A Comparison of Single Fraction and Multi Fraction Radiosurgery on the Gamma Knife ICON: A Single Institution Review

por Loftus, Joseph P., Shepard, Matthew, Liang, Yun, Yu, Alexander, Karlovits, Stephen M., Wegner, Rodney E.
Publicado 2022

Combinatorial efficacy of entospletinib and chemotherapy in patient-derived xenograft models of infant acute lymphoblastic leukemia

por Loftus, Joseph P., Yahiaoui, Anella, Brown, Patrick A, Niswander, Lisa M., Bagashev, Asen, Wang, Min, Shauf, Allyson, Tannheimer, Stacey, Tasian, Sarah K.
Publicado 2020

Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3-mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leuk...

por Niswander, Lisa M., Graff, Zachary T., Chien, Christopher D., Chukinas, John A., Meadows, Christina A., Leach, Lillie C., Loftus, Joseph P., Kohler, M. Eric, Tasian, Sarah K., Fry, Terry J.
Publicado 2022

Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia

por Ding, Yang-Yang, Kim, Hannah, Madden, Kellyn, Loftus, Joseph P., Chen, Gregory M., Allen, David Hottman, Zhang, Ruitao, Xu, Jason, Chen, Chia-Hui, Hu, Yuxuan, Tasian, Sarah K., Tan, Kai
Publicado 2021

Therapeutic potential of ruxolitinib and ponatinib in patients with EPOR-rearranged Philadelphia chromosome-like acute lymphoblastic leukemia

por Niswander, Lisa M., Loftus, Joseph P, Lainey, Élodie, Caye-Eude, Aurélie, Pondrom, Morgane, Hottman, David A., Iacobucci, Ilaria, Mullighan, Charles G., Jain, Nitin, Konopleva, Marina, Cavé, Hélène, Baruchel, André, Rohrlich, Pierre S., Tasian, Sarah K.
Publicado 2021

Temsirolimus combined with cyclophosphamide and etoposide for pediatric patients with relapsed/refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia...

por Tasian, Sarah K., Silverman, Lewis B., Whitlock, James A., Sposto, Richard, Loftus, Joseph P., Schafer, Eric S., Schultz, Kirk R., Hutchinson, Raymond J., Gaynon, Paul S., Orgel, Etan, Bateman, Caroline M., Cooper, Todd M., Laetsch, Theodore W., Sulis, Maria Luisa, Chi, Yueh-Yun, Malvar, Jemily, Wayne, Alan S., Rheingold, Susan R.
Publicado 2022

Alternative splicing of its 5′-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies

por Ang, Zhiwei, Paruzzo, Luca, Hayer, Katharina E., Schmidt, Carolin, Torres Diz, Manuel, Xu, Feng, Zankharia, Urvi, Zhang, Yunlin, Soldan, Samantha, Zheng, Sisi, Falkenstein, Catherine D., Loftus, Joseph P., Yang, Scarlett Y., Asnani, Mukta, King Sainos, Patricia, Pillai, Vinodh, Chong, Emeline, Li, Marilyn M., Tasian, Sarah K., Barash, Yoseph, Lieberman, Paul M., Ruella, Marco, Schuster, Stephen J., Thomas-Tikhonenko, Andrei
Publicado 2023