Site-Specific Conversion of Cysteine in a Protein to Dehydroalanine Using 2-Nitro-5-thiocyanatobenzoic Acid

por Qiao, Yuchen, Yu, Ge, Leeuwon, Sunshine Z., Liu, Wenshe Ray
Publicado 2021

An Enhanced Hybrid Screening Approach to Identify Potent Inhibitors for the SARS-CoV-2 Main Protease From the NCI Compound Library

por Li, Shuhua G., Yang, Kai S., Blankenship, Lauren R., Cho, Chia-Chuan D., Xu, Shiqing, Wang, Hongbin, Liu, Wenshe Ray
Publicado 2022

The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS

por Zhao, Baoyu, Xu, Pengbiao, Rowlett, Chesley M., Jing, Tao, Shinde, Omkar, Lei, Yuanjiu, West, A. Phillip, Liu, Wenshe Ray, Li, Pingwei
Publicado 2020

Bepridil is potent against SARS-CoV-2 In Vitro

por Vatansever, Erol C., Yang, Kai, Kratch, Kaci C., Drelich, Aleksandra, Cho, Chia-Chuan, Mellott, Drake M., Xu, Shiqing, Tseng, Chien-Te K., Liu, Wenshe Ray
Publicado 2020

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease

por Yang, Kai S., Alex Kuo, Syuan-Ting, Blankenship, Lauren R., Geng, Zhi Zachary, Li, Shuhua G., Russell, David H., Yan, Xin, Xu, Shiqing, Liu, Wenshe Ray
Publicado 2022

An amber obligate active site-directed ligand evolution technique for phage display

por Tharp, Jeffery M., Hampton, J. Trae, Reed, Catrina A., Ehnbom, Andreas, Chen, Peng-Hsun Chase, Morse, Jared S., Kurra, Yadagirri, Pérez, Lisa M., Xu, Shiqing, Liu, Wenshe Ray
Publicado 2020

An amber-encoding helper phage for more efficient phage display of noncanonical amino acids

por Hampton, Joshua Trae, Cho, Chia-Chuan Dean, Coleman, Demonta D, Geng, Zhi Zachary, Chen, Peng-Hsun Chase, Dubey, Gopal K, Sylvain, Lauralee D, Xu, Shiqing, Liu, Wenshe Ray
Publicado 2023

Bepridil is potent against SARS-CoV-2 in vitro

por Vatansever, Erol C., Yang, Kai S., Drelich, Aleksandra K., Kratch, Kaci C., Cho, Chia-Chuan, Kempaiah, Kempaiah Rayavara, Hsu, Jason C., Mellott, Drake M., Xu, Shiqing, Tseng, Chien-Te K., Liu, Wenshe Ray
Publicado 2021

A multi-pronged evaluation of aldehyde-based tripeptidyl main protease inhibitors as SARS-CoV-2 antivirals

por Ma, Yuying, Yang, Kai S., Geng, Zhi Zachary, Alugubelli, Yugendar R., Shaabani, Namir, Vatansever, Erol C., Ma, Xinyu R., Cho, Chia-Chuan, Khatua, Kaustav, Xiao, Jing, Blankenship, Lauren R., Yu, Ge, Sankaran, Banumathi, Li, Pingwei, Allen, Robert, Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray
Publicado 2022

A systematic exploration of boceprevir-based main protease inhibitors as SARS-CoV-2 antivirals

por Alugubelli, Yugendar R., Geng, Zhi Zachary, Yang, Kai S., Shaabani, Namir, Khatua, Kaustav, Ma, Xinyu R., Vatansever, Erol C., Cho, Chia-Chuan, Ma, Yuying, Xiao, Jing, Blankenship, Lauren R., Yu, Ge, Sankaran, Banumathi, Li, Pingwei, Allen, Robert, Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray
Publicado 2022

Evaluation of SARS-CoV-2 Main Protease Inhibitors Using a Novel Cell-Based Assay

por Cao, Wenyue, Cho, Chia-Chuan Dean, Geng, Zhi Zachary, Shaabani, Namir, Ma, Xinyu R., Vatansever, Erol C., Alugubelli, Yugendar R., Ma, Yuying, Chaki, Sankar P., Ellenburg, William H., Yang, Kai S., Qiao, Yuchen, Allen, Robert, Neuman, Benjamin W., Ji, Henry, Xu, Shiqing, Liu, Wenshe Ray
Publicado 2022