Loss-of-Function Mutation in Myostatin Reduces Tumor Necrosis Factor α Production and Protects Liver Against Obesity-Induced Insulin Resistance

por Wilkes, Jason J., Lloyd, David J., Gekakis, Nick
Publicado 2009

A Point Mutation in Sec61α1 Leads to Diabetes and Hepatosteatosis in Mice

por Lloyd, David J., Wheeler, Matthew C., Gekakis, Nicholas
Publicado 2010

Diabetes Insipidus in Mice with a Mutation in Aquaporin-2

por Lloyd, David J, Hall, Frank Wesley, Tarantino, Lisa M, Gekakis, Nicholas
Publicado 2005

The Effect of the G (1) - S transition Checkpoint on an Age Structured Cell Cycle Model

por Chaffey, Gary S., Lloyd, David J. B., Skeldon, Anne C., Kirkby, Norman F.
Publicado 2014

Modelling and Detecting Tumour Oxygenation Levels

por Skeldon, Anne C., Chaffey, Gary, Lloyd, David J. B., Mohan, Vineet, Bradley, David A., Nisbet, Andrew
Publicado 2012

A Gain-of-Function Mutation in Adenylate Cyclase 3 Protects Mice from Diet-Induced Obesity

por Pitman, Jeffrey L., Wheeler, Matthew C., Lloyd, David J., Walker, John R., Glynne, Richard J., Gekakis, Nicholas
Publicado 2014

FGF21 Promotes Metabolic Homeostasis via White Adipose and Leptin in Mice

por Véniant, Murielle M., Hale, Clarence, Helmering, Joan, Chen, Michelle M., Stanislaus, Shanaka, Busby, Jim, Vonderfecht, Steven, Xu, Jing, Lloyd, David J.
Publicado 2012

Participatory Development and Analysis of a Fuzzy Cognitive Map of the Establishment of a Bio-Based Economy in the Humber Region

por Penn, Alexandra S., Knight, Christopher J. K., Lloyd, David J. B., Avitabile, Daniele, Kok, Kasper, Schiller, Frank, Woodward, Amy, Druckman, Angela, Basson, Lauren
Publicado 2013

A Volumetric Method for Quantifying Atherosclerosis in Mice by Using MicroCT: Comparison to En Face

por Lloyd, David J., Helmering, Joan, Kaufman, Stephen A., Turk, James, Silva, Matt, Vasquez, Sergio, Weinstein, David, Johnston, Brad, Hale, Clarence, Véniant, Murielle M.
Publicado 2011

Pancreatic islet expression profiling in diabetes-prone C57BLKS/J mice reveals transcriptional differences contributed by DBA loci, including Plagl1 and Nnt

por Anderson, Abraham A, Helmering, Joan, Juan, Todd, Li, Chi-Ming, McCormick, Jocelyn, Graham, Melissa, Baker, Daniel M, Damore, Michael A, Véniant, Murielle M, Lloyd, David J
Publicado 2009

Chronic glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism desensitizes adipocyte GIPR activity mimicking functional GIPR antagonism

por Killion, Elizabeth A., Chen, Michelle, Falsey, James R., Sivits, Glenn, Hager, Todd, Atangan, Larissa, Helmering, Joan, Lee, Jae, Li, Hongyan, Wu, Bin, Cheng, Yuan, Véniant, Murielle M., Lloyd, David J.
Publicado 2020

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

por Xu, Jing, Lloyd, David J., Hale, Clarence, Stanislaus, Shanaka, Chen, Michelle, Sivits, Glenn, Vonderfecht, Steven, Hecht, Randy, Li, Yue-Sheng, Lindberg, Richard A., Chen, Jin-Long, Jung, Dae Young, Zhang, Zhiyou, Ko, Hwi Jin, Kim, Jason K., Véniant, Murielle M.
Publicado 2009

A mutation in Ampd2 is associated with nephrotic syndrome and hypercholesterolemia in mice

por Helmering, Joan, Juan, Todd, Li, Chi Ming, Chhoa, Mark, Baron, Will, Gyuris, Tibor, Richards, William G, Turk, James R, Lawrence, Jeff, Cosgrove, Patrick A, Busby, Jim, Kim, Ki Won, Kaufman, Stephen A, Cummings, Connie, Carlson, George, Véniant, Murielle M, Lloyd, David J
Publicado 2014

GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

por Lu, Shu-Chen, Chen, Michelle, Atangan, Larissa, Killion, Elizabeth A., Komorowski, Renee, Cheng, Yuan, Netirojjanakul, Chawita, Falsey, James R., Stolina, Marina, Dwyer, Denise, Hale, Clarence, Stanislaus, Shanaka, Hager, Todd, Thomas, Veena A., Harrold, John M., Lloyd, David J., Véniant, Murielle M.
Publicado 2021

Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor

por Min, Xiaoshan, Yie, Junming, Wang, Jinghong, Chung, Ben C., Huang, Ching-Shin, Xu, Haoda, Yang, Jie, Deng, Liying, Lin, Joanne, Chen, Qing, Abbott, Christina M., Gundel, Caroline, Thibault, Stephen A., Meng, Tina, Bates, Darren L., Lloyd, David J., Véniant, Murielle M., Wang, Zhulun
Publicado 2020