Dose–Exposure–Response Analysis of the Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone on UACR and eGFR: An Analysis from FIDELIO-DKD

por Goulooze, Sebastiaan Camiel, Heerspink, Hiddo J. L., van Noort, Martijn, Snelder, Nelleke, Brinker, Meike, Lippert, Joerg, Eissing, Thomas
Publicado 2022

Evaluation of the Efficacy and Safety of Rivaroxaban Using a Computer Model for Blood Coagulation

por Burghaus, Rolf, Coboeken, Katrin, Gaub, Thomas, Kuepfer, Lars, Sensse, Anke, Siegmund, Hans-Ulrich, Weiss, Wolfgang, Mueck, Wolfgang, Lippert, Joerg
Publicado 2011

Finerenone Dose–Exposure–Serum Potassium Response Analysis of FIDELIO-DKD Phase III: The Role of Dosing, Titration, and Inclusion Criteria

por Goulooze, Sebastiaan Camiel, Snelder, Nelleke, Seelmann, Andreas, Horvat-Broecker, Andrea, Brinker, Meike, Joseph, Amer, Garmann, Dirk, Lippert, Joerg, Eissing, Thomas
Publicado 2021

Finerenone Dose-Exposure-Response for the Primary Kidney Outcome in FIDELIO-DKD Phase III: Population Pharmacokinetic and Time-to-Event Analysis

por van den Berg, Paul, Ruppert, Martijn, Mesic, Emir, Snelder, Nelleke, Seelmann, Andreas, Heinig, Roland, Joseph, Amer, Garmann, Dirk, Lippert, Joerg, Eissing, Thomas
Publicado 2021

Development of a Physiologically Based Computational Kidney Model to Describe the Renal Excretion of Hydrophilic Agents in Rats

por Niederalt, Christoph, Wendl, Thomas, Kuepfer, Lars, Claassen, Karina, Loosen, Roland, Willmann, Stefan, Lippert, Joerg, Schultze-Mosgau, Marcus, Winkler, Julia, Burghaus, Rolf, Bräutigam, Matthias, Pietsch, Hubertus, Lengsfeld, Philipp
Publicado 2013

Baseline clusters and the response to positive airway pressure treatment in obstructive sleep apnoea patients: longitudinal data from the European Sleep Apnea Database cohort

por Yassen, Ashraf, Coboeken, Katrin, Bailly, Sébastien, Burghaus, Rolf, Buskova, Jitka, Dogas, Zoran, Drummond, Marta, Gouveris, Haralampos, Joppa, Pavol, Lippert, Joerg, Lombardi, Carolina, Mihaicuta, Stefan, Pépin, Jean Louis, Zou, Ding, Hedner, Jan, Grote, Ludger
Publicado 2022

Translational learning from clinical studies predicts drug pharmacokinetics across patient populations

por Krauss, Markus, Hofmann, Ute, Schafmayer, Clemens, Igel, Svitlana, Schlender, Jan, Mueller, Christian, Brosch, Mario, von Schoenfels, Witigo, Erhart, Wiebke, Schuppert, Andreas, Block, Michael, Schaeffeler, Elke, Boehmer, Gabriele, Goerlitz, Linus, Hoecker, Jan, Lippert, Joerg, Kerb, Reinhold, Hampe, Jochen, Kuepfer, Lars, Schwab, Matthias
Publicado 2017

A Computational Systems Biology Software Platform for Multiscale Modeling and Simulation: Integrating Whole-Body Physiology, Disease Biology, and Molecular Reaction Networks

por Eissing, Thomas, Kuepfer, Lars, Becker, Corina, Block, Michael, Coboeken, Katrin, Gaub, Thomas, Goerlitz, Linus, Jaeger, Juergen, Loosen, Roland, Ludewig, Bernd, Meyer, Michaela, Niederalt, Christoph, Sevestre, Michael, Siegmund, Hans-Ulrich, Solodenko, Juri, Thelen, Kirstin, Telle, Ulrich, Weiss, Wolfgang, Wendl, Thomas, Willmann, Stefan, Lippert, Joerg
Publicado 2011

Immunogenicity of COVID-19 Tozinameran Vaccination in Patients on Chronic Dialysis

por Schrezenmeier, Eva, Bergfeld, Leon, Hillus, David, Lippert, Joerg-Detlev, Weber, Ulrike, Tober-Lau, Pinkus, Landgraf, Irmgard, Schwarz, Tatjana, Kappert, Kai, Stefanski, Ana-Luisa, Sattler, Arne, Kotsch, Katja, Dörner, Thomas, Sander, Leif Erik, Budde, Klemens, Halleck, Fabian, Kurth, Florian, Corman, Victor Max, Choi, Mira
Publicado 2021

Algorithmic surveillance of ICU patients with acute respiratory distress syndrome (ASIC): protocol for a multicentre stepped-wedge cluster randomised quality improvement strategy

por Marx, Gernot, Bickenbach, Johannes, Fritsch, Sebastian Johannes, Kunze, Julian Benedict, Maassen, Oliver, Deffge, Saskia, Kistermann, Jennifer, Haferkamp, Silke, Lutz, Irina, Voellm, Nora Kristiana, Lowitsch, Volker, Polzin, Richard, Sharafutdinov, Konstantin, Mayer, Hannah, Kuepfer, Lars, Burghaus, Rolf, Schmitt, Walter, Lippert, Joerg, Riedel, Morris, Barakat, Chadi, Stollenwerk, André, Fonck, Simon, Putensen, Christian, Zenker, Sven, Erdfelder, Felix, Grigutsch, Daniel, Kram, Rainer, Beyer, Susanne, Kampe, Knut, Gewehr, Jan Erik, Salman, Friederike, Juers, Patrick, Kluge, Stefan, Tiller, Daniel, Wisotzki, Emilia, Gross, Sebastian, Homeister, Lorenz, Bloos, Frank, Scherag, André, Ammon, Danny, Mueller, Susanne, Palm, Julia, Simon, Philipp, Jahn, Nora, Loeffler, Markus, Wendt, Thomas, Schuerholz, Tobias, Groeber, Petra, Schuppert, Andreas
Publicado 2021