RPAP3 C-Terminal Domain: A Conserved Domain for the Assembly of R2TP Co-Chaperone Complexes

por Rodríguez, Carlos F., Llorca, Oscar
Publicado 2020

3D architecture of DNA Pol α reveals the functional core of multi-subunit replicative polymerases

por Klinge, Sebastian, Núñez-Ramírez, Rafael, Llorca, Oscar, Pellegrini, Luca
Publicado 2009

Conformational transitions regulate the exposure of a DNA-binding domain in the RuvBL1–RuvBL2 complex

por López-Perrote, Andrés, Muñoz-Hernández, Hugo, Gil, David, Llorca, Oscar
Publicado 2012

Structure of Human Complement C8, a Precursor to Membrane Attack

por Bubeck, Doryen, Roversi, Pietro, Donev, Rossen, Morgan, B. Paul, Llorca, Oscar, Lea, Susan M.
Publicado 2011

The RNA helicase DHX34 functions as a scaffold for SMG1-mediated UPF1 phosphorylation

por Melero, Roberto, Hug, Nele, López-Perrote, Andrés, Yamashita, Akio, Cáceres, Javier F., Llorca, Oscar
Publicado 2016

Three-dimensional model for the isolated recombinant influenza virus polymerase heterotrimer

por Torreira, Eva, Schoehn, Guy, Fernández, Yolanda, Jorba, Núria, Ruigrok, Rob W.H., Cusack, Stephen, Ortín, Juan, Llorca, Oscar
Publicado 2007

Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies

por Morris, Edward P., Rivera-Calzada, Angel, da Fonseca, Paula C. A., Llorca, Oscar, Pearl, Laurence H., Spagnolo, Laura
Publicado 2011

The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors

por Matias, Pedro M., Baek, Sung Hee, Bandeiras, Tiago M., Dutta, Anindya, Houry, Walid A., Llorca, Oscar, Rosenbaum, Jean
Publicado 2015

Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM

por Muñoz-Hernández, Hugo, Pal, Mohinder, Rodríguez, Carlos F., Fernandez-Leiro, Rafael, Prodromou, Chrisostomos, Pearl, Laurence H., Llorca, Oscar
Publicado 2019

Characterization of SMG-9, an essential component of the nonsense-mediated mRNA decay SMG1C complex

por Fernández, Israel S., Yamashita, Akio, Arias-Palomo, Ernesto, Bamba, Yumi, Bartolomé, Ruben A., Canales, M. Angeles, Teixidó, Joaquín, Ohno, Shigeo, Llorca, Oscar
Publicado 2011

TubZ filament assembly dynamics requires the flexible C-terminal tail

por Fuentes-Pérez, Maria E., Núñez-Ramírez, Rafael, Martín-González, Alejandro, Juan-Rodríguez, David, Llorca, Oscar, Moreno-Herrero, Fernando, Oliva, Maria A.
Publicado 2017

CryoEM of RUVBL1–RUVBL2–ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8

por Serna, Marina, González-Corpas, Ana, Cabezudo, Sofía, López-Perrote, Andrés, Degliesposti, Gianluca, Zarzuela, Eduardo, Skehel, J Mark, Muñoz, Javier, Llorca, Oscar
Publicado 2021

BICD2 phosphorylation regulates dynein function and centrosome separation in G2 and M

por Gallisà-Suñé, Núria, Sànchez-Fernàndez-de-Landa, Paula, Zimmermann, Fabian, Serna, Marina, Regué, Laura, Paz, Joel, Llorca, Oscar, Lüders, Jens, Roig, Joan
Publicado 2023

The structures of cytosolic and plastid-located glutamine synthetases from Medicago truncatula reveal a common and dynamic architecture

por Torreira, Eva, Seabra, Ana Rita, Marriott, Hazel, Zhou, Min, Llorca, Óscar, Robinson, Carol V., Carvalho, Helena G., Fernández-Tornero, Carlos, Pereira, Pedro José Barbosa
Publicado 2014

Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex

por López-Perrote, Andrés, Castaño, Raquel, Melero, Roberto, Zamarro, Teresa, Kurosawa, Hitomi, Ohnishi, Tetsuo, Uchiyama, Akiko, Aoyagi, Kyoko, Buchwald, Gretel, Kataoka, Naoyuki, Yamashita, Akio, Llorca, Oscar
Publicado 2016

Structural basis for the inactivation of cytosolic DNA sensing by the vaccinia virus

por Rivera-Calzada, Angel, Arribas-Bosacoma, Raquel, Ruiz-Ramos, Alba, Escudero-Bravo, Paloma, Boskovic, Jasminka, Fernandez-Leiro, Rafael, Oliver, Antony W., Pearl, Laurence H., Llorca, Oscar
Publicado 2022

Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM

por López-Perrote, Andres, Hug, Nele, González-Corpas, Ana, Rodríguez, Carlos F, Serna, Marina, García-Martín, Carmen, Boskovic, Jasminka, Fernandez-Leiro, Rafael, Caceres, Javier F, Llorca, Oscar
Publicado 2020

The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System

por Rivera-Calzada, Angel, Pal, Mohinder, Muñoz-Hernández, Hugo, Luque-Ortega, Juan R., Gil-Carton, David, Degliesposti, Gianluca, Skehel, J. Mark, Prodromou, Chrisostomos, Pearl, Laurence H., Llorca, Oscar
Publicado 2017

Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone

por Pal, Mohinder, Muñoz-Hernandez, Hugo, Bjorklund, Dennis, Zhou, Lihong, Degliesposti, Gianluca, Skehel, J. Mark, Hesketh, Emma L., Thompson, Rebecca F., Pearl, Laurence H., Llorca, Oscar, Prodromou, Chrisostomos
Publicado 2021

Flexible tethering of primase and DNA Pol α in the eukaryotic primosome

por Núñez-Ramírez, Rafael, Klinge, Sebastian, Sauguet, Ludovic, Melero, Roberto, Recuero-Checa, María A., Kilkenny, Mairi, Perera, Rajika L., García-Alvarez, Begoña, Hall, Richard J., Nogales, Eva, Pellegrini, Luca, Llorca, Oscar
Publicado 2011