard K., Mitchell, Deborah, Marlow, Joshua, Andrews, Meghan K., Krueger, Rebecca E., Sticher, Zachary M., Kolykhalov, Alexander A., Natchus, Michael G., Zhou, Bin, Pelly, Stephen C., Liotta, Dennis C.
Publicado 2023

Development of a Dihydroquinoline–Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor

por D’Erasmo, Michael P., Akins, Nicholas S., Ma, Peipei, Jing, Yao, Swanger, Sharon A., Sharma, Savita K., Bartsch, Perry W., Menaldino, David S., Arcoria, Paul J., Bui, Thi-Thien, Pons-Bennaceur, Alexandre, Le, Phuong, Allen, James P., Ullman, Elijah Z., Nocilla, Kelsey A., Zhang, Jing, Perszyk, Riley E., Kim, Sukhan, Acker, Timothy M., Taz, Azmain, Burton, Samantha L., Coe, Kevin, Fritzemeier, Russell G., Burnashev, Nail, Yuan, Hongjie, Liotta, Dennis C., Traynelis, Stephen F.
Publicado 2023