Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells

por Grigoryan, Ani, Pospiech, Johannes, Krämer, Stephen, Lipka, Daniel, Liehr, Thomas, Geiger, Hartmut, Kimura, Hiroshi, Mulaw, Medhanie A., Florian, Maria Carolina
Publicado 2021

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium

por Schlereth, Katharina, Weichenhan, Dieter, Bauer, Tobias, Heumann, Tina, Giannakouri, Evangelia, Lipka, Daniel, Jaeger, Samira, Schlesner, Matthias, Aloy, Patrick, Eils, Roland, Plass, Christoph, Augustin, Hellmut G
Publicado 2018

Intracellular Retention of ABL Kinase Inhibitors Determines Commitment to Apoptosis in CML Cells

por Lipka, Daniel B., Wagner, Marie-Christine, Dziadosz, Marek, Schnöder, Tina, Heidel, Florian, Schemionek, Mirle, Melo, Junia V., Kindler, Thomas, Müller-Tidow, Carsten, Koschmieder, Steffen, Fischer, Thomas
Publicado 2012

CREBBP is a target of epigenetic, but not genetic, modification in juvenile myelomonocytic leukemia

por Fluhr, Silvia, Boerries, Melanie, Busch, Hauke, Symeonidi, Aikaterini, Witte, Tania, Lipka, Daniel B, Mücke, Oliver, Nöllke, Peter, Krombholz, Christopher Felix, Niemeyer, Charlotte M, Plass, Christoph, Flotho, Christian
Publicado 2016

Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha

por Schubert, Claudia, Allhoff, Manuel, Tillmann, Stefan, Maié, Tiago, Costa, Ivan G., Lipka, Daniel B., Schemionek, Mirle, Feldberg, Kristina, Baumeister, Julian, Brümmendorf, Tim H., Chatain, Nicolas, Koschmieder, Steffen
Publicado 2019

Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction

por Niemöller, Christoph, Wehrle, Julius, Riba, Julian, Claus, Rainer, Renz, Nathalie, Rhein, Janika, Bleul, Sabine, Stosch, Juliane M., Duyster, Justus, Plass, Christoph, Lutsik, Pavlo, Lipka, Daniel B., Lübbert, Michael, Becker, Heiko
Publicado 2021

Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia

por Stieglitz, Elliot, Mazor, Tali, Olshen, Adam B., Geng, Huimin, Gelston, Laura C., Akutagawa, Jon, Lipka, Daniel B., Plass, Christoph, Flotho, Christian, Chehab, Farid F., Braun, Benjamin S., Costello, Joseph F., Loh, Mignon L.
Publicado 2017

S122: MUTANT IDH1 HIJACKS DIFFERENTIATION PROGRAMS IN MYELOID PROGENITOR CELLS TO IMPAIR GRANULOCYTIC DIFFERENTIATION.

por Hakobyan, Mariam, Langstein, Jens, Kleinert, Emely, Schönung, Maximilian, Hartmann, Mark, Rohdjess, Hannah, Staeble, Sina, Claus, Rainer, Bullinger, Lars, Oakes, Christopher, Rippe, Karsten, Fröhling, Stefan, Pusch, Stefan, Plass, Christoph, Milsom, Michael, Lipka, Daniel B.
Publicado 2023

Dysregulated serum response factor triggers formation of hepatocellular carcinoma

por Ohrnberger, Stefan, Thavamani, Abhishek, Braeuning, Albert, Lipka, Daniel B, Kirilov, Milen, Geffers, Robert, Authenrieth, Stella E, Römer, Michael, Zell, Andreas, Bonin, Michael, Schwarz, Michael, Schütz, Günther, Schirmacher, Peter, Plass, Christoph, Longerich, Thomas, Nordheim, Alfred
Publicado 2015

A Phase Ib Dose-finding Study of Panobinostat and Ruxolitinib in Myelofibrosis

por Harrison, Claire, Heidel, Florian H., Vannucchi, Alessandro M., Kiladjian, Jean-Jacques, Hayat, Amjad, Passamonti, Francesco, Conneally, Eibhlin, Kindler, Thomas, Martino, Bruno, Lipka, Daniel B., Stefanelli, Tommaso, Roussou, Pantelia, Germano, Davide, Ewan, Jacqueline, Ribrag, Vincent
Publicado 2022

LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells

por Grigoryan, Ani, Guidi, Novella, Senger, Katharina, Liehr, Thomas, Soller, Karin, Marka, Gina, Vollmer, Angelika, Markaki, Yolanda, Leonhardt, Heinrich, Buske, Christian, Lipka, Daniel B., Plass, Christoph, Zheng, Yi, Mulaw, Medhanie A., Geiger, Hartmut, Florian, Maria Carolina
Publicado 2018

The antileukemic activity of decitabine upon PML/RARA-negative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation

por Meier, Ruth, Greve, Gabriele, Zimmer, Dennis, Bresser, Helena, Berberich, Bettina, Langova, Ralitsa, Stomper, Julia, Rubarth, Anne, Feuerbach, Lars, Lipka, Daniel B., Hey, Joschka, Grüning, Björn, Brors, Benedikt, Duyster, Justus, Plass, Christoph, Becker, Heiko, Lübbert, Michael
Publicado 2022

Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma

por Goeppert, Benjamin, Toth, Reka, Singer, Stephan, Albrecht, Thomas, Lipka, Daniel B., Lutsik, Pavlo, Brocks, David, Baehr, Marion, Muecke, Oliver, Assenov, Yassen, Gu, Lei, Endris, Volker, Stenzinger, Albrecht, Mehrabi, Arianeb, Schirmacher, Peter, Plass, Christoph, Weichenhan, Dieter, Roessler, Stephanie
Publicado 2019

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells

por Merkle, Ruth, Steiert, Bernhard, Salopiata, Florian, Depner, Sofia, Raue, Andreas, Iwamoto, Nao, Schelker, Max, Hass, Helge, Wäsch, Marvin, Böhm, Martin E., Mücke, Oliver, Lipka, Daniel B., Plass, Christoph, Lehmann, Wolf D., Kreutz, Clemens, Timmer, Jens, Schilling, Marcel, Klingmüller, Ursula
Publicado 2016

Translocation t(6;7) in AML-M4 cell line GDM-1 results in MNX1 activation through enhancer-hijacking

por Weichenhan, Dieter, Riedel, Anna, Meinen, Charlotte, Basic, Alisa, Toth, Reka, Bähr, Marion, Lutsik, Pavlo, Hey, Joschka, Sollier, Etienne, Toprak, Umut H., Kelekçi, Simge, Lin, Yu-Yu, Hakobyan, Mariam, Touzart, Aurore, Goyal, Ashish, Wierzbinska, Justyna A., Schlesner, Matthias, Westermann, Frank, Lipka, Daniel B., Plass, Christoph
Publicado 2023

Epigenetic stress responses induce muscle stem cell aging by Hoxa9 developmental signals

por Schwoerer, Simon, Becker, Friedrich, Feller, Christian, Baig, Ali H., Koeber, Ute, Henze, Henriette, Kraus, Johann M., Xin, Beibei, Lechel, André, Lipka, Daniel B., Varghese, Christy S., Schmidt, Manuel, Rohs, Remo, Aebersold, Ruedi, Medina, Kay L., Kestler, Hans A., Neri, Francesco, von Maltzahn, Julia, Tuempel, Stefan, Rudolph, K. Lenhard
Publicado 2016

Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL

por Wierzbinska, Justyna A., Toth, Reka, Ishaque, Naveed, Rippe, Karsten, Mallm, Jan-Philipp, Klett, Lara C., Mertens, Daniel, Zenz, Thorsten, Hielscher, Thomas, Seifert, Marc, Küppers, Ralf, Assenov, Yassen, Lutsik, Pavlo, Stilgenbauer, Stephan, Roessner, Philipp M., Seiffert, Martina, Byrd, John, Oakes, Christopher C., Plass, Christoph, Lipka, Daniel B.
Publicado 2020

Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia

por Sonnet, Miriam, Claus, Rainer, Becker, Natalia, Zucknick, Manuela, Petersen, Jana, Lipka, Daniel B, Oakes, Christopher C, Andrulis, Mindaugas, Lier, Amelie, Milsom, Michael D, Witte, Tania, Gu, Lei, Kim-Wanner, Soo-Zin, Schirmacher, Peter, Wulfert, Michael, Gattermann, Norbert, Lübbert, Michael, Rosenbauer, Frank, Rehli, Michael, Bullinger, Lars, Weichenhan, Dieter, Plass, Christoph
Publicado 2014

Effects of Label Noise on Deep Learning-Based Skin Cancer Classification

por Hekler, Achim, Kather, Jakob N., Krieghoff-Henning, Eva, Utikal, Jochen S., Meier, Friedegund, Gellrich, Frank F., Upmeier zu Belzen, Julius, French, Lars, Schlager, Justin G., Ghoreschi, Kamran, Wilhelm, Tabea, Kutzner, Heinz, Berking, Carola, Heppt, Markus V., Haferkamp, Sebastian, Sondermann, Wiebke, Schadendorf, Dirk, Schilling, Bastian, Izar, Benjamin, Maron, Roman, Schmitt, Max, Fröhling, Stefan, Lipka, Daniel B., Brinker, Titus J.
Publicado 2020

Integrating Patient Data Into Skin Cancer Classification Using Convolutional Neural Networks: Systematic Review

por Höhn, Julia, Hekler, Achim, Krieghoff-Henning, Eva, Kather, Jakob Nikolas, Utikal, Jochen Sven, Meier, Friedegund, Gellrich, Frank Friedrich, Hauschild, Axel, French, Lars, Schlager, Justin Gabriel, Ghoreschi, Kamran, Wilhelm, Tabea, Kutzner, Heinz, Heppt, Markus, Haferkamp, Sebastian, Sondermann, Wiebke, Schadendorf, Dirk, Schilling, Bastian, Maron, Roman C, Schmitt, Max, Jutzi, Tanja, Fröhling, Stefan, Lipka, Daniel B, Brinker, Titus Josef
Publicado 2021