The two faces of DNA oxidation in genomic and functional mosaicism during aging in human neurons

por Lodato, Michael A., Ziegenfuss, Jennifer S.
Publicado 2022

Editorial: Somatic mutations, genome mosaicism and aging

por Lodato, Michael A., Vijg, Jan
Publicado 2023

PaSD-qc: quality control for single cell whole-genome sequencing data using power spectral density estimation

por Sherman, Maxwell A, Barton, Alison R, Lodato, Michael A, Vitzthum, Carl, Coulter, Michael E, Walsh, Christopher A, Park, Peter J
Publicado 2018

SOX2 Co-Occupies Distal Enhancer Elements with Distinct POU Factors in ESCs and NPCs to Specify Cell State

por Lodato, Michael A., Ng, Christopher W., Wamstad, Joseph A., Cheng, Albert W., Thai, Kevin K., Fraenkel, Ernest, Jaenisch, Rudolf, Boyer, Laurie A.
Publicado 2013

Persistent DNA damage associated with ATM kinase deficiency promotes microglial dysfunction

por Bourseguin, Julie, Cheng, Wen, Talbot, Emily, Hardy, Liana, Lai, Jenny, Jeffries, Ailsa M, Lodato, Michael A, Lee, Eunjung Alice, Khoronenkova, Svetlana V
Publicado 2022

Prevalence and mechanisms of somatic deletions in single human neurons during normal aging and in DNA repair disorders

por Kim, Junho, Huang, August Yue, Johnson, Shelby L., Lai, Jenny, Isacco, Laura, Jeffries, Ailsa M., Miller, Michael B., Lodato, Michael A., Walsh, Christopher A., Lee, Eunjung Alice
Publicado 2022

Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity

por Choudhury, Sangita, Huang, August Yue, Kim, Junho, Zhou, Zinan, Morillo, Katherine, Maury, Eduardo A., Tsai, Jessica W., Miller, Michael B., Lodato, Michael A., Araten, Sarah, Hilal, Nazia, Lee, Eunjung Alice, Chen, Ming Hui, Walsh, Christopher A.
Publicado 2022