Driving fibrosis in neuromuscular diseases: Role and regulation of Connective tissue growth factor (CCN2/CTGF)

por Rebolledo, Daniela L., Lipson, Kenneth E., Brandan, Enrique
Publicado 2021

CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis

por Lipson, Kenneth E, Wong, Carol, Teng, Yuchin, Spong, Suzanne
Publicado 2012

Anti-connective tissue growth factor (CTGF/CCN2) monoclonal antibody attenuates skin fibrosis in mice models of systemic sclerosis

por Makino, Katsunari, Makino, Tomoko, Stawski, Lukasz, Lipson, Kenneth E., Leask, Andrew, Trojanowska, Maria
Publicado 2017

Late treatment with imatinib mesylate ameliorates radiation-induced lung fibrosis in a mouse model

por Li, Minglun, Abdollahi, Amir, Gröne, Hermann-Josef, Lipson, Kenneth E, Belka, Claus, Huber, Peter E
Publicado 2009

Comparison of human B cell activation by TLR7 and TLR9 agonists

por Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Alkan, Sefik S, Birmachu, Woubalem
Publicado 2008

Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists

por Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, Nikolsky, Yuri
Publicado 2007

Analysis of longitudinal semicontinuous data using marginalized two-part model

por Jaffa, Miran A., Gebregziabher, Mulugeta, Garrett, Sara M., Luttrell, Deirdre K., Lipson, Kenneth E., Luttrell, Louis M., Jaffa, Ayad A.
Publicado 2018

Oncogene addiction and radiation oncology: effect of radiotherapy with photons and carbon ions in ALK-EML4 translocated NSCLC

por Dai, Ying, Wei, Quanxiang, Schwager, Christian, Hanne, Janina, Zhou, Cheng, Herfarth, Klaus, Rieken, Stefan, Lipson, Kenneth E., Debus, Jürgen, Abdollahi, Amir
Publicado 2018

Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab

por Sternlicht, Mark D., Wirkner, Ute, Bickelhaupt, Sebastian, Lopez Perez, Ramon, Tietz, Alexandra, Lipson, Kenneth E., Seeley, Todd W., Huber, Peter E.
Publicado 2018

Vascular Endothelial Cell-Specific Connective Tissue Growth Factor (CTGF) Is Necessary for Development of Chronic Hypoxia-Induced Pulmonary Hypertension

por Pi, Liya, Fu, Chunhua, Lu, Yuanquing, Zhou, Junmei, Jorgensen, Marda, Shenoy, Vinayak, Lipson, Kenneth E., Scott, Edward W., Bryant, Andrew J.
Publicado 2018

Small molecule receptor tyrosine kinase inhibitor of platelet-derived growth factor signaling (SU9518) modifies radiation response in fibroblasts and endothelial cells

por Li, Minglun, Ping, Gong, Plathow, Christian, Trinh, Thuy, Lipson, Kenneth E, Hauser, Kai, Krempien, Robert, Debus, Juergen, Abdollahi, Amir, Huber, Peter E
Publicado 2006

Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis

por Abdollahi, Amir, Li, Minglun, Ping, Gong, Plathow, Christian, Domhan, Sophie, Kiessling, Fabian, Lee, Leslie B., McMahon, Gerald, Gröne, Hermann-Josef, Lipson, Kenneth E., Huber, Peter E.
Publicado 2005

Connective tissue growth factor-specific monoclonal antibody inhibits growth of malignant mesothelioma in an orthotopic mouse model

por Ohara, Yuuki, Chew, Shan Hwu, Misawa, Nobuaki, Wang, Shenqi, Somiya, Daiki, Nakamura, Kae, Kajiyama, Hiroaki, Kikkawa, Fumitaka, Tsuyuki, Yuta, Jiang, Li, Yamashita, Kyoko, Sekido, Yoshitaka, Lipson, Kenneth E., Toyokuni, Shinya
Publicado 2018

Radiotherapy combined with TLR7/8 activation induces strong immune responses against gastrointestinal tumors

por Schölch, Sebastian, Rauber, Conrad, Tietz, Alexandra, Rahbari, Nuh N., Bork, Ulrich, Schmidt, Thomas, Kahlert, Christoph, Haberkorn, Uwe, Tomai, Mark A., Lipson, Kenneth E., Carretero, Rafael, Weitz, Jürgen, Koch, Moritz, Huber, Peter E.
Publicado 2014

Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis

por Sakai, Norihiko, Nakamura, Miki, Lipson, Kenneth E., Miyake, Taito, Kamikawa, Yasutaka, Sagara, Akihiro, Shinozaki, Yasuyuki, Kitajima, Shinji, Toyama, Tadashi, Hara, Akinori, Iwata, Yasunori, Shimizu, Miho, Furuichi, Kengo, Kaneko, Shuichi, Tager, Andrew M., Wada, Takashi
Publicado 2017

FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition

por Brenner, Mitchell C., Krzyzanski, Wojciech, Chou, James Z., Signore, Pierre E., Fung, Cyra K., Guzman, David, Li, Dongxia, Zhang, Weihua, Olsen, David R., Nguyen, Viet-Tam L., Koo, Carolyn W., Sternlicht, Mark D., Lipson, Kenneth E.
Publicado 2016

Connective Tissue Growth Factor Inhibition Enhances Cardiac Repair and Limits Fibrosis After Myocardial Infarction

por Vainio, Laura E., Szabó, Zoltán, Lin, Ruizhu, Ulvila, Johanna, Yrjölä, Raisa, Alakoski, Tarja, Piuhola, Jarkko, Koch, Walter J., Ruskoaho, Heikki, Fouse, Shaun D., Seeley, Todd W., Gao, Erhe, Signore, Pierre, Lipson, Kenneth E., Magga, Johanna, Kerkelä, Risto
Publicado 2019

Towards better definition, quantification and treatment of fibrosis in heart failure. A scientific roadmap by the Committee of Translational Research of the Heart Failure Associati...

por de Boer, Rudolf A., De Keulenaer, Gilles, Bauersachs, Johann, Brutsaert, Dirk, Cleland, John G., Diez, Javier, Du, Xiao‐Jun, Ford, Paul, Heinzel, Frank R., Lipson, Kenneth E., McDonagh, Theresa, Lopez‐Andres, Natalia, Lunde, Ida G., Lyon, Alexander R., Pollesello, Piero, Prasad, Sanjay K., Tocchetti, Carlo G., Mayr, Manuel, Sluijter, Joost P.G., Thum, Thomas, Tschöpe, Carsten, Zannad, Faiez, Zimmermann, Wolfram‐Hubertus, Ruschitzka, Frank, Filippatos, Gerasimos, Lindsey, Merry L., Maack, Christoph, Heymans, Stephane
Publicado 2019