Cell-specific exon methylation and CTCF binding in neurons regulate calcium ion channel splicing and function

por López Soto, Eduardo Javier, Lipscombe, Diane
Publicado 2020

Epigenetic control of ion channel expression and cell-specific splicing in nociceptors: Chronic pain mechanisms and potential therapeutic targets

por Lipscombe, Diane, Lopez-Soto, E. Javier
Publicado 2021

Spinal morphine but not ziconotide or gabapentin analgesia is affected by alternative splicing of voltage-gated calcium channel Ca(V)2.2 pre-mRNA

por Jiang, Yu-Qiu, Andrade, Arturo, Lipscombe, Diane
Publicado 2013

Tracks through the genome to physiological events

por Lipscombe, Diane, Pan, Jen Q., Schorge, Stephanie
Publicado 2015

Opioid inhibition of N-type Ca(2+) channels and spinal analgesia couple to alternative splicing

por Andrade, Arturo, Denome, Sylvia, Jiang, Yu-Qiu, Marangoudakis, Spiro, Lipscombe, Diane
Publicado 2010

ω-Phonetoxins inhibit voltage-gated calcium Ca(V)2.2 ion channel splice isoforms of dorsal root ganglia

por Castro-Junior, Célio, Gomez, Marcus Vinícius, Borges, Marcia Helena, Lipscombe, Diane, Andrade, Arturo
Publicado 2023

Cell-Specific RNA Binding Protein Rbfox2 Regulates Ca(V)2.2 mRNA Exon Composition and Ca(V)2.2 Current Size

por Allen, Summer E., Toro, Cecilia P., Andrade, Arturo, López-Soto, Eduardo J., Denome, Sylvia, Lipscombe, Diane
Publicado 2017

Cacna1b alternative splicing impacts excitatory neurotransmission and is linked to behavioral responses to aversive stimuli

por Bunda, Alexandra, LaCarubba, Brianna, Bertolino, Melanie, Akiki, Marie, Bath, Kevin, Lopez-Soto, Javier, Lipscombe, Diane, Andrade, Arturo
Publicado 2019

Bioluminescent optogenetic (BL-OG) activation of neurons during mouse postnatal brain development

por Crespo, Emmanuel L., Prakash, Mansi, Bjorefeldt, Andreas, Medendorp, William E., Shaner, Nathan C., Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute
Publicado 2021

Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated Ca(V)2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin

por DuBreuil, Daniel M., Lopez Soto, Eduardo Javier, Daste, Simon, Meir, Remy, Li, Daniel, Wainger, Brian, Fleischmann, Alexander, Lipscombe, Diane
Publicado 2021

A Bioluminescent Activity Dependent (BLADe) Platform for Converting Neuronal Activity to Photoreceptor Activation

por Crespo, Emmanuel L., Pal, Akash, Prakash, Mansi, Silvagnoli, Alexander D., Zaidi, Zohair, Gomez-Ramirez, Manuel, Tree, Maya O., Shaner, Nathan C., Lipscombe, Diane, Moore, Christopher, Hochgeschwender, Ute
Publicado 2023

Decreased microRNA levels lead to deleterious increases in neuronal M2 muscarinic receptors in Spinal Muscular Atrophy models

por O'Hern, Patrick J, do Carmo G. Gonçalves, Inês, Brecht, Johanna, López Soto, Eduardo Javier, Simon, Jonah, Chapkis, Natalie, Lipscombe, Diane, Kye, Min Jeong, Hart, Anne C
Publicado 2017

Selective control of synaptically-connected circuit elements by all-optical synapses

por Prakash, Mansi, Murphy, Jeremy, St Laurent, Robyn, Friedman, Nina, Crespo, Emmanuel L., Bjorefeldt, Andreas, Pal, Akash, Bhagat, Yuvraj, Kauer, Julie A., Shaner, Nathan C., Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute
Publicado 2022

Analysing an allelic series of rare missense variants of CACNA1I in a Swedish schizophrenia cohort

por Baez-Nieto, David, Allen, Andrew, Akers-Campbell, Seth, Yang, Lingling, Budnik, Nikita, Pupo, Amaury, Shin, Young-Cheul, Genovese, Giulio, Liao, Maofu, Pérez-Palma, Eduardo, Heyne, Henrike, Lal, Dennis, Lipscombe, Diane, Pan, Jen Q.
Publicado 2021

CaBLAM! A high-contrast bioluminescent Ca(2+) indicator derived from an engineered Oplophorus gracilirostris luciferase

por Lambert, Gerard G., Crespo, Emmanuel L., Murphy, Jeremy, Boassa, Daniela, Luong, Selena, Celinskis, Dmitrijs, Venn, Stephanie, Hu, Junru, Sprecher, Brittany, Tree, Maya O., Orcutt, Richard, Heydari, Daniel, Bell, Aidan B., Torreblanca-Zanca, Albertina, Hakimi, Ali, Lipscombe, Diane, Moore, Christopher I., Hochgeschwender, Ute, Shaner, Nathan C.
Publicado 2023

Framework for advancing rigorous research

por Koroshetz, Walter J, Behrman, Shannon, Brame, Cynthia J, Branchaw, Janet L, Brown, Emery N, Clark, Erin A, Dockterman, David, Elm, Jordan J, Gay, Pamela L, Green, Katelyn M, Hsi, Sherry, Kaplitt, Michael G, Kolber, Benedict J, Kolodkin, Alex L, Lipscombe, Diane, MacLeod, Malcolm R, McKinney, Caleb C, Munafò, Marcus R, Oakley, Barbara, Olimpo, Jeffrey T, Percie du Sert, Nathalie, Raman, Indira M, Riley, Ceri, Shelton, Amy L, Uzzo, Stephen Miles, Crawford, Devon C, Silberberg, Shai D
Publicado 2020