Animal-Free Chemical Safety Assessment

por Loizou, George D.
Publicado 2016

MEGen: A Physiologically Based Pharmacokinetic Model Generator

por Loizou, George, Hogg, Alex
Publicado 2011

Editorial: Application of computational tools to health and environmental sciences, Volume II

por Ruiz, Patricia, Loizou, George
Publicado 2022

Editorial: 3Rs—Strategies for reduction and refinement of animal studies

por Fröhlich, Eleonore, Loizou, George D.
Publicado 2023

Refinement and calibration of a human PBPK model for the plasticiser, Di-(2-propylheptyl) phthalate (DPHP) using in silico, in vitro and human biomonitoring data

por McNally, Kevin, Loizou, George
Publicado 2023

A probabilistic model of human variability in physiology for future application to dose reconstruction and QIVIVE

por McNally, Kevin, Loizou, George D.
Publicado 2015

Development, testing, parameterisation, and calibration of a human PBK model for the plasticiser, di (2-ethylhexyl) adipate (DEHA) using in silico, in vitro and human biomonitoring...

por McNally, Kevin, Sams, Craig, Loizou, George
Publicado 2023

A Computational Workflow for Probabilistic Quantitative in Vitro to in Vivo Extrapolation

por McNally, Kevin, Hogg, Alex, Loizou, George
Publicado 2018

Development, Testing, Parameterization, and Calibration of a Human Physiologically Based Pharmacokinetic Model for the Plasticizer, Hexamoll(®) Diisononyl-Cyclohexane-1, 2-Dicarbox...

por McNally, Kevin, Sams, Craig, Loizou, George
Publicado 2019

A Workflow for Global Sensitivity Analysis of PBPK Models

por McNally, Kevin, Cotton, Richard, Loizou, George D.
Publicado 2011

Derivation of a Human In Vivo Benchmark Dose for Bisphenol A from ToxCast In Vitro Concentration Response Data Using a Computational Workflow for Probabilistic Quantitative In Vitr...

por Loizou, George, McNally, Kevin, Paini, Alicia, Hogg, Alex
Publicado 2022

Development, testing, parameterisation, and calibration of a human PBPK model for the plasticiser, di-(2-ethylhexyl) terephthalate (DEHTP) using in silico, in vitro and human biomo...

por McNally, Kevin, Sams, Craig, Hogg, Alex, Loizou, George
Publicado 2023

The application of global sensitivity analysis in the development of a physiologically based pharmacokinetic model for m-xylene and ethanol co-exposure in humans

por Loizou, George D., McNally, Kevin, Jones, Kate, Cocker, John
Publicado 2015

Development, Testing, Parameterisation and Calibration of a Human PBPK Model for the Plasticiser, Di-(2-propylheptyl) Phthalate (DPHP) Using in Silico, in vitro and Human Biomonito...

por McNally, Kevin, Sams, Craig, Hogg, Alex, Lumen, Annie, Loizou, George
Publicado 2021

Derivation of a Human In Vivo Benchmark Dose for Perfluorooctanoic Acid From ToxCast In Vitro Concentration–Response Data Using a Computational Workflow for Probabilistic Quantitat...

por Loizou, George, McNally, Kevin, Dorne, Jean-Lou C. M., Hogg, Alex
Publicado 2021

Quantitative global sensitivity analysis of a biologically based dose-response pregnancy model for the thyroid endocrine system

por Lumen, Annie, McNally, Kevin, George, Nysia, Fisher, Jeffrey W., Loizou, George D.
Publicado 2015

Reconstruction of Exposure to m-Xylene from Human Biomonitoring Data Using PBPK Modelling, Bayesian Inference, and Markov Chain Monte Carlo Simulation

por McNally, Kevin, Cotton, Richard, Cocker, John, Jones, Kate, Bartels, Mike, Rick, David, Price, Paul, Loizou, George
Publicado 2012

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

por Viant, Mark R., Ebbels, Timothy M. D., Beger, Richard D., Ekman, Drew R., Epps, David J. T., Kamp, Hennicke, Leonards, Pim E. G., Loizou, George D., MacRae, James I., van Ravenzwaay, Bennard, Rocca-Serra, Philippe, Salek, Reza M., Walk, Tilmann, Weber, Ralf J. M.
Publicado 2019