Factors that influence psychiatric trainees’ choice of higher training specialty: mixed-methods study

por Wolstenholme, Nicholas, McKinnon, Iain, Lloyd, Adrian J.
Publicado 2023

Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase

por Alderwick, Luke J, Lloyd, Georgina S, Lloyd, Adrian J, Lovering, Andrew L, Eggeling, Lothar, Besra, Gurdyal S
Publicado 2011

Plant peptidoglycan precursor biosynthesis: Conservation between moss chloroplasts and Gram-negative bacteria

por Dowson, Amanda J, Lloyd, Adrian J, Cuming, Andrew C, Roper, David I, Frigerio, Lorenzo, Dowson, Christopher G
Publicado 2022

The role of the jaw subdomain of peptidoglycan glycosyltransferases for lipid II polymerization

por Punekar, Avinash S., Samsudin, Firdaus, Lloyd, Adrian J., Dowson, Christopher G., Scott, David J., Khalid, Syma, Roper, David I.
Publicado 2018

A conserved zinc-binding site in Acinetobacter baumannii PBP2 required for elongasome-directed bacterial cell shape

por Micelli, Carmina, Dai, Yunfei, Raustad, Nicole, Isberg, Ralph R., Dowson, Christopher G., Lloyd, Adrian J., Geisinger, Edward, Crow, Allister, Roper, David I.
Publicado 2023

Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase

por Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A., Besra, Gurdyal S.
Publicado 2016

A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae

por Aggarwal, Surya D., Lloyd, Adrian J., Yerneni, Saigopalakrishna S., Narciso, Ana Rita, Shepherd, Jennifer, Roper, David I., Dowson, Christopher G., Filipe, Sergio R., Hiller, N. Luisa
Publicado 2021

Structure-based modeling and dynamics of MurM, a Streptococcus pneumoniae penicillin resistance determinant present at the cytoplasmic membrane

por York, Anna, Lloyd, Adrian.J., del Genio, Charo I., Shearer, Jonathan, Hinxman, Karen.J., Fritz, Konstantin, Fulop, Vilmos, Dowson, Christopher.G., Khalid, Syma, Roper, David.I.
Publicado 2021

Specificity Determinants for Lysine Incorporation in Staphylococcus aureus Peptidoglycan as Revealed by the Structure of a MurE Enzyme Ternary Complex

por Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa, Roper, David I.
Publicado 2013

Structural studies suggest aggregation as one of the modes of action for teixobactin

por Öster, Carl, Walkowiak, Grzegorz P., Hughes, Dallas E., Spoering, Amy L., Peoples, Aaron J., Catherwood, Anita C., Tod, Julie A., Lloyd, Adrian J., Herrmann, Torsten, Lewis, Kim, Dowson, Christopher G., Lewandowski, Józef R.
Publicado 2018

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

por Batson, Sarah, de Chiara, Cesira, Majce, Vita, Lloyd, Adrian J., Gobec, Stanislav, Rea, Dean, Fülöp, Vilmos, Thoroughgood, Christopher W., Simmons, Katie J., Dowson, Christopher G., Fishwick, Colin W. G., de Carvalho, Luiz Pedro S., Roper, David I.
Publicado 2017

Biochemical and Structural Characterization of Mycobacterial Aspartyl-tRNA Synthetase AspS, a Promising TB Drug Target

por Gurcha, Sudagar S., Usha, Veeraraghavan, Cox, Jonathan A. G., Fütterer, Klaus, Abrahams, Katherine A., Bhatt, Apoorva, Alderwick, Luke J., Reynolds, Robert C., Loman, Nicholas J., Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J., Ballell, Lluis, Hobrath, Judith V., Besra, Gurdyal S.
Publicado 2014

Study protocol for the randomised controlled trial: Antiglucocorticoid augmentation of anti-Depressants in Depression (The ADD Study)

por McAllister-Williams, R Hamish, Smith, Eleanor, Anderson, Ian M, Barnes, Jane, Gallagher, Peter, Grunze, Heinz CR, Haddad, Peter M, House, Allan O, Hughes, Tom, Lloyd, Adrian J, McColl, Elaine MM, Pearce, Simon HS, Siddiqi, Najma, Sinha, Baxi, Speed, Chris, Steen, I Nick, Wainright, June, Watson, Stuart, Winter, Fiona H, Ferrier, I Nicol
Publicado 2013

Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity

por Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Le Thanh, Giang, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X., Butler, Mark S., Bajaj, Megha, Seifert, Joachim, Singh, Latika, Galley, Nicola F., Roper, David I., Lloyd, Adrian J., Dowson, Christopher G., Cheng, Ting-Jen, Cheng, Wei-Chieh, Demon, Dieter, Meyer, Evelyne, Meutermans, Wim, Cooper, Matthew A.
Publicado 2015