Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues

por Okunola-Bakare, Oluyomi M., Cao, Jianjing, Kopajtic, Theresa, Katz, Jonathan L., Loland, Claus J., Shi, Lei, Newman, Amy Hauck
Publicado 2014

Substrate-modulated unwinding of transmembrane helices in the NSS transporter LeuT

por Merkle, Patrick S., Gotfryd, Kamil, Cuendet, Michel A., Leth-Espensen, Katrine Z., Gether, Ulrik, Loland, Claus J., Rand, Kasper D.
Publicado 2018

Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter

por Billesbølle, Christian B., Mortensen, Jonas S., Sohail, Azmat, Schmidt, Solveig G., Shi, Lei, Sitte, Harald H., Gether, Ulrik, Loland, Claus J.
Publicado 2016

Conformational dynamics of the human serotonin transporter during substrate and drug binding

por Möller, Ingvar R., Slivacka, Marika, Nielsen, Anne Kathrine, Rasmussen, Søren G. F., Gether, Ulrik, Loland, Claus J., Rand, Kasper D.
Publicado 2019

Substrate-induced conformational dynamics of the dopamine transporter

por Nielsen, Anne Kathrine, Möller, Ingvar R., Wang, Yong, Rasmussen, Søren G. F., Lindorff-Larsen, Kresten, Rand, Kasper D., Loland, Claus J.
Publicado 2019

The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter

por Plenge, Per, Abramyan, Ara M., Sørensen, Gunnar, Mørk, Arne, Weikop, Pia, Gether, Ulrik, Bang-Andersen, Benny, Shi, Lei, Loland, Claus J.
Publicado 2020

A class of rigid linker-bearing glucosides for membrane protein structural study

por Sadaf, Aiman, Mortensen, Jonas S., Capaldi, Stefano, Tikhonova, Elena, Hariharan, Parameswaran, Ribeiro, Orquidea, Loland, Claus J., Guan, Lan, Byrne, Bernadette, Chae, Pil Seok
Publicado 2016

The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter

por Plenge, Per, Yang, Dongxue, Salomon, Kristine, Laursen, Louise, Kalenderoglou, Iris E., Newman, Amy H., Gouaux, Eric, Coleman, Jonathan A., Loland, Claus J.
Publicado 2021

Butane-1,2,3,4-tetraol-based amphiphilic stereoisomers for membrane protein study: importance of chirality in the linker region

por Das, Manabendra, Du, Yang, Mortensen, Jonas S., Ribeiro, Orquidea, Hariharan, Parameswaran, Guan, Lan, Loland, Claus J., Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Publicado 2017

Mechanism of the Association between Na(+) Binding and Conformations at the Intracellular Gate in Neurotransmitter:Sodium Symporters

por Stolzenberg, Sebastian, Quick, Matthias, Zhao, Chunfeng, Gotfryd, Kamil, Khelashvili, George, Gether, Ulrik, Loland, Claus J., Javitch, Jonathan A., Noskov, Sergei, Weinstein, Harel, Shi, Lei
Publicado 2015

Tris(hydroxymethyl)aminomethane Linker-Bearing Triazine-Based Triglucosides for Solubilization and Stabilization of Membrane Proteins

por Ghani, Lubna, Zhang, Xiang, Munk, Chastine F., Hariharan, Parameswaran, Lan, Baoliang, Yun, Hong Sik, Byrne, Bernadette, Guan, Lan, Loland, Claus J., Liu, Xiangyu, Chae, Pil Seok
Publicado 2023

The Environment Shapes the Inner Vestibule of LeuT

por Sohail, Azmat, Jayaraman, Kumaresan, Venkatesan, Santhoshkannan, Gotfryd, Kamil, Daerr, Markus, Gether, Ulrik, Loland, Claus J., Wanner, Klaus T., Freissmuth, Michael, Sitte, Harald H., Sandtner, Walter, Stockner, Thomas
Publicado 2016

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR

por Erlendsson, Simon, Gotfryd, Kamil, Larsen, Flemming Hofmann, Mortensen, Jonas Sigurd, Geiger, Michel-Andreas, van Rossum, Barth-Jan, Oschkinat, Hartmut, Gether, Ulrik, Teilum, Kaare, Loland, Claus J
Publicado 2017

Tandem malonate-based glucosides (TMGs) for membrane protein structural studies

por Hussain, Hazrat, Mortensen, Jonas S., Du, Yang, Santillan, Claudia, Ribeiro, Orquidea, Go, Juyeon, Hariharan, Parameswaran, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Byrne, Bernadette, Chae, Pil Seok
Publicado 2017

Melamine-cored glucosides for membrane protein solubilization and stabilization: importance of water-mediated intermolecular hydrogen bonding in detergent performance

por Ghani, Lubna, Kim, Seonghoon, Ehsan, Muhammad, Lan, Baoliang, Poulsen, Ida H., Dev, Chandra, Katsube, Satoshi, Byrne, Bernadette, Guan, Lan, Loland, Claus J., Liu, Xiangyu, Im, Wonpil, Chae, Pil Seok
Publicado 2023

The dopamine transporter antiports potassium to increase the uptake of dopamine

por Schmidt, Solveig G., Malle, Mette Galsgaard, Nielsen, Anne Kathrine, Bohr, Søren S.-R., Pugh, Ciara F., Nielsen, Jeppe C., Poulsen, Ida H., Rand, Kasper D., Hatzakis, Nikos S., Loland, Claus J.
Publicado 2022

Dendronic trimaltoside amphiphiles (DTMs) for membrane protein study

por Sadaf, Aiman, Du, Yang, Santillan, Claudia, Mortensen, Jonas S., Molist, Iago, Seven, Alpay B., Hariharan, Parameswaran, Skiniotis, Georgios, Loland, Claus J., Kobilka, Brian K., Guan, Lan, Byrne, Bernadette, Chae, Pil Seok
Publicado 2017

Asymmetric maltose neopentyl glycol amphiphiles for a membrane protein study: effect of detergent asymmetricity on protein stability

por Bae, Hyoung Eun, Du, Yang, Hariharan, Parameswaran, Mortensen, Jonas S., Kumar, Kaavya K., Ha, Betty, Das, Manabendra, Lee, Hyun Sung, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Chae, Pil Seok
Publicado 2018

Development of 1,3-acetonedicarboxylate-derived glucoside amphiphiles (ACAs) for membrane protein study

por Lee, Ho Jin, Ehsan, Muhammad, Zhang, Xiang, Katsube, Satoshi, Munk, Chastine F., Wang, Haoqing, Ahmed, Waqar, Kumar, Ashwani, Byrne, Bernadette, Loland, Claus J., Guan, Lan, Liu, Xiangyu, Chae, Pil Seok
Publicado 2022

Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila

por Gericke, Oliver, Fowler, Rachael M., Heskes, Allison M., Bayly, Michael J., Semple, Susan J., Ndi, Chi P., Stærk, Dan, Løland, Claus J., Murphy, Daniel J., Buirchell, Bevan J., Møller, Birger Lindberg
Publicado 2021