Inhibition of VEGF and Angiopoietin-2 to Reduce Brain Metastases of Breast Cancer Burden

por Bohn, Kaci A., Adkins, Chris E., Nounou, Mohamed I., Lockman, Paul R.
Publicado 2017

Permeability across a novel microfluidic blood-tumor barrier model

por Terrell-Hall, Tori B., Ammer, Amanda G., Griffith, Jessica I. G., Lockman, Paul R.
Publicado 2017

Trastuzumab distribution in an in-vivo and in-vitro model of brain metastases of breast cancer

por Terrell-Hall, Tori B., Nounou, Mohamed Ismail, El-Amrawy, Fatema, Griffith, Jessica I.G., Lockman, Paul R.
Publicado 2017

Conditional knockout of SHP2 in ErbB2 transgenic mice or inhibition in HER2-amplified breast cancer cell lines blocks oncogene expression and tumorigenesis

por Zhao, Hua, Martin, Elisha, Matalkah, Fatimah, Shah, Neal, Ivanov, Alexey, Ruppert, J. Michael, Lockman, Paul R., Agazie, Yehenew M.
Publicado 2018

Long non-coding RNA FAM83H-AS1 is regulated by human papillomavirus 16 E6 independently of p53 in cervical cancer cells

por Barr, Jamie A., Hayes, Karen E., Brownmiller, Tayvia, Harold, Abby D., Jagannathan, Rajaganapathi, Lockman, Paul R., Khan, Saleem, Martinez, Ivan
Publicado 2019

Permeability changes and effect of chemotherapy in brain adjacent to tumor in an experimental model of metastatic brain tumor from breast cancer

por Mohammad, Afroz S., Adkins, Chris E., Shah, Neal, Aljammal, Rawaa, Griffith, Jessica I. G., Tallman, Rachel M., Jarrell, Katherine L., Lockman, Paul R.
Publicado 2018

Nanoparticles as a Tool in Neuro-Oncology Theranostics

por Klein, Andrea L., Nugent, Grant, Cavendish, John, Geldenhuys, Werner J., Sriram, Krishnan, Porter, Dale, Fladeland, Ross, Lockman, Paul R., Sherman, Jonathan H.
Publicado 2021

A Review of Mathematics Determining Solute Uptake at the Blood–Brain Barrier in Normal and Pathological Conditions

por Sprowls, Samuel A., Saralkar, Pushkar, Arsiwala, Tasneem, Adkins, Christopher E., Blethen, Kathryn E., Pizzuti, Vincenzo J., Shah, Neal, Fladeland, Ross, Lockman, Paul R.
Publicado 2021

NKTR-102 Efficacy versus irinotecan in a mouse model of brain metastases of breast cancer

por Adkins, Chris E., Nounou, Mohamed I., Hye, Tanvirul, Mohammad, Afroz S., Terrell-Hall, Tori, Mohan, Neel K., Eldon, Michael A., Hoch, Ute, Lockman, Paul R.
Publicado 2015

A mouse Model of Focal Vascular Injury Induces Astrocyte Reactivity, Tau Oligomers, and Aberrant Behavior

por Logsdon, Aric F., Lucke-Wold, Brandon P., Turner, Ryan C., Li, Xinlan, Adkins, Chris E., Mohammad, Afroz S., Huber, Jason D., Rosen, Charles L., Lockman, Paul R.
Publicado 2017

Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment

por Nwafor, Divine C, Brichacek, Allison L, Mohammad, Afroz S, Griffith, Jessica, Lucke-Wold, Brandon P, Benkovic, Stanley A, Geldenhuys, Werner J, Lockman, Paul R, Brown, Candice M
Publicado 2019

Drug resistance occurred in a newly characterized preclinical model of lung cancer brain metastasis

por Shah, Neal, Liu, Zhongwei, Tallman, Rachel M., Mohammad, Afroz, Sprowls, Samuel A., Saralkar, Pushkar A., Vickers, Schuyler D., Pinti, Mark V., Gao, Weimin, Lockman, Paul R.
Publicado 2020

Circadian Influences on Chemotherapy Efficacy in a Mouse Model of Brain Metastases of Breast Cancer

por Walker, William H., Sprowls, Samuel A., Bumgarner, Jacob R., Liu, Jennifer A., Meléndez-Fernández, O. Hecmarie, Walton, James C., Lockman, Paul R., DeVries, A. Courtney, Nelson, Randy J.
Publicado 2021

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

por Adkins, Chris E., Mittapalli, Rajendar K., Manda, Vamshi K., Nounou, Mohamed I., Mohammad, Afroz S., Terrell, Tori B., Bohn, Kaci A., Yasemin, Celik, Grothe, Tiffany R., Lockman, Julie A., Lockman, Paul R.
Publicado 2013

MiR-34a Interacts with Cytochrome c and Shapes Stroke Outcomes

por Hu, Heng, Hone, Emily A., Provencher, Edward A. P., Sprowls, Samuel A., Farooqi, Imran, Corbin, Deborah R., Sarkar, Saumyendra N., Hollander, John M., Lockman, Paul R., Simpkins, James W., Ren, Xuefang
Publicado 2020

Characterization of passive permeability after low intensity focused ultrasound mediated blood–brain barrier disruption in a preclinical model

por Arsiwala, Tasneem A., Sprowls, Samuel A., Blethen, Kathryn E., Fladeland, Ross A., Wolford, Cullen P., Kielkowski, Brooke N., Glass, Morgan J., Wang, Peng, Wilson, Olivia, Carpenter, Jeffrey S., Ranjan, Manish, Finomore, Victor, Rezai, Ali, Lockman, Paul R.
Publicado 2022

Blood-tumor barrier opening by MRI-guided transcranial focused ultrasound in a preclinical breast cancer brain metastasis model improves efficacy of combinatorial chemotherapy

por Arsiwala, Tasneem A., Blethen, Kathryn E., Wolford, Cullen P., Panchal, Dhruvi M., Sprowls, Samuel A., Fladeland, Ross A., Kielkowski, Brooke N., Pritt, Trenton A., Wang, Peng, Wilson, Olivia, Carpenter, Jeffrey S., Finomore, Victor, Rezai, Ali, Lockman, Paul R.
Publicado 2023

Modulation of the blood-tumor barrier to enhance drug delivery and efficacy for brain metastases

por Blethen, Kathryn E, Arsiwala, Tasneem A, Fladeland, Ross A, Sprowls, Samuel A, Panchal, Dhruvi M, Adkins, Chris E, Kielkowski, Brooke N, Earp, Leland E, Glass, Morgan J, Pritt, Trenton A, Cabuyao, Yssabela M, Aulakh, Sonikpreet, Lockman, Paul R
Publicado 2021

Development of a Cx46 Targeting Strategy for Cancer Stem Cells

por Mulkearns-Hubert, Erin E., Torre-Healy, Luke A., Silver, Daniel J., Eurich, Jennifer T., Bayik, Defne, Serbinowski, Emily, Hitomi, Masahiro, Zhou, John, Przychodzen, Bartlomiej, Zhang, Renliang, Sprowls, Samuel A., Hale, James S., Alban, Tyler J., Berezovsky, Artem, Bell, Brent A., Lockman, Paul R., Jha, Babal K., Lathia, Justin D.
Publicado 2019