The promise of epigenomic therapeutics in pancreatic cancer

por Lomberk, Gwen A, Iovanna, Juan, Urrutia, Raul
Publicado 2016

Modeling post‐translational modifications and cancer‐associated mutations that impact the heterochromatin protein 1α‐importin α heterodimers

por Zimmermann, Michael T., Williams, Monique M., Klee, Eric W., Lomberk, Gwen A., Urrutia, Raul
Publicado 2019

MAGE I Transcription Factors Regulate KAP1 and KRAB Domain Zinc Finger Transcription Factor Mediated Gene Repression

por Xiao, Tony Z., Bhatia, Neehar, Urrutia, Raul, Lomberk, Gwen A., Simpson, Andrew, Longley, B. Jack
Publicado 2011

A novel de novo frameshift deletion in EHMT1 in a patient with Kleefstra Syndrome results in decreased H3K9 dimethylation

por Blackburn, Patrick R., Williams, Monique, Cousin, Margot A., Boczek, Nicole J., Beek, Geoffrey J., Lomberk, Gwen A., Urrutia, Raul A., Babovic‐Vuksanovic, Dusica, Klee, Eric W.
Publicado 2017

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability

por Williams, Monique M., Mathison, Angela J., Christensen, Trent, Greipp, Patricia T., Knutson, Darlene L., Klee, Eric W., Zimmermann, Michael T., Iovanna, Juan, Lomberk, Gwen A., Urrutia, Raul A.
Publicado 2019

A Novel Role of the Sp/KLF Transcription Factor KLF11 in Arresting Progression of Endometriosis

por Daftary, Gaurang S., Zheng, Ye, Tabbaa, Zaid M., Schoolmeester, John K., Gada, Ravi P., Grzenda, Adrienne L., Mathison, Angela J., Keeney, Gary L., Lomberk, Gwen A., Urrutia, Raul
Publicado 2013

KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress

por Yang, Yizeng, Bhargava, Dharmendra, Chen, Xiao, Zhou, Taicheng, Dursuk, Gizem, Jiang, Wenpeng, Wang, Jinshen, Zong, Zhen, Katz, Sharyn I., Lomberk, Gwen A., Urrutia, Raul A., Katz, Jonathan P.
Publicado 2023

Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys–Dietz syndrome (LDS) impairs canonical TGF-β signaling

por Cousin, Margot A., Zimmermann, Michael T., Mathison, Angela J., Blackburn, Patrick R., Boczek, Nicole J., Oliver, Gavin R., Lomberk, Gwen A., Urrutia, Raul A., Deyle, David R., Klee, Eric W.
Publicado 2017

Co-occurrence of a maternally inherited DNMT3A duplication and a paternally inherited pathogenic variant in EZH2 in a child with growth retardation and severe short stature: atypic...

por Polonis, Katarzyna, Blackburn, Patrick R., Urrutia, Raul A., Lomberk, Gwen A., Kruisselbrink, Teresa, Cousin, Margot A., Boczek, Nicole J., Hoppman, Nicole L., Babovic-Vuksanovic, Dusica, Klee, Eric W., Pichurin, Pavel N.
Publicado 2018

Aurora-A Mitotic Kinase Induces Endocrine Resistance through Down-Regulation of ERα Expression in Initially ERα+ Breast Cancer Cells

por Opyrchal, Mateusz, Salisbury, Jeffrey L., Zhang, Shuya, McCubrey, James, Hawse, John, Goetz, Mattew P., Lomberk, Gwen A., Haddad, Tufia, Degnim, Amy, Lange, Carol, Ingle, James N., Galanis, Evanthia, D'Assoro, Antonino B.
Publicado 2014

Detailed Structural-Functional Analysis of the Krüppel-like Factor 16 (KLF16) Transcription Factor Reveals Novel Mechanisms for Silencing Sp/KLF Sites Involved in Metabolism and En...

por Daftary, Gaurang S., Lomberk, Gwen A., Buttar, Navtej S., Allen, Thomas W., Grzenda, Adrienne, Zhang, Jinsan, Zheng, Ye, Mathison, Angela J., Gada, Ravi P., Calvo, Ezequiel, Iovanna, Juan L., Billadeau, Daniel D., Prendergast, Franklyn G., Urrutia, Raul
Publicado 2012

Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Cholangiocytes

por De Assuncao, Thiago M., Sun, Yan, Jalan-Sakrikar, Nidhi, Drinane, Mary, Huang, Bing Q., Li, Ying, Davila, Jaime I., Wang, Ruisi, O’Hara, Steven P., Lomberk, Gwen A., Urrutia, Raul A., Ikeda, Yasuhiro, Huebert, Robert C.
Publicado 2015

Membrane-To-Nucleus Signaling Links Insulin-Like Growth Factor-1- and Stem Cell Factor-Activated Pathways

por Hayashi, Yujiro, Asuzu, David T., Gibbons, Simon J., Aarsvold, Kirsten H., Bardsley, Michael R., Lomberk, Gwen A., Mathison, Angela J., Kendrick, Michael L., Shen, K. Robert, Taguchi, Takahiro, Gupta, Anu, Rubin, Brian P., Fletcher, Jonathan A., Farrugia, Gianrico, Urrutia, Raul A., Ordog, Tamas
Publicado 2013

A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

por Kloesch, Bernhard, Ionasz, Vivien, Paliwal, Sumit, Hruschka, Natascha, Martinez de Villarreal, Jaime, Öllinger, Rupert, Mueller, Sebastian, Dienes, Hans Peter, Schindl, Martin, Gruber, Elisabeth S, Stift, Judith, Herndler-Brandstetter, Dietmar, Lomberk, Gwen A, Seidler, Barbara, Saur, Dieter, Rad, Roland, Urrutia, Raul A, Real, Francisco X, Martinelli, Paola
Publicado 2022