The Role of Striatal-Enriched Protein Tyrosine Phosphatase (STEP) in Cognition

por Fitzpatrick, Christopher James, Lombroso, Paul J.
Publicado 2011

A Common STEP in the Synaptic Pathology of Diverse Neuropsychiatric Disorders

por Johnson, Micah A., Lombroso, Paul J.
Publicado 2012

Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function

por Kamceva, Marija, Benedict, Jessie, Nairn, Angus C., Lombroso, Paul J.
Publicado 2016

Molecular underpinnings of neurodegenerative disorders: striatal-enriched protein tyrosine phosphatase signaling and synaptic plasticity

por Lombroso, Paul J., Ogren, Marilee, Kurup, Pradeep, Nairn, Angus C.
Publicado 2016

Striatal-Enriched Protein Tyrosine Phosphatase Controls Responses to Aversive Stimuli: Implication for Ethanol Drinking

por Legastelois, Rémi, Darcq, Emmanuel, Wegner, Scott A., Lombroso, Paul J., Ron, Dorit
Publicado 2015

Rapid regulation of endoplasmic reticulum dynamics in dendritic spines by NMDA receptor activation

por Ng, Ai Na, Doherty, Andrew J, Lombroso, Paul J, Emptage, Nigel J, Collingridge, Graham L
Publicado 2014

STEP activation by Gαq coupled GPCRs opposes Src regulation of NMDA receptors containing the GluN2A subunit

por Tian, Meng, Xu, Jian, Lei, Gang, Lombroso, Paul J., Jackson, Michael F., MacDonald, John F.
Publicado 2016

Glutathione-Responsive Selenosulfide Prodrugs as a Platform Strategy for Potent and Selective Mechanism-Based Inhibition of Protein Tyrosine Phosphatases

por Tjin, Caroline Chandra, Otley, Kate D., Baguley, Tyler D., Kurup, Pradeep, Xu, Jian, Nairn, Angus C., Lombroso, Paul J., Ellman, Jonathan A.
Publicado 2017

Loss of STEP(61) couples disinhibition to N-methyl-d-aspartate receptor potentiation in rodent and human spinal pain processing

por Dedek, Annemarie, Xu, Jian, Kandegedara, Chaya M, Lorenzo, Louis-Étienne, Godin, Antoine G, De Koninck, Yves, Lombroso, Paul J, Tsai, Eve C, Hildebrand, Michael E
Publicado 2019

Regulation of STEP(61) and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity

por Jang, Sung-Soo, Royston, Sara E., Xu, Jian, Cavaretta, John P., Vest, Max O., Lee, Kwan Young, Lee, Seungbae, Jeong, Han Gil, Lombroso, Paul J., Chung, Hee Jung
Publicado 2015

Sexual dimorphism in a neuronal mechanism of spinal hyperexcitability across rodent and human models of pathological pain

por Dedek, Annemarie, Xu, Jian, Lorenzo, Louis-Étienne, Godin, Antoine G, Kandegedara, Chaya M, Glavina, Geneviève, Landrigan, Jeffrey A, Lombroso, Paul J, De Koninck, Yves, Tsai, Eve C, Hildebrand, Michael E
Publicado 2022

Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)

por Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent JS De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas DY, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas DP, Tautz, Lutz
Publicado 2021

Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease

por Xu, Jian, Chatterjee, Manavi, Baguley, Tyler D., Brouillette, Jonathan, Kurup, Pradeep, Ghosh, Debolina, Kanyo, Jean, Zhang, Yang, Seyb, Kathleen, Ononenyi, Chimezie, Foscue, Ethan, Anderson, George M., Gresack, Jodi, Cuny, Gregory D., Glicksman, Marcie A., Greengard, Paul, Lam, TuKiet T., Tautz, Lutz, Nairn, Angus C., Ellman, Jonathan A., Lombroso, Paul J.
Publicado 2014