Phenotype Prediction Using Regularized Regression on Genetic Data in the DREAM5 Systems Genetics B Challenge

por Loh, Po-Ru, Tucker, George, Berger, Bonnie
Publicado 2011

A sampling framework for incorporating quantitative mass spectrometry data in protein interaction analysis

por Tucker, George, Loh, Po-Ru, Berger, Bonnie
Publicado 2013

Fast and accurate long-range phasing in a UK Biobank cohort

por Loh, Po-Ru, Palamara, Pier Francesco, Price, Alkes L
Publicado 2016

Monogenic and polygenic inheritance become instruments for clonal selection

por Loh, Po-Ru, Genovese, Giulio, McCarroll, Steven A
Publicado 2020

Assessing statistical significance in causal graphs

por Chindelevitch, Leonid, Loh, Po-Ru, Enayetallah, Ahmed, Berger, Bonnie, Ziemek, Daniel
Publicado 2012

Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses

por Barton, Alison R., Sherman, Maxwell A., Mukamel, Ronen E., Loh, Po-Ru
Publicado 2021

Efficient Moment-Based Inference of Admixture Parameters and Sources of Gene Flow

por Lipson, Mark, Loh, Po-Ru, Levin, Alex, Reich, David, Patterson, Nick, Berger, Bonnie
Publicado 2013

Calibrating the Human Mutation Rate via Ancestral Recombination Density in Diploid Genomes

por Lipson, Mark, Loh, Po-Ru, Sankararaman, Sriram, Patterson, Nick, Berger, Bonnie, Reich, David
Publicado 2015

Incorporating family history of disease improves polygenic risk scores in diverse populations

por Hujoel, Margaux L.A., Loh, Po-Ru, Neale, Benjamin M., Price, Alkes L.
Publicado 2022

Liability threshold modeling of case-control status and family history of disease increases association power

por Hujoel, Margaux L.A., Gazal, Steven, Loh, Po-Ru, Patterson, Nick, Price, Alkes L.
Publicado 2020

A model and test for coordinated polygenic epistasis in complex traits

por Sheppard, Brooke, Rappoport, Nadav, Loh, Po-Ru, Sanders, Stephan J., Zaitlen, Noah, Dahl, Andy
Publicado 2021

Genome-wide mapping of somatic mutation rates uncovers drivers of cancer

por Sherman, Maxwell A., Yaari, Adam U., Priebe, Oliver, Dietlein, Felix, Loh, Po-Ru, Berger, Bonnie
Publicado 2022

Inferring Admixture Histories of Human Populations Using Linkage Disequilibrium

por Loh, Po-Ru, Lipson, Mark, Patterson, Nick, Moorjani, Priya, Pickrell, Joseph K., Reich, David, Berger, Bonnie
Publicado 2013

Functional architecture of low-frequency variants highlights strength of negative selection across coding and noncoding annotations

por Gazal, Steven, Loh, Po-Ru, Finucane, Hilary K., Ganna, Andrea, Schoech, Armin, Sunyaev, Shamil, Price, Alkes L.
Publicado 2018

Efficient cross-trait penalized regression increases prediction accuracy in large cohorts using secondary phenotypes

por Chung, Wonil, Chen, Jun, Turman, Constance, Lindstrom, Sara, Zhu, Zhaozhong, Loh, Po-Ru, Kraft, Peter, Liang, Liming
Publicado 2019

Estimating the effective sample size in association studies of quantitative traits

por Ziyatdinov, Andrey, Kim, Jihye, Prokopenko, Dmitry, Privé, Florian, Laporte, Fabien, Loh, Po-Ru, Kraft, Peter, Aschard, Hugues
Publicado 2021

Incorporating functional priors improves polygenic prediction accuracy in UK Biobank and 23andMe data sets

por Márquez-Luna, Carla, Gazal, Steven, Loh, Po-Ru, Kim, Samuel S., Furlotte, Nicholas, Auton, Adam, Price, Alkes L.
Publicado 2021

Reconstructing Austronesian population history in Island Southeast Asia

por Lipson, Mark, Loh, Po-Ru, Patterson, Nick, Moorjani, Priya, Ko, Ying-Chin, Stoneking, Mark, Berger, Bonnie, Reich, David
Publicado 2014

Genetically predicted telomere length is associated with clonal somatic copy number alterations in peripheral leukocytes

por Brown, Derek W., Lin, Shu-Hong, Loh, Po-Ru, Chanock, Stephen J., Savage, Sharon A., Machiela, Mitchell J.
Publicado 2020

A genome-wide cross trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases

por Zhu, Zhaozhong, Lee, Phil H., Chaffin, Mark D., Chung, Wonil, Loh, Po-Ru, Lu, Quan, Christiani, David C., Liang, Liming
Publicado 2018