Identifying a Minor Histocompatibility Antigen in Mauritian Cynomolgus Macaques Encoded by APOBEC3C

por Weinfurter, Jason T., Graham, Michael E., Ericsen, Adam J., Matschke, Lea M., Llewellyn-Lacey, Sian, Price, David A., Wiseman, Roger W., Reynolds, Matthew R.
Publicado 2020

Ageing Curtails the Diversity and Functionality of Nascent CD8(+) T Cell Responses against SARS-CoV-2

por Proietto, Davide, Dallan, Beatrice, Gallerani, Eleonora, Albanese, Valentina, Llewellyn-Lacey, Sian, Price, David A., Appay, Victor, Pacifico, Salvatore, Caputo, Antonella, Nicoli, Francesco, Gavioli, Riccardo
Publicado 2023

Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines

por Nicoli, Francesco, Pacifico, Salvatore, Gallerani, Eleonora, Marzola, Erika, Albanese, Valentina, Finessi, Valentina, Llewellyn-Lacey, Sian, Price, David A., Appay, Victor, Marconi, Peggy, Guerrini, Remo, Caputo, Antonella, Gavioli, Riccardo
Publicado 2021

The superantigens SpeC and TSST-1 specifically activate TRBV12-3/12-4(+) memory T cells

por Shepherd, Freya R., Davies, Kate, Miners, Kelly L., Llewellyn-Lacey, Sian, Kollnberger, Simon, Redman, James E., Grant, Melissa M., Ladell, Kristin, Price, David A., McLaren, James E.
Publicado 2023

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma

por Tauber, Catrin, Schultheiss, Michael, Luca, Raffaele De, Buettner, Nico, Llewellyn-Lacey, Sian, Emmerich, Florian, Zehe, Sebastian, Price, David A., Neumann-Haefelin, Christoph, Schmitt-Graeff, Annette, Hofmann, Maike, Thimme, Robert
Publicado 2019

Cellular-Level Versus Receptor-Level Response Threshold Hierarchies in T-Cell Activation

por van den Berg, Hugo A., Ladell, Kristin, Miners, Kelly, Laugel, Bruno, Llewellyn-Lacey, Sian, Clement, Mathew, Cole, David K., Gostick, Emma, Wooldridge, Linda, Sewell, Andrew K., Bridgeman, John S., Price, David A.
Publicado 2013

A Single Autoimmune T Cell Receptor Recognizes More Than a Million Different Peptides

por Wooldridge, Linda, Ekeruche-Makinde, Julia, van den Berg, Hugo A., Skowera, Anna, Miles, John J., Tan, Mai Ping, Dolton, Garry, Clement, Mathew, Llewellyn-Lacey, Sian, Price, David A., Peakman, Mark, Sewell, Andrew K.
Publicado 2012

Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8(+) T cells in HIV infection

por Cabral-Piccin, Mariela P., Papagno, Laura, Lahaye, Xavier, Perdomo-Celis, Federico, Volant, Stevenn, White, Eoghann, Monceaux, Valérie, Llewellyn-Lacey, Sian, Fromentin, Rémi, Price, David A., Chomont, Nicolas, Manel, Nicolas, Saez-Cirion, Asier, Appay, Victor
Publicado 2023

CD8(+) T-cell specificity is compromised at a defined MHCI/CD8 affinity threshold

por Dockree, Tamsin, Holland, Christopher J, Clement, Mathew, Ladell, Kristin, McLaren, James E, van den Berg, Hugo A, Gostick, Emma, L Miners, Kelly, Llewellyn-Lacey, Sian, Bridgeman, John S, Man, Stephen, Bailey, Mick, Burrows, Scott R, Price, David A, Wooldridge, Linda
Publicado 2017

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8(+) TCR-Vβ(+) expansions

por Lissina, Anna, McLaren, James E., Ilander, Mette, Andersson, Emma I., Lewis, Catherine S., Clement, Mathew, Herman, Andrew, Ladell, Kristin, Llewellyn-Lacey, Sian, Miners, Kelly L., Gostick, Emma, Melenhorst, J. Joseph, Barrett, A. John, Price, David A., Mustjoki, Satu, Wooldridge, Linda
Publicado 2018

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine

por McLaren, James E., Clement, Mathew, Marsden, Morgan, Miners, Kelly L., Llewellyn-Lacey, Sian, Grant, Emma J., Rubina, Anzelika, Gimeno Brias, Silvia, Gostick, Emma, Stacey, Maria A., Orr, Selinda J., Stanton, Richard J., Ladell, Kristin, Price, David A., Humphreys, Ian R.
Publicado 2019

TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection

por Heim, Kathrin, Binder, Benedikt, Sagar, Wieland, Dominik, Hensel, Nina, Llewellyn-Lacey, Sian, Gostick, Emma, Price, David A., Emmerich, Florian, Vingerhoet, Hildegard, Kraft, Anke R M, Cornberg, Markus, Boettler, Tobias, Neumann-Haefelin, Christoph, Zehn, Dietmar, Bengsch, Bertram, Hofmann, Maike, Thimme, Robert
Publicado 2021

CD8 coreceptor-mediated focusing can reorder the agonist hierarchy of peptide ligands recognized via the T cell receptor

por Clement, Mathew, Knezevic, Lea, Dockree, Tamsin, McLaren, James E., Ladell, Kristin, Miners, Kelly L., Llewellyn-Lacey, Sian, Rubina, Anzelika, Francis, Ore, Cole, David K., Sewell, Andrew K., Bridgeman, John S., Price, David A., van den Berg, Hugo A., Wooldridge, Linda
Publicado 2021

Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors

por Szomolay, Barbara, Liu, Jie, Brown, Paul E, Miles, John J, Clement, Mathew, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J, Sewell, Andrew K, Burrows, Scott R, Roederer, Mario, Price, David A, Wooldridge, Linda, van den Berg, Hugo A
Publicado 2016

Altered basal lipid metabolism underlies the functional impairment of naive CD8(+) T cells in elderly humans

por Nicoli, Francesco, Cabral-Piccin, Mariela P., Papagno, Laura, Gallerani, Eleonora, Fusaro, Mathieu, Folcher, Victor, Dubois, Marion, Clave, Emmanuel, Vallet, Hélène, Frere, Justin J., Gostick, Emma, Llewellyn-Lacey, Sian, Price, David A., Toubert, Antoine, Dupré, Loïc, Boddaert, Jacques, Caputo, Antonella, Gavioli, Riccardo, Appay, Victor
Publicado 2022

Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox

por Adamo, Sarah, Gao, Yu, Sekine, Takuya, Mily, Akhirunnesa, Wu, Jinghua, Storgärd, Elisabet, Westergren, Victor, Filén, Finn, Treutiger, Carl-Johan, Sandberg, Johan K., Sällberg, Matti, Bergman, Peter, Llewellyn-Lacey, Sian, Ljunggren, Hans-Gustaf, Price, David A., Ekström, Anna-Mia, Sette, Alessandro, Grifoni, Alba, Buggert, Marcus
Publicado 2023

Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141(+) dendritic cells to activate naïve and memory WT1‐specific CD8(+) T cells

por Pearson, Frances E, Tullett, Kirsteen M, Leal‐Rojas, Ingrid M, Haigh, Oscar L, Masterman, Kelly‐Anne, Walpole, Carina, Bridgeman, John S, McLaren, James E, Ladell, Kristin, Miners, Kelly, Llewellyn‐Lacey, Sian, Price, David A, Tunger, Antje, Schmitz, Marc, Miles, John J, Lahoud, Mireille H, Radford, Kristen J
Publicado 2020

Cell activation-based screening of natively paired human T cell receptor repertoires

por Fahad, Ahmed S., Chung, Cheng Yu, López Acevedo, Sheila N., Boyle, Nicoleen, Madan, Bharat, Gutiérrez-González, Matías F., Matus-Nicodemos, Rodrigo, Laflin, Amy D., Ladi, Rukmini R., Zhou, John, Wolfe, Jacy, Llewellyn-Lacey, Sian, Koup, Richard A., Douek, Daniel C., Balfour, Henry H., Price, David A., DeKosky, Brandon J.
Publicado 2023

Targeted suppression of autoreactive CD8(+) T-cell activation using blocking anti-CD8 antibodies

por Clement, Mathew, Pearson, James A., Gras, Stephanie, van den Berg, Hugo A., Lissina, Anya, Llewellyn-Lacey, Sian, Willis, Mark D., Dockree, Tamsin, McLaren, James E., Ekeruche-Makinde, Julia, Gostick, Emma, Robertson, Neil P., Rossjohn, Jamie, Burrows, Scott R., Price, David A., Wong, F. Susan, Peakman, Mark, Skowera, Ania, Wooldridge, Linda
Publicado 2016

High-affinity CD8 variants enhance the sensitivity of pMHCI antigen recognition via low-affinity TCRs

por Knezevic, Lea, Wachsmann, Tassilo L.A., Francis, Ore, Dockree, Tamsin, Bridgeman, John S., Wouters, Anne, de Wet, Ben, Cole, David K., Clement, Mathew, McLaren, James E., Gostick, Emma, Ladell, Kristin, Llewellyn-Lacey, Sian, Price, David A., van den Berg, Hugo A., Tabi, Zsuzsanna, Sessions, Richard B., Heemskerk, Mirjam H.M., Wooldridge, Linda
Publicado 2023