Biochemical Activity of Vaborbactam

por Tsivkovski, Ruslan, Lomovskaya, Olga
Publicado 2020

Potency of Vaborbactam Is Less Affected than That of Avibactam in Strains Producing KPC-2 Mutations That Confer Resistance to Ceftazidime-Avibactam

por Tsivkovski, Ruslan, Lomovskaya, Olga
Publicado 2020

Biochemical Characterization of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases

por Tsivkovski, Ruslan, Totrov, Maxim, Lomovskaya, Olga
Publicado 2020

727. Potency of the β-Lactamase Inhibitor QPX7728 Is Minimally Affected by KPC Mutations that Reduce Potency of Ceftazidime–Avibactam

por Lomovskaya, Olga, Nelson, Kirk J, Rubio-Aparicio, Debora
Publicado 2019

1053. The β-Lactamase Inhibitor QPX7728 Restores the Activity of β-Lactam Agents against Contemporary Extended-Spectrum β-lactamase (ESBL)-Producing and Carbapenem-Resistant Entero...

por Lindley, Jill, Edah, Yahse, Lomovskaya, Olga, Castanheira, Mariana, Castanheira, Mariana
Publicado 2021

690. Activity of a Novel Polymyxin Analog, QPX9003, Tested Against Resistant Gram-Negative Pathogens, Including Carbapenem-Resistant Acinetobacter, Enterobacterales, and Pseudomona...

por Castanheira, Mariana, Lindley, Jill, Huynh, Holly, Mendes, Rodrigo E, Lomovskaya, Olga
Publicado 2019

677. Activity of Novel β-Lactamase Inhibitor QPX7728 Combined with β-Lactam Agents When Tested Against Carbapenem-Resistant Enterobacteriaceae (CRE) Isolates

por Castanheira, Mariana, Lindley, Jill, Huynh, Holly, Mendes, Rodrigo E, Lomovskaya, Olga
Publicado 2019

The Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 Restores the Potency of Multiple Oral Beta-Lactam Antibiotics against Beta-Lactamase-Producing Strains of Resistant Enterob...

por Lomovskaya, Olga, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Loutit, Jeff, Dudley, Michael
Publicado 2022

New boronate drugs and evolving NDM-mediated beta-lactam resistance

por Lomovskaya, Olga, Tsivkovski, Ruslan, Totrov, Maxim, Dressel, Dana, Castanheira, Mariana, Dudley, Michael
Publicado 2023

Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae

por Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Dudley, Michael N., Lomovskaya, Olga
Publicado 2017

681. In vitro Activity of the β-Lactamase Inhibitor QPX7728 in Combination with Several β-Lactams Against Acinetobacter baumannii (AB) and Pseudomonas aeruginosa (PSA)

por Lomovskaya, Olga, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk J, Castanheira, Mariana
Publicado 2019

166. Activity of a Novel β-lactamase Inhibitor QPX7728 Combined With β-lactams Against st258 klebsiella Pneumoniae and st131 escherchia Coli Isolates Producing β-lactamases

por Castanheira, Mariana, Lindley, Jill, Doyle, Timothy B, Davis, Andrew P, Lomovskaya, Olga
Publicado 2020

In Vitro Activity of Meropenem-Vaborbactam against Clinical Isolates of KPC-Positive Enterobacteriaceae

por Hackel, Meredith A., Lomovskaya, Olga, Dudley, Michael N., Karlowsky, James A., Sahm, Daniel F.
Publicado 2017

Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases in Enterobacteriaceae, Pse...

por Lomovskaya, Olga, Nelson, Kirk, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Sun, Dongxu, Dudley, Michael N.
Publicado 2020

Intrinsic Antibacterial Activity of Xeruborbactam In Vitro: Assessing Spectrum and Mode of Action

por Sun, Dongxu, Tsivkovski, Ruslan, Pogliano, Joe, Tsunemoto, Hannah, Nelson, Kirk, Rubio-Aparicio, Debora, Lomovskaya, Olga
Publicado 2022

Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity...

por Lomovskaya, Olga, Tsivkovski, Ruslan, Nelson, Kirk, Rubio-Aparicio, Debora, Sun, Dongxu, Totrov, Maxim, Dudley, Michael N.
Publicado 2020

Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae

por Lomovskaya, Olga, Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Griffith, David C., Dudley, Michael N.
Publicado 2017

QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics

por Lomovskaya, Olga, Tsivkovski, Ruslan, Sun, Dongxu, Reddy, Raja, Totrov, Maxim, Hecker, Scott, Griffith, David, Loutit, Jeffery, Dudley, Michael
Publicado 2021

In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa

por Lomovskaya, Olga, Rubio-Aparicio, Debora, Nelson, Kirk, Sun, Dongxu, Tsivkovski, Ruslan, Castanheira, Mariana, Lindley, Jill, Loutit, Jeffery, Dudley, Michael
Publicado 2021

In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-re...

por Lomovskaya, Olga, Castanheira, Mariana, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Sun, Dongxu, Totrov, Maxim, Loutit, Jeffery, Dudley, Michael
Publicado 2023