Carbinolamine Formation and Dehydration in a DNA Repair Enzyme Active Site

por Dodson, M. L., Walker, Ross C., Lloyd, R. Stephen
Publicado 2012

Evidence for the Involvement of DNA Repair Enzyme NEIL1 in Nucleotide Excision Repair of (5′R)- and (5′S)-8,5′-Cyclo-2′-deoxyadenosines

por Jaruga, Pawel, Xiao, Yan, Vartanian, Vladimir, Lloyd, R. Stephen, Dizdaroglu, Miral
Publicado 2010

DNA Polymerase β Gap-Filling Translesion DNA Synthesis

por Chary, Parvathi, Beard, William A., Wilson, Samuel H., Lloyd, R. Stephen
Publicado 2012

Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts

por Chary, Parvathi, Beard, William A., Wilson, Samuel H., Lloyd, R. Stephen
Publicado 2013

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction

por Sampath, Harini, Vartanian, Vladimir, Rollins, M. Rick, Sakumi, Kunihiko, Nakabeppu, Yusaku, Lloyd, R. Stephen
Publicado 2012

The Stereochemistry of trans-4-Hydroxynonenal-Derived Exocyclic 1,N(2)-2′-Deoxyguanosine Adducts Modulates Formation of Interstrand Cross-Links in the 5′-CpG-3′ Sequence

por Huang, Hai, Wang, Hao, Qi, Nan, Lloyd, R. Stephen, Rizzo, Carmelo J., Stone, Michael P.
Publicado 2008

8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

por Vartanian, Vladimir, Tumova, Jana, Dobrzyn, Pawel, Dobrzyn, Agnieszka, Nakabeppu, Yusaku, Lloyd, R. Stephen, Sampath, Harini
Publicado 2017

OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model

por Simon, Holly, Vartanian, Vladimir, Wong, Melissa H., Nakabeppu, Yusaku, Sharma, Priyanka, Lloyd, R. Stephen, Sampath, Harini
Publicado 2020

Chemistry and Biology of DNA Containing 1,N(2)-Deoxyguanosine Adducts of the α,β-Unsaturated Aldehydes Acrolein, Crotonaldehyde, and 4-Hydroxynonenal

por Minko, Irina G., Kozekov, Ivan D., Harris, Thomas M., Rizzo, Carmelo J., Lloyd, R. Stephen, Stone, Michael P.
Publicado 2009

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ

por Yamanaka, Kinrin, Dorjsuren, Dorjbal, Eoff, Robert L., Egli, Martin, Maloney, David J., Jadhav, Ajit, Simeonov, Anton, Lloyd, R. Stephen
Publicado 2012

Maternal Transmission of Human OGG1 Protects Mice Against Genetically- and Diet-Induced Obesity Through Increased Tissue Mitochondrial Content

por Burchat, Natalie, Sharma, Priyanka, Ye, Hong, Komakula, Sai Santosh Babu, Dobrzyn, Agnieszka, Vartanian, Vladimir, Lloyd, R. Stephen, Sampath, Harini
Publicado 2021

Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-γ-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage,

por Huang, Hai, Kozekov, Ivan D., Kozekova, Albena, Rizzo, Carmelo J., McCullough, Amanda K., Lloyd, R. Stephen, Stone, Michael P.
Publicado 2010

The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue

por Komakula, Sai Santosh Babu, Tumova, Jana, Kumaraswamy, Deeptha, Burchat, Natalie, Vartanian, Vladimir, Ye, Hong, Dobrzyn, Agnieszka, Lloyd, R. Stephen, Sampath, Harini
Publicado 2018

Novel Enzymatic Function of DNA Polymerase ν in Translesion DNA Synthesis Past Major Groove DNA−Peptide and DNA−DNA Cross-Links

por Yamanaka, Kinrin, Minko, Irina G., Takata, Kei-ichi, Kolbanovskiy, Alexander, Kozekov, Ivan D., Wood, Richard D., Rizzo, Carmelo J., Lloyd, R. Stephen
Publicado 2010

γ-Hydroxy-1,N(2)-propano-2′-deoxyguanosine DNA Adduct Conjugates the N-Terminal Amine of the KWKK Peptide via a Carbinolamine Linkage

por Huang, Hai, Wang, Hao, Voehler, Markus W., Kozekova, Albena, Rizzo, Carmelo J., McCullough, Amanda K., Lloyd, R. Stephen, Stone, Michael P.
Publicado 2011

The Base Excision Repair Pathway Is Required for Efficient Lentivirus Integration

por Yoder, Kristine E., Espeseth, Amy, Wang, Xiao-hong, Fang, Qingming, Russo, Maria Teresa, Lloyd, R. Stephen, Hazuda, Daria, Sobol, Robert W., Fishel, Richard
Publicado 2011

Synthesis and Characterization of (15)N(5)-Labeled Aflatoxin B(1)–Formamidopyrimidines and Aflatoxin B(1)–N7-Guanine from a Partial Double-Stranded Oligodeoxynucleotide as Internal...

por Jaruga, Pawel, Tomar, Rachana, Kant, Melis, Vartanian, Vladimir, Sexton, Benjamin, Rizzo, Carmelo J., Turesky, Robert J., Stone, Michael P., Lloyd, R. Stephen, Dizdaroglu, Miral
Publicado 2023

Ring-Opening of the γ-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4

por Shanmugam, Ganesh, Minko, Irina G., Banerjee, Surajit, Christov, Plamen P., Kozekov, Ivan D., Rizzo, Carmelo J., Lloyd, R. Stephen, Egli, Martin, Stone, Michael P.
Publicado 2013

Base excision repair of the N-(2-deoxy-d-erythro-pentofuranosyl)-urea lesion by the hNEIL1 glycosylase

por Tomar, Rachana, Minko, Irina G, Sharma, Pankaj, Kellum, Andrew H, Lei, Li, Harp, Joel M, Iverson, T M, Lloyd, R Stephen, Egli, Martin, Stone, Michael P
Publicado 2023

Inhibition of DNA Glycosylases via Small Molecule Purine Analogs

por Jacobs, Aaron C., Calkins, Marcus J., Jadhav, Ajit, Dorjsuren, Dorjbal, Maloney, David, Simeonov, Anton, Jaruga, Pawel, Dizdaroglu, Miral, McCullough, Amanda K., Lloyd, R. Stephen
Publicado 2013