The oncogenic role of hepatitis delta virus in hepatocellular carcinoma

por Puigvehí, Marc, Moctezuma-Velázquez, Carlos, Villanueva, Augusto, Llovet, Josep M.
Publicado 2019

Non-invasive imaging criteria for the diagnosis of hepatocellular carcinoma in non-cirrhotic patients with chronic hepatitis B

por Moctezuma-Velázquez, Carlos, Lewis, Sara, Lee, Karen, Amodeo, Salvatore, Llovet, Josep M., Schwartz, Myron, Abraldes, Juan G., Villanueva, Augusto
Publicado 2021

Molecular pathogenesis and systemic therapies for hepatocellular carcinoma

por Llovet, Josep M., Pinyol, Roser, Kelley, Robin K., El-Khoueiry, Anthony, Reeves, Helen, Wang, Xin Wei, Gores, Gregory J., Villanueva, Augusto
Publicado 2022

Liver Cancer Disparities in New York City: A Neighborhood View of Risk and Harm Reduction Factors

por Kamath, Geetanjali R., Taioli, Emanuela, N. Egorova, Natalia, Llovet, Josep M., Perumalswami, Ponni V., Weiss, Jeffrey J., Schwartz, Myron, Ewala, Stanley, Bickell, Nina A.
Publicado 2018

Randomized Phase 3 LEAP-012 Study: Transarterial Chemoembolization With or Without Lenvatinib Plus Pembrolizumab for Intermediate-Stage Hepatocellular Carcinoma Not Amenable to Cur...

por Llovet, Josep M., Vogel, Arndt, Madoff, David C., Finn, Richard S., Ogasawara, Sadahisa, Ren, Zhenggang, Mody, Kalgi, Li, Jerry J., Siegel, Abby B., Dubrovsky, Leonid, Kudo, Masatoshi
Publicado 2022

Pattern of progression in advanced hepatocellular carcinoma treated with ramucirumab

por Reig, Maria, Galle, Peter R., Kudo, Masatoshi, Finn, Richard, Llovet, Josep M., Metti, Andrea L., Schelman, William R., Liang, Kun, Wang, Chunxiao, Widau, Ryan C., Abada, Paolo, Zhu, Andrew X.
Publicado 2020

Beta-catenin cleavage enhances transcriptional activation

por Goretsky, Tatiana, Bradford, Emily M., Ye, Qing, Lamping, Olivia F., Vanagunas, Tomas, Moyer, Mary Pat, Keller, Patrick C., Sinh, Preetika, Llovet, Josep M., Gao, Tianyan, She, Qing-Bai, Li, Linheng, Barrett, Terrence A.
Publicado 2018

Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials

por Montal, Robert, Andreu-Oller, Carmen, Bassaganyas, Laia, Esteban-Fabró, Roger, Moran, Sebastián, Montironi, Carla, Moeini, Agrin, Pinyol, Roser, Peix, Judit, Cabellos, Laia, Villanueva, Augusto, Sia, Daniela, Mazzaferro, Vincenzo, Esteller, Manel, Llovet, Josep M.
Publicado 2019

Palbociclib (PD-0332991), a selective CDK4/6 inhibitor, restricts tumour growth in preclinical models of hepatocellular carcinoma

por Bollard, Julien, Miguela, Verónica, Ruiz de Galarreta, Marina, Venkatesh, Anu, Bian, C Billie, Roberto, Mark P, Tovar, Victoria, Sia, Daniela, Molina-Sánchez, Pedro, Nguyen, Christie B, Nakagawa, Shigeki, Llovet, Josep M, Hoshida, Yujin, Lujambio, Amaia
Publicado 2017

Prognostic and Predictive Factors in Patients with Advanced HCC and Elevated Alpha-Fetoprotein Treated with Ramucirumab in Two Randomized Phase III Trials

por Llovet, Josep M., Singal, Amit G., Villanueva, Augusto, Finn, Richard S., Kudo, Masatoshi, Galle, Peter R., Ikeda, Masafumi, Callies, Sophie, McGrath, Louise M., Wang, Chunxiao, Abada, Paolo, Widau, Ryan C., Gonzalez-Gugel, Elena, Zhu, Andrew X.
Publicado 2022

Ramucirumab in the second-line for patients with hepatocellular carcinoma and elevated alpha-fetoprotein: patient-reported outcomes across two randomised clinical trials

por Zhu, Andrew X, Nipp, Ryan D, Finn, Richard S, Galle, Peter R, Llovet, Josep M, Blanc, Jean-Frederic, Okusaka, Takuji, Chau, Ian, Cella, David, Girvan, Allicia, Gable, Jonathon, Bowman, Lee, Wang, Chunxiao, Hsu, Yanzhi, Abada, Paolo B, Kudo, Masatoshi
Publicado 2020

Phase Ib Study of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Hepatocellular Carcinoma

por Finn, Richard S., Ikeda, Masafumi, Zhu, Andrew X., Sung, Max W., Baron, Ari D., Kudo, Masatoshi, Okusaka, Takuji, Kobayashi, Masahiro, Kumada, Hiromitsu, Kaneko, Shuichi, Pracht, Marc, Mamontov, Konstantin, Meyer, Tim, Kubota, Tomoki, Dutcus, Corina E., Saito, Kenichi, Siegel, Abby B., Dubrovsky, Leonid, Mody, Kalgi, Llovet, Josep M.
Publicado 2020

Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer

por Ortiz-Barahona, Vanessa, Soler, Marta, Davalos, Veronica, García-Prieto, Carlos A., Janin, Maxime, Setien, Fernando, Fernández-Rebollo, Irene, Bech-Serra, Joan J., De La Torre, Carolina, Guil, Sonia, Villanueva, Alberto, Zhang, Pei-Hong, Yang, Li, Guarnacci, Marco, Schumann, Ulrike, Preiss, Thomas, Balaseviciute, Ugne, Montal, Robert, Llovet, Josep M., Esteller, Manel
Publicado 2023

R‐spondin 2 Drives Liver Tumor Development in a Yes‐Associated Protein‐Dependent Manner

por Conboy, Caitlin B., Vélez‐Reyes, Germán L., Tschida, Barbara R., Hu, Hsiangyu, Kaufmann, Gabriel, Koes, Nicholas, Keller, Bryant, Alsinet, Clara, Cornellà, Helena, Pinyol, Roser, Abrahante, Juan E., Temiz, Nuri A., Linden, Michael A., Amin, Khalid, Kuka, Timothy P., Keng, Vincent W., Llovet, Josep M., Starr, Timothy K., Largaespada, David A.
Publicado 2019

Serum alpha-fetoprotein and clinical outcomes in patients with advanced hepatocellular carcinoma treated with ramucirumab

por Zhu, Andrew X., Finn, Richard S., Kang, Yoon-Koo, Yen, Chia-Jui, Galle, Peter R., Llovet, Josep M., Assenat, Eric, Brandi, Giovanni, Motomura, Kenta, Ohno, Izumi, Daniele, Bruno, Vogel, Arndt, Yamashita, Tatsuya, Hsu, Chih-Hung, Gerken, Guido, Bilbruck, John, Hsu, Yanzhi, Liang, Kun, Widau, Ryan C., Wang, Chunxiao, Abada, Paolo, Kudo, Masatoshi
Publicado 2021

Transcriptomic characterization of cancer-testis antigens identifies MAGEA3 as a driver of tumor progression in hepatocellular carcinoma

por Craig, Amanda J., Garcia-Lezana, Teresa, Ruiz de Galarreta, Marina, Villacorta-Martin, Carlos, Kozlova, Edgar G., Martins-Filho, Sebastiao N., von Felden, Johann, Ahsen, Mehmet Eren, Bresnahan, Erin, Hernandez-Meza, Gabriela, Labgaa, Ismail, D’Avola, Delia, Schwartz, Myron, Llovet, Josep M., Sia, Daniela, Thung, Swan, Losic, Bojan, Lujambio, Amaia, Villanueva, Augusto
Publicado 2021

Effect of ramucirumab on ALBI grade in patients with advanced HCC: Results from REACH and REACH-2

por Kudo, Masatoshi, Galle, Peter R., Brandi, Giovanni, Kang, Yoon-Koo, Yen, Chia-Jui, Finn, Richard S., Llovet, Josep M., Assenat, Eric, Merle, Philippe, Chan, Stephen L., Palmer, Daniel H., Ikeda, Masafumi, Yamashita, Tatsuya, Vogel, Arndt, Huang, Yi-Hsiang, Abada, Paolo B., Yoshikawa, Reigetsu, Shinozaki, Kenta, Wang, Chunxiao, Widau, Ryan C., Zhu, Andrew X.
Publicado 2020

Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma

por Gallon, John, Coto‐Llerena, Mairene, Ercan, Caner, Bianco, Gaia, Paradiso, Viola, Nuciforo, Sandro, Taha‐Melitz, Stephanie, Meier, Marie‐Anne, Boldanova, Tujana, Pérez‐del‐Pulgar, Sofía, Rodríguez‐Tajes, Sergio, von Flüe, Markus, Soysal, Savas D., Kollmar, Otto, Llovet, Josep M., Villanueva, Augusto, Terracciano, Luigi M., Heim, Markus H., Ng, Charlotte K. Y., Piscuoglio, Salvatore
Publicado 2021

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

por Schulze, Kornelius, Imbeaud, Sandrine, Letouzé, Eric, Alexandrov, Ludmil B, Calderaro, Julien, Rebouissou, Sandra, Couchy, Gabrielle, Meiller, Clément, Shinde, Jayendra, Soysouvanh, Frederic, Calatayud, Anna-Line, Pinyol, Roser, Pelletier, Laura, Balabaud, Charles, Laurent, Alexis, Blanc, Jean-Frederic, Mazzaferro, Vincenzo, Calvo, Fabien, Villanueva, Augusto, Nault, Jean-Charles, Bioulac-Sage, Paulette, Stratton, Michael R, Llovet, Josep M, Zucman-Rossi, Jessica
Publicado 2015

Lin28 Enhances Tumorigenesis and is Associated With Advanced Human Malignancies

por Viswanathan, Srinivas R., Powers, John T., Einhorn, William, Hoshida, Yujin, Ng, Tony, Toffanin, Sara, O'Sullivan, Maureen, Lu, Jun, Philips, Letha A., Lockhart, Victoria L., Shah, Samar P., Tanwar, Pradeep S., Mermel, Craig H., Beroukhim, Rameen, Azam, Mohammad, Teixeira, Jose, Meyerson, Matthew, Hughes, Timothy P., Llovet, Josep M, Radich, Jerald, Mullighan, Charles G., Golub, Todd R., Sorensen, Poul H., Daley, George Q.
Publicado 2009