Model-Based Approach for Optimizing Ceftobiprole Dosage in Pediatric Patients

por Rubino, Christopher M., Cammarata, Anthony P., Smits, Anne, Schröpf, Sebastian, Polak, Mark, Litherland, Karine, Hamed, Kamal
Publicado 2021

2561. Population Pharmacokinetic Analyses for Ceftobiprole Using Data from Phase 1 and 3 Studies

por Cammarata, Anthony P, Litherland, Karine, Safir, M Courtney, Bhavnani, Sujata M, Saulay, Mikael, Smart, Jennifer, Jones, Mark E, Engelhardt, Marc, Rubino, Christopher M
Publicado 2023

ADME studies of [5‐(3)H]‐2′‐O‐methyluridine nucleoside in mice: a building block in siRNA therapeutics

por Lozac'h, Frederic, Christensen, Jesper, Faller, Thomas, van de Kerkhof, Esther, Krauser, Joel, Garnier, Maxime, Litherland, Karine, Catoire, Alexandre, Natt, Francois, Hunziker, Jurg, Swart, Piet
Publicado 2016

Ceftobiprole Medocaril Is an Effective Post-Exposure Treatment in the Fischer 344 Rat Model of Pneumonic Tularemia

por Hahn, Mark M., Triplett, Cheryl A., Anderson, Michael S., Smart, Jennifer I., Litherland, Karine, Keech, Stephen, von Siebenthal, Franziska, Jones, Mark, Phipps, Andrew J., Henning, Lisa N.
Publicado 2023

2530. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Ceftobiprole Dose Selection for the Treatment of Patients with Acute Bacterial Skin and Skin Str...

por Bhavnani, Sujata M, Hammel, Jeffrey P, Rinaldo, Anthony J, Smart, Jennifer, Litherland, Karine, Duncan, Leonard R, Jones, Mark E, Engelhardt, Marc, Ambrose, Paul G, Rubino, Christopher M
Publicado 2023

2531. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Ceftobiprole Dosing Regimens for Patients with Staphylococcus aureus Bacteremia (SAB)

por Bhavnani, Sujata M, Hammel, Jeffrey P, Rinaldo, Anthony J, Smart, Jennifer, Litherland, Karine, Duncan, Leonard R, Jones, Mark E, Engelhardt, Marc, Ambrose, Paul G, Rubino, Christopher M
Publicado 2023

2532. Pharmacokinetic-Pharmacodynamic Analyses for Ceftobiprole Efficacy Based on Phase 3 Data from Patients with Staphylococcus aureus Bacteremia

por Bhavnani, Sujata M, Hammel, Jeffrey P, Liolios, Kathryn, Cammarata, Anthony P, Saulay, Mikael, Rubino, Christopher M, Engelhardt, Marc, Smart, Jennifer, Jones, Mark E, Ambrose, Paul G, Litherland, Karine
Publicado 2023

Pharmacokinetics and Safety of Ceftobiprole in Pediatric Patients

por Rubino, Christopher M., Polak, Mark, Schröpf, Sebastian, Münch, Hans Georg, Smits, Anne, Cossey, Veerle, Tomasik, Tomasz, Kwinta, Przemko, Snariene, Rima, Liubsys, Arunas, Gardovska, Dace, Hornik, Chi Dang, Bosheva, Miroslava, Ruehle, Christine, Litherland, Karine, Hamed, Kamal
Publicado 2021

Whole-body scanning PCR; a highly sensitive method to study the biodistribution of mRNAs, noncoding RNAs and therapeutic oligonucleotides

por Boos, Julien A., Kirk, David W., Piccolotto, Mari-Luz, Zuercher, Werner, Gfeller, Sandro, Neuner, Philippe, Dattler, Andre, Wishart, William L., Von Arx, Fabian, Beverly, Michael, Christensen, Jesper, Litherland, Karine, van de Kerkhof, Esther, Swart, Pieter J., Faller, Thomas, Beyerbach, Armin, Morrissey, David, Hunziker, Juerg, Beuvink, Iwan
Publicado 2013