Computational Methods for the Analysis of Array Comparative Genomic Hybridization

por Chari, Raj, Lockwood, William W., Lam, Wan L.
Publicado 2007

New insights into the biology and development of lung cancer in never smokers—implications for early detection and treatment

por Wang, Peiyao, Sun, Sophie, Lam, Stephen, Lockwood, William W.
Publicado 2023

Resistance to BET inhibitors in lung adenocarcinoma is mediated by casein kinase phosphorylation of BRD4

por Calder, Jack, Nagelberg, Amy, Luu, Jennifer, Lu, Daniel, Lockwood, William W.
Publicado 2021

Emerging Molecular Dependencies of Mutant EGFR-Driven Non-Small Cell Lung Cancer

por Farnsworth, Dylan A., Chen, Yankuan T., de Rappard Yuswack, Georgia, Lockwood, William W.
Publicado 2021

Synthetic lethality in lung cancer and translation to clinical therapies

por Leung, Ada W. Y., de Silva, Tanya, Bally, Marcel B., Lockwood, William W.
Publicado 2016

Tandem mass tag-based thermal proteome profiling for the discovery of drug-protein interactions in cancer cells

por Johnson, Fraser D., Hughes, Christopher S., Liu, Alvin, Lockwood, William W., Morin, Gregg B.
Publicado 2023

An integrative multi-dimensional genetic and epigenetic strategy to identify aberrant genes and pathways in cancer

por Chari, Raj, Coe, Bradley P, Vucic, Emily A, Lockwood, William W, Lam, Wan L
Publicado 2010

Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma

por Unni, Arun M, Lockwood, William W, Zejnullahu, Kreshnik, Lee-Lin, Shih-Queen, Varmus, Harold
Publicado 2015

The Novel Ubiquitin Ligase Complex, SCF(Fbxw4), Interacts with the COP9 Signalosome in an F-Box Dependent Manner, Is Mutated, Lost and Under-Expressed in Human Cancers

por Lockwood, William W., Chandel, Sahiba K., Stewart, Greg L., Erdjument-Bromage, Hediye, Beverly, Levi J.
Publicado 2013

MET Exon 14 Splice-Site Mutations Preferentially Activate KRAS Signaling to Drive Tumourigenesis

por Lu, Daniel, Nagelberg, Amy, Chow, Justine LM, Chen, Yankuan T, Michalchuk, Quentin, Somwar, Romel, Lockwood, William W.
Publicado 2022

The PIM family of oncoproteins: Small kinases with huge implications in myeloid leukemogenesis and as therapeutic targets

por Saurabh, Kumar, Scherzer, Michael T., Shah, Parag P., Mims, Alice S., Lockwood, William W., Kraft, Andrew S., Beverly, Levi J.
Publicado 2014

Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells

por Unni, Arun M, Harbourne, Bryant, Oh, Min Hee, Wild, Sophia, Ferrarone, John R, Lockwood, William W, Varmus, Harold
Publicado 2018

Expression of the lncRNA Maternally Expressed Gene 3 (MEG3) Contributes to the Control of Lung Cancer Cell Proliferation by the Rb Pathway

por Kruer, Traci L., Dougherty, Susan M., Reynolds, Lindsey, Long, Elizabeth, de Silva, Tanya, Lockwood, William W., Clem, Brian F.
Publicado 2016

Ubiquilin1 Represses Migration and Epithelial to Mesenchymal Transition of Human Non-small Cell Lung Cancer Cells

por Shah, Parag P., Lockwood, William W., Saurabh, Kumar, Kurlawala, Zimple, Shannon, Sean P., Waigel, Sabine, Zacharias, Wolfgang, Beverly, Levi J.
Publicado 2014

Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer

por Inoue, Yusuke, Nikolic, Ana, Farnsworth, Dylan, Shi, Rocky, Johnson, Fraser D, Liu, Alvin, Ladanyi, Marc, Somwar, Romel, Gallo, Marco, Lockwood, William W
Publicado 2021

SIGMA: A System for Integrative Genomic Microarray Analysis of Cancer Genomes

por Chari, Raj, Lockwood, William W, Coe, Bradley P, Chu, Anna, Macey, Devon, Thomson, Andrew, Davies, Jonathan J, MacAulay, Calum, Lam, Wan L
Publicado 2006

MIR155 Regulation of Ubiquilin1 and Ubiquilin2: Implications in Cellular Protection and Tumorigenesis()()

por Yadav, Sanjay, Singh, Nishant, Shah, Parag P., Rowbotham, David A., Malik, Danial, Srivastav, Ankita, Shankar, Jai, Lam, Wan L., Lockwood, William W., Beverly, Levi J.
Publicado 2017

MicroRNA Modification of Coxsackievirus B3 Decreases Its Toxicity, while Retaining Oncolytic Potency against Lung Cancer

por Liu, Huitao, Xue, Yuan Chao, Deng, Haoyu, Mohamud, Yasir, Ng, Chen Seng, Chu, Axel, Lim, Chinten James, Lockwood, William W., Jia, William W.G., Luo, Honglin
Publicado 2020

MicroRNA Modification of Coxsackievirus B3 Decreases Its Toxicity, while Retaining Oncolytic Potency against Lung Cancer

por Liu, Huitao, Xue, Yuan Chao, Deng, Haoyu, Mohamud, Yasir, Ng, Chen Seng, Chu, Axel, Lim, Chinten James, Lockwood, William W., Jia, William W.G., Luo, Honglin
Publicado 2021

Delineating spatial cell-cell interactions in the solid tumour microenvironment through the lens of highly multiplexed imaging

por Cohn, David E., Forder, Aisling, Marshall, Erin A., Vucic, Emily A., Stewart, Greg L., Noureddine, Kouther, Lockwood, William W., MacAulay, Calum E., Guillaud, Martial, Lam, Wan L.
Publicado 2023