The role of Ubiquitination in Apoptosis and Necroptosis

por Roberts, Jamie Z., Crawford, Nyree, Longley, Daniel B.
Publicado 2021

FLIP(L): the pseudo‐caspase

por Smyth, Peter, Sessler, Tamas, Scott, Christopher J., Longley, Daniel B.
Publicado 2020

Therapeutics Targeting the Core Apoptotic Machinery

por Hamilton, Claudia, Fox, Jennifer P., Longley, Daniel B., Higgins, Catherine A.
Publicado 2021

Correction: Hamilton et al. Therapeutics Targeting the Core Apoptotic Machinery. Cancers 2021, 13, 2618

por Hamilton, Claudia, Fox, Jennifer P., Longley, Daniel B., Higgins, Catherine A.
Publicado 2022

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8

por Chacko, Alex D, Liberante, Fabio, Paul, Ian, Longley, Daniel B, Fennell, Dean A
Publicado 2010

Epithelial‐to‐mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition

por McCorry, Amy MB, Loughrey, Maurice B, Longley, Daniel B, Lawler, Mark, Dunne, Philip D
Publicado 2018

Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

por Salvucci, Manuela, Crawford, Nyree, Stott, Katie, Bullman, Susan, Longley, Daniel B, Prehn, Jochen H M
Publicado 2022

Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

por Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Publicado 2012

Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform

por Matveeva, Anna, Fichtner, Michael, McAllister, Katherine, McCann, Christopher, Sturrock, Marc, Longley, Daniel B., Prehn, Jochen H. M.
Publicado 2019

TRAIL signaling promotes entosis in colorectal cancer

por Bozkurt, Emir, Düssmann, Heiko, Salvucci, Manuela, Cavanagh, Brenton L., Van Schaeybroeck, Sandra, Longley, Daniel B., Martin, Seamus J., Prehn, Jochen H.M.
Publicado 2021

Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway

por Stevenson, Leanne, Allen, Wendy L., Proutski, Irina, Stewart, Gail, Johnston, Louise, McCloskey, Karen, Wilson, Peter M., Longley, Daniel B., Johnston, Patrick G.
Publicado 2011

The Colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information

por Allen, Wendy L, Jithesh, Puthen V, Oliver, Gavin R, Proutski, Irina, Longley, Daniel B, Lenz, Heinz-Josef, Proutski, Vitali, Harkin, Paul, Johnston, Patrick G
Publicado 2010

classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes

por Quinn, Gerard P., Sessler, Tamas, Ahmaderaghi, Baharak, Lambe, Shauna, VanSteenhouse, Harper, Lawler, Mark, Wappett, Mark, Seligmann, Bruce, Longley, Daniel B., McDade, Simon S.
Publicado 2022

Vorinostat Eliminates Multicellular Resistance of Mesothelioma 3D Spheroids via Restoration of Noxa Expression

por Barbone, Dario, Cheung, Priscilla, Battula, Sailaja, Busacca, Sara, Gray, Steven G., Longley, Daniel B., Bueno, Raphael, Sugarbaker, David J., Fennell, Dean A., Broaddus, V. Courtney
Publicado 2012

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer

por Dunne, Philip D., O'Reilly, Paul G., Coleman, Helen G., Gray, Ronan T., Longley, Daniel B., Johnston, Patrick G., Salto-Tellez, Manuel, Lawler, Mark, McArt, Darragh G.
Publicado 2016

Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer

por Ferris, Jennifer, Espona-Fiedler, Margarita, Hamilton, Claudia, Holohan, Caitriona, Crawford, Nyree, McIntyre, Alex J., Roberts, Jamie Z., Wappett, Mark, McDade, Simon S., Longley, Daniel B., Coyle, Victoria
Publicado 2020

Enhanced Antitumor Activity of the Photosensitizer meso-Tetra(N-methyl-4-pyridyl) Porphine Tetra Tosylate through Encapsulation in Antibody-Targeted Chitosan/Alginate Nanoparticles

por Abdelghany, Sharif M., Schmid, Daniela, Deacon, Jill, Jaworski, Jakub, Fay, Francois, McLaughlin, Kirsty M., Gormley, Julie A., Burrows, James F., Longley, Daniel B., Donnelly, Ryan F., Scott, Christopher J.
Publicado 2013

Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

por Fichtner, Michael, Bozkurt, Emir, Salvucci, Manuela, McCann, Christopher, McAllister, Katherine A., Halang, Luise, Düssmann, Heiko, Kinsella, Sinéad, Crawford, Nyree, Sessler, Tamas, Longley, Daniel B., Prehn, Jochen H. M.
Publicado 2020

Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists

por McCann, Christopher, Crawford, Nyree, Majkut, Joanna, Holohan, Caitriona, Armstrong, Chris W. D., Maxwell, Pamela J., Ong, Chee Wee, LaBonte, Melissa J., McDade, Simon S., Waugh, David J., Longley, Daniel B.
Publicado 2018

IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer

por Hutchinson, Ryan A, Coleman, Helen G, Gately, Kathy, Young, Vincent, Nicholson, Siobhan, Cummins, Robert, Kay, Elaine, Hynes, Sean O, Dunne, Philip D, Senevirathne, Seedevi, Hamilton, Peter W, McArt, Darragh G, Longley, Daniel B
Publicado 2017