STAT3 Activation in Combination with NF-KappaB Inhibition Induces Tolerogenic Dendritic Cells with High Therapeutic Potential to Attenuate Collagen-Induced Arthritis

por Prado, Carolina, Ugalde, Valentina, González, Hugo, Figueroa, Alicia, López, Ernesto, Lladser, Alvaro, Pacheco, Rodrigo
Publicado 2019

IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8(+) T Cell Priming

por Medel, Bernardita, Costoya, Cristobal, Fernandez, Dominique, Pereda, Cristian, Lladser, Alvaro, Sauma, Daniela, Pacheco, Rodrigo, Iwawaki, Takao, Salazar-Onfray, Flavio, Osorio, Fabiola
Publicado 2019

Small Extracellular Vesicles Released from Ovarian Cancer Spheroids in Response to Cisplatin Promote the Pro-Tumorigenic Activity of Mesenchymal Stem Cells

por Vera, Nelly, Acuña-Gallardo, Stephanie, Grünenwald, Felipe, Caceres-Verschae, Albano, Realini, Ornella, Acuña, Rodrigo, Lladser, Alvaro, Illanes, Sebastián E., Varas-Godoy, Manuel
Publicado 2019

Dopaminergic Signalling Enhances IL-2 Production and Strengthens Anti-Tumour Response Exerted by Cytotoxic T Lymphocytes in a Melanoma Mouse Model

por Chovar-Vera, Ornella, López, Ernesto, Gálvez-Cancino, Felipe, Prado, Carolina, Franz, Dafne, Figueroa, Diego A., Espinoza, Alexandra, Figueroa, Claudio, Lladser, Alvaro, Pacheco, Rodrigo
Publicado 2022

The Heteromeric Complex Formed by Dopamine Receptor D(5) and CCR9 Leads the Gut Homing of CD4(+) T Cells Upon Inflammation

por Osorio-Barrios, Francisco, Navarro, Gemma, Campos, Javier, Ugalde, Valentina, Prado, Carolina, Raïch, Iu, Contreras, Francisco, López, Ernesto, Espinoza, Alexandra, Lladser, Alvaro, Franco, Rafael, Pacheco, Rodrigo
Publicado 2021

Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancer

por Lopez, Ernesto, Hidalgo, Sofía, Roa, Eduardo, Gómez, Javiera, Hermansen Truan, Carlos, Sanders, Evy, Carrasco, Cristian, Pacheco, Rodrigo, Salazar-Onfray, Flavio, Varas-Godoy, Manuel, Borgna, Vincenzo, Lladser, Alvaro
Publicado 2023

Tissue-resident memory CD8(+) T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells

por Menares, Evelyn, Gálvez-Cancino, Felipe, Cáceres-Morgado, Pablo, Ghorani, Ehsan, López, Ernesto, Díaz, Ximena, Saavedra-Almarza, Juan, Figueroa, Diego A., Roa, Eduardo, Quezada, Sergio A., Lladser, Alvaro
Publicado 2019

Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia

por Sanhueza, Carlos, Bennett, Jimena Castillo, Valenzuela-Valderrama, Manuel, Contreras, Pamela, Lobos-González, Lorena, Campos, América, Wehinger, Sergio, Lladser, Álvaro, Kiessling, Rolf, Leyton, Lisette, Quest, Andrew F.G.
Publicado 2020

Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Auto...

por Prado, Carolina, Gaiazzi, Michela, González, Hugo, Ugalde, Valentina, Figueroa, Alicia, Osorio-Barrios, Francisco J., López, Ernesto, Lladser, Alvaro, Rasini, Emanuela, Marino, Franca, Zaffaroni, Mauro, Cosentino, Marco, Pacheco, Rodrigo
Publicado 2018

Immunotherapeutic Potential of Mollusk Hemocyanins in Combination with Human Vaccine Adjuvants in Murine Models of Oral Cancer

por Mora Román, Juan José, Del Campo, Miguel, Villar, Javiera, Paolini, Francesca, Curzio, Gianfranca, Venuti, Aldo, Jara, Lilian, Ferreira, Jorge, Murgas, Paola, Lladser, Alvaro, Manubens, Augusto, Becker, María Inés
Publicado 2019

In Vitro-Generated Tc17 Cells Present a Memory Phenotype and Serve As a Reservoir of Tc1 Cells In Vivo

por Flores-Santibáñez, Felipe, Cuadra, Bárbara, Fernández, Dominique, Rosemblatt, Mariana V., Núñez, Sarah, Cruz, Pablo, Gálvez-Cancino, Felipe, Cárdenas, J. César, Lladser, Alvaro, Rosemblatt, Mario, Bono, María Rosa, Sauma, Daniela
Publicado 2018

Vaccination-induced skin-resident memory CD8(+) T cells mediate strong protection against cutaneous melanoma

por Gálvez-Cancino, Felipe, López, Ernesto, Menares, Evelyn, Díaz, Ximena, Flores, Camila, Cáceres, Pablo, Hidalgo, Sofía, Chovar, Ornella, Alcántara-Hernández, Marcela, Borgna, Vincenzo, Varas-Godoy, Manuel, Salazar-Onfray, Flavio, Idoyaga, Juliana, Lladser, Alvaro
Publicado 2018

Ecto-5′-Nucleotidase (CD73) Regulates the Survival of CD8+ T Cells

por Rosemblatt, Mariana V., Parra-Tello, Brian, Briceño, Pedro, Rivas-Yáñez, Elizabeth, Tucer, Suat, Saavedra-Almarza, Juan, Hörmann, Pilar, Martínez, Brandon A., Lladser, Álvaro, Rosemblatt, Mario, Cekic, Caglar, Bono, María Rosa, Sauma, Daniela
Publicado 2021

Nuanced role for dendritic cell intrinsic IRE1 RNase in the regulation of antitumor adaptive immunity

por Flores-Santibañez, Felipe, Rennen, Sofie, Fernández, Dominique, De Nolf, Clint, Van De Velde, Evelien, Gaete González, Sandra, Fuentes, Camila, Moreno, Carolina, Figueroa, Diego, Lladser, Álvaro, Iwawaki, Takao, Bono, María Rosa, Janssens, Sophie, Osorio, Fabiola
Publicado 2023

Caveolin-1 Expression Increases upon Maturation in Dendritic Cells and Promotes Their Migration to Lymph Nodes Thereby Favoring the Induction of CD8(+) T Cell Responses

por Oyarce, Cesar, Cruz-Gomez, Sebastián, Galvez-Cancino, Felipe, Vargas, Pablo, Moreau, Hélène D., Diaz-Valdivia, Natalia, Diaz, Jorge, Salazar-Onfray, Flavio Andres, Pacheco, Rodrigo, Lennon-Dumenil, Ana Maria, Quest, Andrew F. G., Lladser, Alvaro
Publicado 2017

CD73 Ectonucleotidase Restrains CD8+ T Cell Metabolic Fitness and Anti-tumoral Activity

por Briceño, Pedro, Rivas-Yañez, Elizabeth, Rosemblatt, Mariana V., Parra-Tello, Brian, Farías, Paula, Vargas, Leonardo, Simon, Valeska, Cárdenas, César, Lladser, Alvaro, Salazar-Onfray, Flavio, Elorza, Alvaro A., Rosemblatt, Mario, Bono, María Rosa, Sauma, Daniela
Publicado 2021

Transcriptional and Functional Analysis of CD1c(+) Human Dendritic Cells Identifies a CD163(+) Subset Priming CD8(+)CD103(+) T Cells

por Bourdely, Pierre, Anselmi, Giorgio, Vaivode, Kristine, Ramos, Rodrigo Nalio, Missolo-Koussou, Yoann, Hidalgo, Sofia, Tosselo, Jimena, Nuñez, Nicolas, Richer, Wilfrid, Vincent-Salomon, Anne, Saxena, Alka, Wood, Kristie, Lladser, Alvaro, Piaggio, Eliane, Helft, Julie, Guermonprez, Pierre
Publicado 2020

Purinergic Signaling as a Regulator of Th17 Cell Plasticity

por Fernández, Dominique, Flores-Santibáñez, Felipe, Neira, Jocelyn, Osorio-Barrios, Francisco, Tejón, Gabriela, Nuñez, Sarah, Hidalgo, Yessia, Fuenzalida, Maria Jose, Meza, Daniel, Ureta, Gonzalo, Lladser, Alvaro, Pacheco, Rodrigo, Acuña-Castillo, Claudio, Guixé, Victoria, Quintana, Francisco J., Bono, Maria Rosa, Rosemblatt, Mario, Sauma, Daniela
Publicado 2016

Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation

por Arce, Maximiliano, Pinto, Mauricio P., Galleguillos, Macarena, Muñoz, Catalina, Lange, Soledad, Ramirez, Carolina, Erices, Rafaela, Gonzalez, Pamela, Velasquez, Ethel, Tempio, Fabián, Lopez, Mercedes N., Salazar-Onfray, Flavio, Cautivo, Kelly, Kalergis, Alexis M., Cruz, Sebastián, Lladser, Álvaro, Lobos-González, Lorena, Valenzuela, Guillermo, Olivares, Nixa, Sáez, Claudia, Koning, Tania, Sánchez, Fabiola A., Fuenzalida, Patricia, Godoy, Alejandro, Contreras Orellana, Pamela, Leyton, Lisette, Lugano, Roberta, Dimberg, Anna, Quest, Andrew F.G., Owen, Gareth I.
Publicado 2019