Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends

por Nepali, Kunal, Liou, Jing-Ping
Publicado 2021

Recent Update of HDAC Inhibitors in Lymphoma

por Chen, I-Chung, Sethy, Bidyadhar, Liou, Jing-Ping
Publicado 2020

Beyond the vaccines: a glance at the small molecule and peptide-based anti-COVID19 arsenal

por Nepali, Kunal, Sharma, Ram, Sharma, Sachin, Thakur, Amandeep, Liou, Jing-Ping
Publicado 2022

Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

por Tsai, I-Ting, Kuo, Ching-Chuan, Liou, Jing-Ping, Chang, Jang-Yang
Publicado 2018

The novel histone de acetylase 6 inhibitor, MPT0G211, ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model

por Fan, Sheng-Jun, Huang, Fang-I, Liou, Jing-Ping, Yang, Chia-Ron
Publicado 2018

Molecular mechanisms underlying the antitumor activity of (E)-N-hydroxy-3-(1-(4-methoxyphenylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)acrylamide in human colorectal cancer cells i...

por Chen, Chun-Han, Lee, Chia-Hwa, Liou, Jing-Ping, Teng, Che-Ming, Pan, Shiow-Lin
Publicado 2015

Identification of 7-(4′-Cyanophenyl)indoline-1-benzenesulfonamide as a mitotic inhibitor to induce apoptotic cell death and inhibit autophagy in human colorectal cancer cells

por Wu, Tung-Yun, Cho, Ting-Yu, Lu, Chung-Kuang, Liou, Jing-Ping, Chen, Mei-Chuan
Publicado 2017

MPT0G612, a Novel HDAC6 Inhibitor, Induces Apoptosis and Suppresses IFN-γ-Induced Programmed Death-Ligand 1 in Human Colorectal Carcinoma Cells

por Chen, Mei-Chuan, Lin, Yu-Chen, Liao, Yu-Hsuan, Liou, Jing-Ping, Chen, Chun-Han
Publicado 2019

CK1δ as a potential therapeutic target to treat bladder cancer

por Lin, Yu-Chen, Chen, Mei-Chuan, Hsieh, Tsung-Han, Liou, Jing-Ping, Chen, Chun-Han
Publicado 2020

Glioblastoma: Current Status, Emerging Targets, and Recent Advances

por Thakur, Amandeep, Faujdar, Chetna, Sharma, Ram, Sharma, Sachin, Malik, Basant, Nepali, Kunal, Liou, Jing Ping
Publicado 2022

Intermediary Metabolite Precursor Dimethyl-2-Ketoglutarate Stabilizes Hypoxia-Inducible Factor-1α by Inhibiting Prolyl-4-Hydroxylase PHD2

por Hou, Peifeng, Kuo, Ching-Ying, Cheng, Chun-Ting, Liou, Jing-Ping, Ann, David K., Chen, Qiang
Publicado 2014

MT-4 Suppresses Resistant Ovarian Cancer Growth through Targeting Tubulin and HSP27

por Pai, Hui Chen, Kumar, Sunil, Shen, Chien-Chang, Liou, Jing Ping, Pan, Shiow Lin, Teng, Che Ming
Publicado 2015

Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis

por Huang, Yen-Chia, Huang, Fang-I, Mehndiratta, Samir, Lai, Ssu-Chia, Liou, Jing-Ping, Yang, Chia-Ron
Publicado 2015

Trichlorobenzene-substituted azaaryl compounds as novel FGFR inhibitors exhibiting potent antitumor activity in bladder cancer cells in vitro and in vivo

por Chen, Chun-Han, Liu, Yi-Min, Pan, Shiow-Lin, Liu, Yun-Ru, Liou, Jing-Ping, Yen, Yun
Publicado 2016

Targeting Autophagy by MPT0L145, a Highly Potent PIK3C3 Inhibitor, Provides Synergistic Interaction to Targeted or Chemotherapeutic Agents in Cancer Cells

por Chen, Chun-Han, Hsieh, Tsung-Han, Lin, Yu-Chen, Liu, Yun-Ru, Liou, Jing-Ping, Yen, Yun
Publicado 2019

Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells

por Tsai, Feng-Lung, Huang, Han-Li, Lai, Mei-Jung, Liou, Jing-Ping, Pan, Shiow-Lin, Yang, Chia-Ron
Publicado 2023

A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and E-cadherin

por Wang, Li-Ting, Liou, Jing-Ping, Li, Yu-Hsuan, Liu, Yi-Min, Pan, Shiow-Lin, Teng, Che-Ming
Publicado 2014

Optimization and Development of Selective Histone Deacetylase Inhibitor (MPT0B291)-Loaded Albumin Nanoparticles for Anticancer Therapy

por Putri, Athika Darumas, Chen, Pai-Shan, Su, Yu-Lin, Lin, Jia-Pei, Liou, Jing-Ping, Hsieh, Chien-Ming
Publicado 2021

Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

por Mehndiratta, Samir, Chen, Mei-Chuan, Chao, Yuh-Hsuan, Lee, Cheng-Hsin, Liou, Jing-Ping, Lai, Mei-Jung, Lee, Hsueh-Yun
Publicado 2020

A Novel Synthetic Microtubule Inhibitor, MPT0B214 Exhibits Antitumor Activity in Human Tumor Cells through Mitochondria-Dependent Intrinsic Pathway

por Chiang, Nai-Jung, Lin, Ching-I, Liou, Jing-Ping, Kuo, Ching-Chuan, Chang, Chi-Yen, Chen, Li-Tzong, Chang, Jang-Yang
Publicado 2013