TIC10/ONC201: a bend in the road to clinical development

por Greer, Yoshimi Endo, Lipkowitz, Stanley
Publicado 2015

Novel Apoptosis-Inducing Agents for the Treatment of Cancer, a New Arsenal in the Toolbox

por Lim, Bora, Greer, Yoshimi, Lipkowitz, Stanley, Takebe, Naoko
Publicado 2019

Enigma Prevents Cbl-c-Mediated Ubiquitination and Degradation of RETMEN2A

por Kales, Stephen C., Nau, Marion M., Merchant, Anand S., Lipkowitz, Stanley
Publicado 2014

Targeting TRAIL Death Receptors in Triple-Negative Breast Cancers: Challenges and Strategies for Cancer Therapy

por Kundu, Manjari, Greer, Yoshimi Endo, Dine, Jennifer L., Lipkowitz, Stanley
Publicado 2022

Cbl-c Ubiquitin Ligase Activity Is Increased via the Interaction of Its RING Finger Domain with a LIM Domain of the Paxillin Homolog, Hic 5

por Ryan, Philip E., Kales, Stephen C., Yadavalli, Rajgopal, Nau, Marion M., Zhang, Han, Lipkowitz, Stanley
Publicado 2012

Targeting Mitochondria with ClpP Agonists as a Novel Therapeutic Opportunity in Breast Cancer

por Wedam, Rohan, Greer, Yoshimi Endo, Wisniewski, David J., Weltz, Sarah, Kundu, Manjari, Voeller, Donna, Lipkowitz, Stanley
Publicado 2023

Cbl interacts with multiple E2s in vitro and in cells

por Liyasova, Mariya S., Ma, Ke, Voeller, Donna, Ryan, Philip E., Chen, Jinqiu, Klevit, Rachel E., Lipkowitz, Stanley
Publicado 2019

Recruitment of Cbl-b to B Cell Antigen Receptor Couples Antigen Recognition to Toll-Like Receptor 9 Activation in Late Endosomes

por Veselits, Margaret, Tanaka, Azusa, Lipkowitz, Stanley, O'Neill, Shannon, Sciammas, Roger, Finnegan, Alison, Zhang, Jian, Clark, Marcus R.
Publicado 2014

Loss of function Cbl-c mutations in solid tumors

por Daniels, Silvano Rakeem, Liyasova, Mariya, Kales, Stephen C., Nau, Marion M., Ryan, Philip E., Green, Jeffrey E., Lipkowitz, Stanley
Publicado 2019

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgro...

por Greer, Yoshimi Endo, Gilbert, Samuel F., Gril, Brunilde, Narwal, Rajesh, Peacock Brooks, Danielle L., Tice, David A., Steeg, Patricia S., Lipkowitz, Stanley
Publicado 2019

Suberitamides A–C, Aryl Alkaloids from a Pseudosuberites sp. Marine Sponge that Inhibit Cbl-b Ubiquitin Ligase Activity

por Kim, Chang-Kwon, Wang, Dongdong, Wilson, Brice A. P., Saurí, Josep, Voeller, Donna, Lipkowitz, Stanley, O’Keefe, Barry R., Gustafson, Kirk R.
Publicado 2020

Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening

por Garimella, Sireesha V, Gehlhaus, Kristie, Dine, Jennifer L, Pitt, Jason J, Grandin, Magdalena, Chakka, Sirisha, Nau, Marion M, Caplen, Natasha J, Lipkowitz, Stanley
Publicado 2014

E3 Ubiquitin Ligase Cbl-b Suppresses Proallergic T Cell Development and Allergic Airway Inflammation

por Qiao, Guilin, Ying, Haiyan, Zhao, Yixia, Liang, Yanran, Guo, Hui, Shen, Huifeng, Li, Zhenping, Solway, Julian, Tao, Enxiang, Chiang, Y. Jeffrey, Lipkowitz, Stanley, Penninger, Josef M., Langdon, Wallace Y., Zhang, Jian
Publicado 2014

Agelasine Diterpenoids and Cbl-b Inhibitory Ageliferins from the Coralline Demosponge Astrosclera willeyana

por Jiang, Wei, Wang, Dongdong, Wilson, Brice A. P., Kang, Unwoo, Bokesch, Heidi R., Smith, Emily A., Wamiru, Antony, Goncharova, Ekaterina I., Voeller, Donna, Lipkowitz, Stanley, O’Keefe, Barry R., Gustafson, Kirk R.
Publicado 2021

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

por Wisniewski, David J., Liyasova, Mariya S., Korrapati, Soumya, Zhang, Xu, Ratnayake, Shashikala, Chen, Qingrong, Gilbert, Samuel F., Catalano, Alexis, Voeller, Donna, Meerzaman, Daoud, Guha, Udayan, Porat-Shliom, Natalie, Annunziata, Christina M., Lipkowitz, Stanley
Publicado 2022

Improving the Odds in Advanced Breast Cancer With Combination Immunotherapy: Stepwise Addition of Vaccine, Immune Checkpoint Inhibitor, Chemotherapy, and HDAC Inhibitor in Advanced...

por Gatti-Mays, Margaret E., Gameiro, Sofia R., Ozawa, Yohei, Knudson, Karin M., Hicks, Kristin C., Palena, Claudia, Cordes, Lisa M., Steinberg, Seth M., Francis, Deneise, Karzai, Fatima, Lipkowitz, Stanley, Donahue, Renee N., Jochems, Caroline, Schlom, Jeffrey, Gulley, James L.
Publicado 2021

A phase I study of the PD-L1 inhibitor, durvalumab, in combination with a PARP inhibitor, olaparib, and a VEGFR1–3 inhibitor, cediranib, in recurrent women’s cancers with biomarker...

por Zimmer, Alexandra S., Nichols, Erin, Cimino-Mathews, Ashley, Peer, Cody, Cao, Liang, Lee, Min-Jung, Kohn, Elise C., Annunziata, Christina M., Lipkowitz, Stanley, Trepel, Jane B., Sharma, Rajni, Mikkilineni, Lekha, Gatti-Mays, Margaret, Figg, William D., Houston, Nicole D., Lee, Jung-Min
Publicado 2019

Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer

por Fennell, Emily M. J., Aponte-Collazo, Lucas J., Pathmasiri, Wimal, Rushing, Blake R., Barker, Natalie K., Partridge, Megan C., Li, Yuan-Yuan, White, Cody A., Greer, Yoshimi E., Herring, Laura E., Lipkowitz, Stanley, Sumner, Susan C. J., Iwanowicz, Edwin J., Graves, Lee M.
Publicado 2023

CBL Is Frequently Altered in Lung Cancers: Its Relationship to Mutations in MET and EGFR Tyrosine Kinases

por Tan, Yi-Hung Carol, Krishnaswamy, Soundararajan, Nandi, Suvobroto, Kanteti, Rajani, Vora, Sapana, Onel, Kenan, Hasina, Rifat, Lo, Fang-Yi, El-Hashani, Essam, Cervantes, Gustavo, Robinson, Matthew, Kales, Stephen C., Lipkowitz, Stanley, Karrison, Theodore, Sattler, Martin, Vokes, Everett E., Wang, Yi-Ching, Salgia, Ravi
Publicado 2010

Phase I/Ib study of olaparib and carboplatin in women with triple negative breast cancer

por Lee, Jung-Min, Hays, John L., Chiou, Victoria L., Annunziata, Christina M., Swisher, Elizabeth M., Harrell, Maria I., Yu, Minshu, Gordon, Nicolas, Sissung, Tristan M., Ji, Jiuping, Figg, William D., Minasian, Lori, Lipkowitz, Stanley, Wood, Bradford J., Doroshow, James, Kohn, Elise C.
Publicado 2017