Lipid-Lowering Drug Effects Beyond the Cardiovascular System: Relevance for Neuropsychiatric Disorders

por Lohoff, Falk W
Publicado 2018

Targeting Unmet Clinical Needs in the Treatment of Alcohol Use Disorder

por Lohoff, Falk W.
Publicado 2022

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in the Brain and Relevance for Neuropsychiatric Disorders

por O’Connell, Emma M., Lohoff, Falk W.
Publicado 2020

A genetically-informed study disentangling the relationships between tobacco smoking, cannabis use, alcohol consumption, substance use disorders and respiratory infections, includi...

por Rosoff, Daniel B., Yoo, Joyce, Lohoff, Falk W.
Publicado 2021

Smoking is significantly associated with increased risk of COVID-19 and other respiratory infections

por Rosoff, Daniel B., Yoo, Joyce, Lohoff, Falk W.
Publicado 2021

Prescription Opioid Use and Risk for Major Depressive Disorder and Anxiety and Stress-Related Disorders: A Multivariable Mendelian Randomization Analysis

por Rosoff, Daniel B., Smith, George Davey, Lohoff, Falk W.
Publicado 2020

Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling

por Longley, Martha J., Lee, Jisoo, Jung, Jeesun, Lohoff, Falk W.
Publicado 2021

PCSK9 and the Gut-Liver-Brain Axis: A Novel Therapeutic Target for Immune Regulation in Alcohol Use Disorder

por Lee, Ji Soo, O’Connell, Emma M., Pacher, Pal, Lohoff, Falk W.
Publicado 2021

COMT and ANKK1-Taq-Ia Genetic Polymorphisms Influence Visual Working Memory

por Berryhill, Marian E., Wiener, Martin, Stephens, Jaclyn A., Lohoff, Falk W., Coslett, H. Branch
Publicado 2013

The major depressive disorder GWAS-supported variant rs10514299 in TMEM161B-MEF2C predicts putamen activation during reward processing in alcohol dependence

por Muench, Christine, Schwandt, Melanie, Jung, Jeesun, Cortes, Carlos R., Momenan, Reza, Lohoff, Falk W.
Publicado 2018

Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study

por Rosoff, Daniel B., Davey Smith, George, Mehta, Nehal, Clarke, Toni-Kim, Lohoff, Falk W.
Publicado 2020

Multi-omic underpinnings of epigenetic aging and human longevity

por Mavromatis, Lucas A., Rosoff, Daniel B., Bell, Andrew S., Jung, Jeesun, Wagner, Josephin, Lohoff, Falk W.
Publicado 2023

Comparing the Relationships of Genetically Proxied PCSK9 Inhibition With Mood Disorders, Cognition, and Dementia Between Men and Women: A Drug‐Target Mendelian Randomization Study...

por Bell, Andrew S., Rosoff, Daniel B., Mavromatis, Lucas A., Jung, Jeesun, Wagner, Josephin, Lohoff, Falk W.
Publicado 2022

Educational attainment reduces the risk of suicide attempt among individuals with and without psychiatric disorders independent of cognition: a bidirectional and multivariable Mend...

por Rosoff, Daniel B., Kaminsky, Zachary A., McIntosh, Andrew M., Davey Smith, George, Lohoff, Falk W.
Publicado 2020

Association Between Brain Structure and Alcohol Use Behaviors in Adults: A Mendelian Randomization and Multiomics Study

por Mavromatis, Lucas A., Rosoff, Daniel B., Cupertino, Renata B., Garavan, Hugh, Mackey, Scott, Lohoff, Falk W.
Publicado 2022

Volumetric Prefrontal Cortex Alterations in Patients With Alcohol Dependence and the Involvement of Self-Control

por Rosenthal, Annika, Beck, Anne, Zois, Evangelos, Vollstädt-Klein, Sabine, Walter, Henrik, Kiefer, Falk, Lohoff, Falk W., Charlet, Katrin
Publicado 2019

Assessing the Impact of PCSK9 and HMGCR Inhibition on Liver Function: Drug-Target Mendelian Randomization Analyses in Four Ancestries

por Rosoff, Daniel B., Bell, Andrew S., Wagner, Josephin, Mavromatis, Lucas A., Hamandi, Ali, Park, Lauren, Jung, Jeesun, Lohoff, Falk W.
Publicado 2023

Association of High-Intensity Binge Drinking With Lipid and Liver Function Enzyme Levels

por Rosoff, Daniel B., Charlet, Katrin, Jung, Jeesun, Lee, Jisoo, Muench, Christine, Luo, Audrey, Longley, Martha, Mauro, Kelsey L., Lohoff, Falk W.
Publicado 2019

Educational attainment impacts drinking behaviors and risk for alcohol dependence: results from a two-sample Mendelian randomization study with ~780,000 participants

por Rosoff, Daniel B., Clarke, Toni-Kim, Adams, Mark J., McIntosh, Andrew M., Davey Smith, George, Jung, Jeesun, Lohoff, Falk W.
Publicado 2019

Multivariate genome-wide analysis of aging-related traits identifies novel loci and new drug targets for healthy aging

por Rosoff, Daniel B., Mavromatis, Lucas A., Bell, Andrew S., Wagner, Josephin, Jung, Jeesun, Marioni, Riccardo E., Davey Smith, George, Horvath, Steve, Lohoff, Falk W.
Publicado 2023