Identification of structural aberrations in cancer by SNP array analysis

por Heinrichs, Stefan, Look, A Thomas
Publicado 2007

The MCL1-specific inhibitor S63845 acts synergistically with venetoclax/ABT-199 to induce apoptosis in T-cell acute lymphoblastic leukemia cells

por Li, Zhaodong, He, Shuning, Look, A. Thomas
Publicado 2018

From bench to patient: model systems in drug discovery

por Breyer, Matthew D., Look, A. Thomas, Cifra, Alessandra
Publicado 2015

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

por Niethammer, Philipp, Grabher, Clemens, Look, A. Thomas, Mitchison, Timothy J.
Publicado 2009

Targeting ganglioneuromas with mTOR inhibitors

por Tao, Ting, Shi, Hui, Durbin, Adam D., Look, A. Thomas
Publicado 2021

The Chromatin Remodeling Factor CHD5 Is a Transcriptional Repressor of WEE1

por Quan, Jinhua, Adelmant, Guillaume, Marto, Jarrod A., Look, A. Thomas, Yusufzai, Timur
Publicado 2014

Repression of tumor suppressor miR-451 is essential for NOTCH1-induced oncogenesis in T-ALL

por Li, Xiaoyu, Sanda, Takaomi, Look, A. Thomas, Novina, Carl D., von Boehmer, Harald
Publicado 2011

CHK1 inhibition as a strategy for targeting fanconi anemia (FA) DNA repair pathway deficient tumors

por Chen, Clark C, Kennedy, Richard D, Sidi, Samuel, Look, A Thomas, D'Andrea, Alan
Publicado 2009

ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression

por Shi, Hui, Tao, Ting, Abraham, Brian J., Durbin, Adam D., Zimmerman, Mark W., Kadoch, Cigall, Look, A. Thomas
Publicado 2020

HSP90 inhibition leads to degradation of the TYK2 kinase and apoptotic cell death in T-cell acute lymphoblastic leukemia

por Akahane, Koshi, Sanda, Takaomi, Mansour, Marc R., Radimerski, Thomas, DeAngelo, Daniel J., Weinstock, David M., Look, A. Thomas
Publicado 2015

Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb

por Grabher, Clemens, Payne, Elspeth M., Johnston, Adam B., Bolli, Niccolo, Lechman, Eric, Dick, John E., Kanki, John P., Look, A. Thomas
Publicado 2010

Human aminopeptidase N is a receptor for human coronavirus 229E

por Yeager, Curtis L., Ashmun, Richard A., Williams, Richard K., Cardellichio, Christine B., Shapiro, Linda H., Look, A. Thomas, Holmes, Kathryn V.
Publicado 1992

Loss of atrx cooperates with p53-deficiency to promote the development of sarcomas and other malignancies

por Oppel, Felix, Tao, Ting, Shi, Hui, Ross, Kenneth N., Zimmerman, Mark W., He, Shuning, Tong, Guangxiang, Aster, Jon C., Look, A. Thomas
Publicado 2019

suz12 inactivation in p53- and nf1-deficient zebrafish accelerates the onset of malignant peripheral nerve sheath tumors and expands the spectrum of tumor types

por Oppel, Felix, Ki, Dong H., Zimmerman, Mark W., Ross, Kenneth N., Tao, Ting, Shi, Hui, He, Shuning, Aster, Jon C., Look, A. Thomas
Publicado 2020

Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors

por Tao, Ting, Shi, Hui, Wang, Meng, Perez-Atayde, Antonio R., London, Wendy B., Gutierrez, Alejandro, Lemos, Bernardo, Durbin, Adam D., Look, A. Thomas
Publicado 2020

Aberrant Activation of the GIMAP Enhancer by Oncogenic Transcription Factors in T-cell Acute Lymphoblastic Leukemia

por Liau, Wei-Siang, Tan, Shi Hao, Ngoc, Phuong Cao Thi, Wang, Chelsia Qiuxia, Tergaonkar, Vinay, Feng, Hui, Gong, Zhiyuan, Osato, Motomi, Look, A. Thomas, Sanda, Takaomi
Publicado 2016

Disruption of asxl1 results in myeloproliferative neoplasms in zebrafish

por Gjini, Evisa, Jing, Chang-Bin, Nguyen, Ashley T., Reyon, Deepak, Gans, Emma, Kesarsing, Michiel, Peterson, Joshua, Pozdnyakova, Olga, Rodig, Scott J., Mansour, Marc R., Joung, Keith, Look, A. Thomas
Publicado 2019

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

por Kamizono, Shintaro, Duncan, Gordon S., Seidel, Markus G., Morimoto, Akira, Hamada, Koichi, Grosveld, Gerard, Akashi, Koichi, Lind, Evan F., Haight, Jillian P., Ohashi, Pamela S., Look, A. Thomas, Mak, Tak W.
Publicado 2009

ATM-deficient thymic lymphoma is associated with aberrant tcrd rearrangement and gene amplification

por Zha, Shan, Bassing, Craig H., Sanda, Takaomi, Brush, James W., Patel, Harin, Goff, Peter H., Murphy, Michael M., Tepsuporn, Suprawee, Gatti, Richard A., Look, A. Thomas, Alt, Frederick W.
Publicado 2010

Depletion of tet2 results in age-dependent changes in DNA methylation and gene expression in a zebrafish model of myelodysplastic syndrome

por Neelamraju, Yaseswini, Gjini, Evisa, Chhangawala, Sagar, Fan, Hao, He, Shuning, Jing, Chang-Bin, Nguyen, Ashley T., Prajapati, Subhash, Sheridan, Caroline, Houvras, Yariv, Melnick, Ari, Look, A. Thomas, Garrett-Bakelman, Francine E.
Publicado 2023