Long Non-coding RNAs: Major Regulators of Cell Stress in Cancer

por Connerty, Patrick, Lock, Richard B., de Bock, Charles E.
Publicado 2020

Reversal of glucocorticoid resistance in paediatric acute lymphoblastic leukaemia is dependent on restoring BIM expression

por Toscan, Cara E., Jing, Duohui, Mayoh, Chelsea, Lock, Richard B.
Publicado 2020

Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells

por Mesbahi, Yashar, Trahair, Toby N., Lock, Richard B., Connerty, Patrick
Publicado 2022

Circulating Tumor DNA in Pediatric Cancer

por Doculara, Louise, Trahair, Toby N., Bayat, Narges, Lock, Richard B.
Publicado 2022

Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia

por Bhadri, Vivek A, Cowley, Mark J, Kaplan, Warren, Trahair, Toby N, Lock, Richard B
Publicado 2011

The Promise of Single-cell Technology in Providing New Insights Into the Molecular Heterogeneity and Management of Acute Lymphoblastic Leukemia

por Pearson, Holly C.L., Hunt, Kooper V., Trahair, Toby N., Lock, Richard B., Lee, Heather J., de Bock, Charles E.
Publicado 2022

Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia

por Wallington-Beddoe, Craig T., Don, Anthony S., Hewson, John, Qiao, Qiao, Papa, Rachael A., Lock, Richard B., Bradstock, Kenneth F., Bendall, Linda J.
Publicado 2012

Correction: Disparate In Vivo Efficacy of FTY720 in Xenograft Models of Philadelphia Positive and Negative B-lineage Acute Lymphoblastic Leukemia

por Wallington-Beddoe, Craig T., Don, Anthony S., Hewson, John, Qiao, Qiao, Papa, Rachael A., Lock, Richard B., Bradstock, Kenneth F., Bendall, Linda J.
Publicado 2012

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mecha...

por Wong, Nicholas C, Bhadri, Vivek A, Maksimovic, Jovana, Parkinson-Bates, Mandy, Ng, Jane, Craig, Jeff M, Saffery, Richard, Lock, Richard B
Publicado 2014

Examining treatment responses of diagnostic marrow in murine xenografts to predict relapse in children with acute lymphoblastic leukaemia

por Alruwetei, Abdulmohsen M., Bendak, Katerina, Yadav, Babasaheb D., Carol, Hernan, Evans, Kathryn, Mayoh, Chelsea, Sutton, Rosemary, Marshall, Glenn M., Lock, Richard B.
Publicado 2020

Development of siRNA-Loaded Lipid Nanoparticles Targeting Long Non-Coding RNA LINC01257 as a Novel and Safe Therapeutic Approach for t(8;21) Pediatric Acute Myeloid Leukemia

por Connerty, Patrick, Moles, Ernest, de Bock, Charles E., Jayatilleke, Nisitha, Smith, Jenny L., Meshinchi, Soheil, Mayoh, Chelsea, Kavallaris, Maria, Lock, Richard B.
Publicado 2021

Validation of a mouse xenograft model system for gene expression analysis of human acute lymphoblastic leukaemia

por Samuels, Amy L, Peeva, Violet K, Papa, Rachael A, Firth, Marin J, Francis, Richard W, Beesley, Alex H, Lock, Richard B, Kees, Ursula R
Publicado 2010

Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression

por McClure, Barbara J., Heatley, Susan L., Kok, Chung H, Sadras, Teresa, An, Jiyuan, Hughes, Timothy P., Lock, Richard B., Yeung, David, Sutton, Rosemary, White, Deborah L
Publicado 2018

Pharmacokinetic Modeling of an Induction Regimen for In Vivo Combined Testing of Novel Drugs against Pediatric Acute Lymphoblastic Leukemia Xenografts

por Szymanska, Barbara, Wilczynska-Kalak, Urszula, Kang, Min H., Liem, Natalia L. M., Carol, Hernan, Boehm, Ingrid, Groepper, Daniel, Reynolds, C. Patrick, Stewart, Clinton F., Lock, Richard B.
Publicado 2012

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1

por Shahbazi, Jeyran, Scarlett, Christopher J., Norris, Murray D., Liu, Bing, Haber, Michelle, Tee, Andrew E., Carrier, Alice, Biankin, Andrew V., London, Wendy B., Marshall, Glenn M., Lock, Richard B., Liu, Tao
Publicado 2014

A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts

por El-Hoss, Jad, Jing, Duohui, Evans, Kathryn, Toscan, Cara, Xie, Jinhan, Lee, Hyunjoo, Taylor, Renea A., Lawrence, Mitchell G., Risbridger, Gail P., MacKenzie, Karen L., Sutton, Rosemary, Lock, Richard B.
Publicado 2016

Protocol for the avatar acceptability study: a multiperspective cross-sectional study evaluating the acceptability of using patient-derived xenografts to guide personalised cancer...

por Wakefield, Claire E, Doolan, Emma L, Fardell, Joanna E, Signorelli, Christina, Quinn, Veronica F, Tucker, Kathy F, Patenaude, Andrea F, Marshall, Glenn M, Lock, Richard B, Georgiou, Gabrielle, Cohn, Richard J
Publicado 2018

Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells

por Bayat, Narges, McOrist, Nathan, Ariotti, Nicholas, Lai, May, Sia, Keith CS, Li, Yuhuan, Grace, James L, Quinn, John F, Whittaker, Michael R, Kavallaris, Maria, Davis, Thomas P, Lock, Richard B
Publicado 2019

PLK1 as a cooperating partner for BCL2-mediated antiapoptotic program in leukemia

por Shah, Kinjal, Nasimian, Ahmad, Ahmed, Mehreen, Al Ashiri, Lina, Denison, Linn, Sime, Wondossen, Bendak, Katerina, Kolosenko, Iryna, Siino, Valentina, Levander, Fredrik, Palm-Apergi, Caroline, Massoumi, Ramin, Lock, Richard B., Kazi, Julhash U.
Publicado 2023

Heterogeneity in mechanisms of emergent resistance in pediatric T-cell acute lymphoblastic leukemia

por Yadav, Babasaheb D., Samuels, Amy L., Wells, Julia E., Sutton, Rosemary, Venn, Nicola C., Bendak, Katerina, Anderson, Denise, Marshall, Glenn M., Cole, Catherine H., Beesley, Alex H., Kees, Ursula R., Lock, Richard B.
Publicado 2016