Collateral Victim or Rescue Worker?—The Role of Histone Methyltransferases in DNA Damage Repair and Their Targeting for Therapeutic Opportunities in Cancer

por He, Lishu, Lomberk, Gwen
Publicado 2021

The Heterochromatin Protein 1 family

por Lomberk, Gwen, Wallrath, Lori, Urrutia, Raul
Publicado 2006

The promise of epigenomic therapeutics in pancreatic cancer

por Lomberk, Gwen A, Iovanna, Juan, Urrutia, Raul
Publicado 2016

Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine

por Lomberk, Gwen, Dusetti, Nelson, Iovanna, Juan, Urrutia, Raul
Publicado 2019

Resolution of Cochlear Inflammation: Novel Target for Preventing or Ameliorating Drug-, Noise- and Age-related Hearing Loss

por Kalinec, Gilda M., Lomberk, Gwen, Urrutia, Raul A., Kalinec, Federico
Publicado 2017

Silencing of the Transforming Growth Factor-β (TGFβ) Receptor II by Krüppel-like Factor 14 Underscores the Importance of a Negative Feedback Mechanism in TGFβ Signaling

por Truty, Mark J., Lomberk, Gwen, Fernandez-Zapico, Martin E., Urrutia, Raul
Publicado 2009

Single and combinatorial chromatin coupling events underlies the function of transcript factor krüppel-like factor 11 in the regulation of gene networks

por Calvo, Ezequiel, Grzenda, Adrienne, Lomberk, Gwen, Mathison, Angela, Iovanna, Juan, Urrutia, Raul
Publicado 2014

Evidence supporting the existence of a NUPR1-like family of helix-loop-helix chromatin proteins related to, yet distinct from, AT hook-containing HMG proteins

por Urrutia, Raul, Velez, Gabriel, Lin, Marisa, Lomberk, Gwen, Neira, Jose Luis, Iovanna, Juan
Publicado 2014

Evidence supporting a critical contribution of intrinsically disordered regions to the biochemical behavior of full-length human HP1γ

por Velez, Gabriel, Lin, Marisa, Christensen, Trace, Faubion, William A., Lomberk, Gwen, Urrutia, Raul
Publicado 2015

LSD1, a double-edged sword, confers dynamic chromatin regulation but commonly promotes aberrant cell growth

por Kozub, Meghan M, Carr, Ryan M, Lomberk, Gwen L, Fernandez-Zapico, Martin E
Publicado 2017

Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers

por Zimmermann, Michael T., Williams, Monique M., Klee, Eric W., Lomberk, Gwen A., Urrutia, Raul
Publicado 2019

MAGE I Transcription Factors Regulate KAP1 and KRAB Domain Zinc Finger Transcription Factor Mediated Gene Repression

por Xiao, Tony Z., Bhatia, Neehar, Urrutia, Raul, Lomberk, Gwen A., Simpson, Andrew, Longley, B. Jack
Publicado 2011

Adapting Mentoring in Times of Crisis: What We Learned from COVID-19

por Tetzlaff, Julie, Lomberk, Gwen, Smith, Heather M., Agrawal, Himanshu, Siegel, Dawn H., Apps, Jennifer N.
Publicado 2022

Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain

por Mathison, Angela, Milech De Assuncao, Thiago, Dsouza, Nikita R., Williams, Monique, Zimmermann, Michael T., Urrutia, Raul, Lomberk, Gwen
Publicado 2020

Precision medicine in trauma: a transformational frontier in patient care, education, and research

por Davis, Christopher Stephen, Wilkinson, Katheryn Hope, Lin, Emily, Carpenter, Nathaniel James, Georgeades, Christina, Lomberk, Gwen, Urrutia, Raul
Publicado 2021

Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression

por Grzenda, Adrienne, Lomberk, Gwen, Svingen, Phyllis, Mathison, Angela, Calvo, Ezequiel, Iovanna, Juan, Xiong, Yuning, Faubion, William, Urrutia, Raul
Publicado 2013

Pancreatitis promotes oncogenic Kras(G12D)-induced pancreatic transformation through activation of Nupr1

por Grasso, Daniel, Garcia, Maria Noé, Hamidi, Tewfik, Cano, Carla, Calvo, Ezequiel, Lomberk, Gwen, Urrutia, Raul, Iovanna, Juan L
Publicado 2014

Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression

por Grzenda, Adrienne, Leonard, Phoebe, Seo, Seungmae, Mathison, Angela J, Urrutia, Guillermo, Calvo, Ezequiel, Iovanna, Juan, Urrutia, Raul, Lomberk, Gwen
Publicado 2013

Krüppel-like Factor 11 Differentially Couples to Histone Acetyltransferase and Histone Methyltransferase Chromatin Remodeling Pathways to Transcriptionally Regulate Dopamine D2 Rec...

por Seo, Seungmae, Lomberk, Gwen, Mathison, Angela, Buttar, Navtej, Podratz, Jewel, Calvo, Ezequiel, Iovanna, Juan, Brimijoin, Stephen, Windebank, Anthony, Urrutia, Raul
Publicado 2012

Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway

por Seo, Seungmae, Mathison, Angela, Grzenda, Adrienne, Podratz, Jewel, Calvo, Ezequiel, Brimijoin, Stephen, Windebank, Anthony, Iovanna, Juan, Lomberk, Gwen, Urrutia, Raul
Publicado 2018