Beyond the Antigen Receptor: Editing the Genome of T-Cells for Cancer Adoptive Cellular Therapies

por Lloyd, Angharad, Vickery, Owen N., Laugel, Bruno
Publicado 2013

A Molecular Switch Abrogates Glycoprotein 100 (gp100) T-cell Receptor (TCR) Targeting of a Human Melanoma Antigen

por Bianchi, Valentina, Bulek, Anna, Fuller, Anna, Lloyd, Angharad, Attaf, Meriem, Rizkallah, Pierre J., Dolton, Garry, Sewell, Andrew K., Cole, David K.
Publicado 2016

T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4

por Coles, Charlotte H., McMurran, Catriona, Lloyd, Angharad, Hock, Miriam, Hibbert, Linda, Raman, Marine C. C., Hayes, Conor, Lupardus, Patrick, Cole, David K., Harper, Stephen
Publicado 2020

T-cell libraries allow simple parallel generation of multiple peptide-specific human T-cell clones

por Theaker, Sarah M., Rius, Cristina, Greenshields-Watson, Alexander, Lloyd, Angharad, Trimby, Andrew, Fuller, Anna, Miles, John J., Cole, David K., Peakman, Mark, Sewell, Andrew K., Dolton, Garry
Publicado 2016

Engineering of Isogenic Cells Deficient for MR1 with a CRISPR/Cas9 Lentiviral System: Tools To Study Microbial Antigen Processing and Presentation to Human MR1-Restricted T Cells

por Laugel, Bruno, Lloyd, Angharad, Meermeier, Erin W., Crowther, Michael D., Connor, Thomas R., Dolton, Garry, Miles, John J., Burrows, Scott R., Gold, Marielle C., Lewinsohn, David M., Sewell, Andrew K.
Publicado 2016

Peptide Super-Agonist Enhances T-Cell Responses to Melanoma

por Galloway, Sarah A. E., Dolton, Garry, Attaf, Meriem, Wall, Aaron, Fuller, Anna, Rius, Cristina, Bianchi, Valentina, Theaker, Sarah, Lloyd, Angharad, Caillaud, Marine E., Svane, Inge Marie, Donia, Marco, Cole, David K., Szomolay, Barbara, Rizkallah, Pierre, Sewell, Andrew K.
Publicado 2019

Structural Mechanism Underpinning Cross-reactivity of a CD8(+) T-cell Clone That Recognizes a Peptide Derived from Human Telomerase Reverse Transcriptase

por Cole, David K., van den Berg, Hugo A., Lloyd, Angharad, Crowther, Michael D., Beck, Konrad, Ekeruche-Makinde, Julia, Miles, John J., Bulek, Anna M., Dolton, Garry, Schauenburg, Andrea J., Wall, Aaron, Fuller, Anna, Clement, Mathew, Laugel, Bruno, Rizkallah, Pierre J., Wooldridge, Linda, Sewell, Andrew K.
Publicado 2017

Genome-wide CRISPR-Cas9 Screening Reveals Ubiquitous T cell Cancer Targeting via the monomorphic MHC class I related protein MR1

por Crowther, Michael D., Dolton, Garry, Legut, Mateusz, Caillaud, Marine E., Lloyd, Angharad, Attaf, Meriem, Galloway, Sarah A. E., Rius, Cristina, Farrell, Colin P., Szomolay, Barbara, Ager, Ann, Parker, Alan L., Fuller, Anna, Donia, Marco, McCluskey, James, Rossjohn, Jamie, Svane, Inge Marie, Phillips, John, Sewell, Andrew K.
Publicado 2020

CD4(+) T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features

por Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L., Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J., Gallimore, Awen M., Sewell, Andrew K., Godkin, Andrew J., Cole, David K.
Publicado 2020