Development of an improved inhibitor of Lats kinases to promote regeneration of mammalian organs

por Kastan, Nathaniel R., Oak, Sanyukta, Liang, Rui, Baxt, Leigh, Myers, Robert W., Ginn, John, Liverton, Nigel, Huggins, David J., Pichardo, John, Paul, Matthew, Carroll, Thomas S., Nagiel, Aaron, Gnedeva, Ksenia, Hudspeth, A. J.
Publicado 2022

Preclinical pharmacology and pharmacokinetics of CERC‐301, a GluN2B‐selective N‐methyl‐D‐aspartate receptor antagonist

por Garner, Rachel, Gopalakrishnan, Shobha, McCauley, John A., Bednar, Rodney A., Gaul, Stanley L., Mosser, Scott D., Kiss, Laszlo, Lynch, Joseph J., Patel, Shil, Fandozzi, Christine, Lagrutta, Armando, Briscoe, Richard, Liverton, Nigel J., Paterson, Blake M., Vornov, James J., Mazhari, Reza
Publicado 2015

Whole Cell Active Inhibitors of Mycobacterial Lipoamide Dehydrogenase Afford Selectivity over the Human Enzyme through Tight Binding Interactions

por Ginn, John, Jiang, Xiuju, Sun, Shan, Michino, Mayako, Huggins, David J., Mbambo, Zodwa, Jansen, Robert, Rhee, Kyu Y., Arango, Nancy, Lima, Christopher D., Liverton, Nigel, Imaeda, Toshihiro, Okamoto, Rei, Kuroita, Takanobu, Aso, Kazuyoshi, Stamford, Andrew, Foley, Michael, Meinke, Peter T., Nathan, Carl, Bryk, Ruslana
Publicado 2021

Small-Molecule Inhibition of the Acyl-Lysine Reader ENL as a Strategy against Acute Myeloid Leukemia

por Liu, Yiman, Li, Qinglan, Alikarami, Fatemeh, Barrett, Declan R., Mahdavi, Leila, Li, Hangpeng, Tang, Sylvia, Khan, Tanweer A., Michino, Mayako, Hill, Connor, Song, Lele, Yang, Lu, Li, Yuanyuan, Pokharel, Sheela Pangeni, Stamford, Andrew W., Liverton, Nigel, Renzetti, Louis M., Taylor, Simon, Watt, Gillian F., Ladduwahetty, Tammy, Kargman, Stacia, Meinke, Peter T., Foley, Michael A., Shi, Junwei, Li, Haitao, Carroll, Martin, Chen, Chun-Wei, Gardini, Alessandro, Maillard, Ivan, Huggins, David J., Bernt, Kathrin M., Wan, Liling
Publicado 2022