An NTD supersite of attack

por Lok, Shee-Mei
Publicado 2021

Common Features of Enveloped Viruses and Implications for Immunogen Design for Next-Generation Vaccines

por Rey, Felix A., Lok, Shee-Mei
Publicado 2018

Capsid protein is central to the birth of flavivirus particles

por Tan, Ter Yong, Fibriansah, Guntur, Lok, Shee-Mei
Publicado 2020

Morphological Diversity and Dynamics of Dengue Virus Affecting Antigenicity

por Fibriansah, Guntur, Lim, Xin-Ni, Lok, Shee-Mei
Publicado 2021

Conformational changes in intact dengue virus reveal serotype-specific expansion

por Lim, Xin-Xiang, Chandramohan, Arun, Lim, Xin Ying Elisa, Bag, Nirmalya, Sharma, Kamal Kant, Wirawan, Melissa, Wohland, Thorsten, Lok, Shee-Mei, Anand, Ganesh S.
Publicado 2017

Structural basis of Chikungunya virus inhibition by monoclonal antibodies

por Zhou, Qun Fei, Fox, Julie M., Earnest, James T., Ng, Thiam-Seng, Kim, Arthur S., Fibriansah, Guntur, Kostyuchenko, Victor A., Shi, Jian, Shu, Bo, Diamond, Michael S., Lok, Shee-Mei
Publicado 2020

Structural Optimization and De Novo Design of Dengue Virus Entry Inhibitory Peptides

por Costin, Joshua M., Jenwitheesuk, Ekachai, Lok, Shee-Mei, Hunsperger, Elizabeth, Conrads, Kelly A., Fontaine, Krystal A., Rees, Craig R., Rossmann, Michael G., Isern, Sharon, Samudrala, Ram, Michael, Scott F.
Publicado 2010

Neutralization mechanism of a highly potent antibody against Zika virus

por Zhang, Shuijun, Kostyuchenko, Victor A., Ng, Thiam-Seng, Lim, Xin-Ni, Ooi, Justin S. G., Lambert, Sebastian, Tan, Ter Yong, Widman, Douglas G., Shi, Jian, Baric, Ralph S., Lok, Shee-Mei
Publicado 2016

CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever

por Shu, Bo, Ooi, Justin S. G., Tan, Aaron W. K., Ng, Thiam-Seng, Dejnirattisai, Wanwisa, Mongkolsapaya, Juthathip, Fibriansah, Guntur, Shi, Jian, Kostyuchenko, Victor A., Screaton, Gavin R., Lok, Shee-Mei
Publicado 2022

2′-O Methylation of Internal Adenosine by Flavivirus NS5 Methyltransferase

por Dong, Hongping, Chang, David C., Hua, Maggie Ho Chia, Lim, Siew Pheng, Chionh, Yok Hian, Hia, Fabian, Lee, Yie Hou, Kukkaro, Petra, Lok, Shee-Mei, Dedon, Peter C., Shi, Pei-Yong
Publicado 2012

A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

por Fibriansah, Guntur, Tan, Joanne L., Smith, Scott A., de Alwis, Ruklanthi, Ng, Thiam-Seng, Kostyuchenko, Victor A., Jadi, Ramesh S., Kukkaro, Petra, de Silva, Aravinda M., Crowe, James E., Lok, Shee-Mei
Publicado 2015

Molecular basis of dengue virus serotype 2 morphological switch from 29°C to 37°C

por Lim, Xin-Ni, Shan, Chao, Marzinek, Jan K., Dong, Hongping, Ng, Thiam Seng, Ooi, Justin S. G., Fibriansah, Guntur, Wang, Jiaqi, Verma, Chandra S., Bond, Peter J., Shi, Pei-Yong, Lok, Shee-mei
Publicado 2019

Capsid protein structure in Zika virus reveals the flavivirus assembly process

por Tan, Ter Yong, Fibriansah, Guntur, Kostyuchenko, Victor A., Ng, Thiam-Seng, Lim, Xin-Xiang, Zhang, Shuijun, Lim, Xin-Ni, Wang, Jiaqi, Shi, Jian, Morais, Marc C., Corti, Davide, Lok, Shee-Mei
Publicado 2020

A potent anti-dengue human antibody preferentially recognizes the conformation of E protein monomers assembled on the virus surface

por Fibriansah, Guntur, Tan, Joanne L, Smith, Scott A, Alwis, Adamberage R, Ng, Thiam-Seng, Kostyuchenko, Victor A, Ibarra, Kristie D, Wang, Jiaqi, Harris, Eva, Silva, Aravinda, Crowe, James E, Lok, Shee-Mei
Publicado 2014

A Human PrM Antibody That Recognizes a Novel Cryptic Epitope on Dengue E Glycoprotein

por Chan, Annie Hoi Yi, Tan, Hwee Cheng, Chow, Angelia Yee, Lim, Angeline Pei Chiew, Lok, Shee Mei, Moreland, Nicole J., Vasudevan, Subhash G., MacAry, Paul A., Ooi, Eng Eong, Hanson, Brendon J.
Publicado 2012

Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus

por Adams, Cameron, Carbaugh, Derek L., Shu, Bo, Ng, Thiam-Seng, Castillo, Izabella N., Bhowmik, Ryan, Segovia-Chumbez, Bruno, Puhl, Ana C., Graham, Stephen, Diehl, Sean A., Lazear, Helen M., Lok, Shee-mei, de Silva, Aravinda M., Premkumar, Lakshmanane
Publicado 2023

Antibody affinity versus dengue morphology influences neutralization

por Fibriansah, Guntur, Lim, Elisa X. Y., Marzinek, Jan K., Ng, Thiam-Seng, Tan, Joanne L., Huber, Roland G., Lim, Xin-Ni, Chew, Valerie S. Y., Kostyuchenko, Victor A., Shi, Jian, Anand, Ganesh S., Bond, Peter J., Crowe, James E., Lok, Shee-Mei
Publicado 2021

Release of Dengue Virus Genome Induced by a Peptide Inhibitor

por Lok, Shee-Mei, Costin, Joshua M., Hrobowski, Yancey M., Hoffmann, Andrew R., Rowe, Dawne K., Kukkaro, Petra, Holdaway, Heather, Chipman, Paul, Fontaine, Krystal A., Holbrook, Michael R., Garry, Robert F., Kostyuchenko, Victor, Wimley, William C., Isern, Sharon, Rossmann, Michael G., Michael, Scott F.
Publicado 2012

High flavivirus structural plasticity demonstrated by a non-spherical morphological variant

por Morrone, Seamus R., Chew, Valerie S. Y., Lim, Xin-Ni, Ng, Thiam-Seng, Kostyuchenko, Victor A., Zhang, Shuijun, Wirawan, Melissa, Chew, Pau-Ling, Lee, Jaime, Tan, Joanne L., Wang, Jiaqi, Tan, Ter Yong, Shi, Jian, Screaton, Gavin, Morais, Marc C., Lok, Shee-Mei
Publicado 2020