Kidney organoids: accurate models or fortunate accidents

por Little, Melissa H., Combes, Alexander N.
Publicado 2019

Defining the Molecular Character of the Developing and Adult Kidney Podocyte

por Brunskill, Eric W., Georgas, Kylie, Rumballe, Bree, Little, Melissa H., Potter, S. Steven
Publicado 2011

Analysed cap mesenchyme track data from live imaging of mouse kidney development

por Lefevre, James G., Combes, Alexander N., Little, Melissa H., Hamilton, Nicholas A.
Publicado 2016

Single-cell analysis reveals congruence between kidney organoids and human fetal kidney

por Combes, Alexander N., Zappia, Luke, Er, Pei Xuan, Oshlack, Alicia, Little, Melissa H.
Publicado 2019

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis

por Lambert, Ben, MacLean, Adam L., Fletcher, Alexander G., Combes, Alexander N., Little, Melissa H., Byrne, Helen M.
Publicado 2018

Nephron progenitor commitment is a stochastic process influenced by cell migration

por Lawlor, Kynan T, Zappia, Luke, Lefevre, James, Park, Joo-Seop, Hamilton, Nicholas A, Oshlack, Alicia, Little, Melissa H, Combes, Alexander N
Publicado 2019

DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets

por Wilson, Sean B., Howden, Sara E., Vanslambrouck, Jessica M., Dorison, Aude, Alquicira-Hernandez, Jose, Powell, Joseph E., Little, Melissa H.
Publicado 2022

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

por Howden, Sara E., McColl, Bradley, Glaser, Astrid, Vadolas, Jim, Petrou, Steven, Little, Melissa H., Elefanty, Andrew G., Stanley, Edouard G.
Publicado 2016

Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration

por Short, Kieran M, Combes, Alexander N, Lisnyak, Valerie, Lefevre, James G, Jones, Lynelle K, Little, Melissa H, Hamilton, Nicholas A, Smyth, Ian M
Publicado 2018

Multivariate patterning of human pluripotent cells under perfusion reveals critical roles of induced paracrine factors in kidney organoid development

por Glass, Nick R., Takasako, Minoru, Er, Pei Xuan, Titmarsh, Drew M., Hidalgo, Alejandro, Wolvetang, Ernst J., Little, Melissa H., Cooper-White, Justin J.
Publicado 2020

M2 macrophage polarisation is associated with alveolar formation during postnatal lung development

por Jones, Christina V, Williams, Timothy M, Walker, Kenneth A, Dickinson, Hayley, Sakkal, Samy, Rumballe, Bree A, Little, Melissa H, Jenkin, Graham, Ricardo, Sharon D
Publicado 2013

Evaluation of biomarkers for in vitro prediction of drug-induced nephrotoxicity: comparison of HK-2, immortalized human proximal tubule epithelial, and primary cultures of human pr...

por Huang, Johnny X, Kaeslin, Geraldine, Ranall, Max V, Blaskovich, Mark A, Becker, Bernd, Butler, Mark S, Little, Melissa H, Lash, Lawrence H, Cooper, Matthew A
Publicado 2015

Identification of Anchor Genes during Kidney Development Defines Ontological Relationships, Molecular Subcompartments and Regulatory Pathways

por Thiagarajan, Rathi D., Georgas, Kylie M., Rumballe, Bree A., Lesieur, Emmanuelle, Chiu, Han Sheng, Taylor, Darrin, Tang, Dave T. P., Grimmond, Sean M., Little, Melissa H.
Publicado 2011

Crim1 has cell-autonomous and paracrine roles during embryonic heart development

por Iyer, Swati, Chou, Fang Yu, Wang, Richard, Chiu, Han Sheng, Raju, Vinay K. Sundar, Little, Melissa H., Thomas, Walter G., Piper, Michael, Pennisi, David J.
Publicado 2016

Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

por Kumar, Santhosh V., Er, Pei X., Lawlor, Kynan T., Motazedian, Ali, Scurr, Michelle, Ghobrial, Irene, Combes, Alexander N., Zappia, Luke, Oshlack, Alicia, Stanley, Edouard G., Little, Melissa H.
Publicado 2019

Identification of Novel Markers of Mouse Fetal Ovary Development

por Chen, Huijun, Palmer, James S., Thiagarajan, Rathi D., Dinger, Marcel E., Lesieur, Emmanuelle, Chiu, Hansheng, Schulz, Alexandra, Spiller, Cassy, Grimmond, Sean M., Little, Melissa H., Koopman, Peter, Wilhelm, Dagmar
Publicado 2012

Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures

por Cerruti, Benedetta, Puliafito, Alberto, Shewan, Annette M., Yu, Wei, Combes, Alexander N., Little, Melissa H., Chianale, Federica, Primo, Luca, Serini, Guido, Mostov, Keith E., Celani, Antonio, Gamba, Andrea
Publicado 2013

Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids

por Vanslambrouck, Jessica M., Wilson, Sean B., Tan, Ker Sin, Groenewegen, Ella, Rudraraju, Rajeev, Neil, Jessica, Lawlor, Kynan T., Mah, Sophia, Scurr, Michelle, Howden, Sara E., Subbarao, Kanta, Little, Melissa H.
Publicado 2022

Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids

por Vanslambrouck, Jessica M., Wilson, Sean B., Tan, Ker Sin, Groenewegen, Ella, Rudraraju, Rajeev, Neil, Jessica, Lawlor, Kynan T., Mah, Sophia, Scurr, Michelle, Howden, Sara E., Subbarao, Kanta, Little, Melissa H.
Publicado 2022

An In Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development

por Knarston, Ingrid M., Pachernegg, Svenja, Robevska, Gorjana, Ghobrial, Irene, Er, Pei Xuan, Georges, Elizabeth, Takasato, Minoru, Combes, Alexander N., Jørgensen, Anne, Little, Melissa H., Sinclair, Andrew H., Ayers, Katie L.
Publicado 2020