Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Prediction...

por Loer, Helena Leonie Hanae, Türk, Denise, Gómez-Mantilla, José David, Selzer, Dominik, Lehr, Thorsten
Publicado 2022

Physiologically based pharmacokinetic modeling of tacrolimus for food–drug and CYP3A drug–drug–gene interaction predictions

por Loer, Helena Leonie Hanae, Feick, Denise, Rüdesheim, Simeon, Selzer, Dominik, Schwab, Matthias, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Lehr, Thorsten
Publicado 2023

Physiologically‐based pharmacokinetic modeling of quinidine to establish a CYP3A4, P‐gp, and CYP2D6 drug–drug–gene interaction network

por Feick, Denise, Rüdesheim, Simeon, Marok, Fatima Zahra, Selzer, Dominik, Loer, Helena Leonie Hanae, Teutonico, Donato, Frechen, Sebastian, van der Lee, Maaike, Moes, Dirk Jan A. R., Swen, Jesse J., Schwab, Matthias, Lehr, Thorsten
Publicado 2023