Hierarchical optimization for the efficient parametrization of ODE models

por Loos, Carolin, Krause, Sabrina, Hasenauer, Jan
Publicado 2018

Comparison of null models for combination drug therapy reveals Hand model as biochemically most plausible

por Sinzger, Mark, Vanhoefer, Jakob, Loos, Carolin, Hasenauer, Jan
Publicado 2019

Benchmark problems for dynamic modeling of intracellular processes

por Hass, Helge, Loos, Carolin, Raimúndez-Álvarez, Elba, Timmer, Jens, Hasenauer, Jan, Kreutz, Clemens
Publicado 2019

PESTO: Parameter EStimation TOolbox

por Stapor, Paul, Weindl, Daniel, Ballnus, Benjamin, Hug, Sabine, Loos, Carolin, Fiedler, Anna, Krause, Sabrina, Hroß, Sabrina, Fröhlich, Fabian, Hasenauer, Jan
Publicado 2018

Evolution of Early SARS-CoV-2 and Cross-Coronavirus Immunity

por Loos, Carolin, Atyeo, Caroline, Fischinger, Stephanie, Burke, John, Slein, Matthew D., Streeck, Hendrik, Lauffenburger, Douglas, Ryan, Edward T., Charles, Richelle C., Alter, Galit
Publicado 2020

Functional Compartmentalization of Antibodies in the Central Nervous System During Chronic HIV Infection

por Spatola, Marianna, Loos, Carolin, Cizmeci, Deniz, Webb, Nicholas, Gorman, Matthew J, Rossignol, Evan, Shin, Sally, Yuan, Dansu, Fontana, Laura, Mukerji, Shibani S, Lauffenburger, Douglas A, Gabuzda, Dana, Alter, Galit
Publicado 2022

Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design

por Loos, Carolin, Coccia, Margherita, Didierlaurent, Arnaud M., Essaghir, Ahmed, Fallon, Jonathan K., Lauffenburger, Douglas, Luedemann, Corinne, Michell, Ashlin, van der Most, Robbert, Zhu, Alex Lee, Alter, Galit, Burny, Wivine
Publicado 2023

Viral Rebound Kinetics Correlate with Distinct HIV Antibody Features

por Bartsch, Yannic C., Loos, Carolin, Rossignol, Evan, Fajnzylber, Jesse M., Yuan, Dansu, Avihingsanon, Anchalee, Ubolyam, Sasiwimol, Jupimai, Thidarat, Hirschel, Bernard, Ananworanich, Jintanat, Lauffenburger, Douglas A., Li, Jonathan Z., Alter, Galit, Julg, Boris
Publicado 2021

Functional Antibodies in COVID-19 Convalescent Plasma

por Herman, Jonathan D., Wang, Chuangqi, Loos, Carolin, Yoon, Hyunah, Rivera, Johanna, Dieterle, M. Eugenia, Haslwanter, Denise, Jangra, Rohit K., Bortz, Robert H., Bar, Katharine J., Julg, Boris, Chandran, Kartik, Lauffenburger, Douglas, Pirofski, Liise-anne, Alter, Galit
Publicado 2021

Functional convalescent plasma antibodies and pre-infusion titers shape the early severe COVID-19 immune response

por Herman, Jonathan D., Wang, Chuangqi, Loos, Carolin, Yoon, Hyunah, Rivera, Johanna, Eugenia Dieterle, M., Haslwanter, Denise, Jangra, Rohit K., Bortz, Robert H., Bar, Katharine J., Julg, Boris, Chandran, Kartik, Lauffenburger, Douglas, Pirofski, Liise-anne, Alter, Galit
Publicado 2021

Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality

por Zohar, Tomer, Loos, Carolin, Fischinger, Stephanie, Atyeo, Caroline, Wang, Chuangqi, Slein, Matthew D., Burke, John, Yu, Jingyou, Feldman, Jared, Hauser, Blake Marie, Caradonna, Tim, Schmidt, Aaron G., Cai, Yongfei, Streeck, Hendrik, Ryan, Edward T., Barouch, Dan H., Charles, Richelle C., Lauffenburger, Douglas A., Alter, Galit
Publicado 2020

T cell and antibody functional correlates of severe COVID-19

por Yu, Krystle K.Q., Fischinger, Stephanie, Smith, Malisa T., Atyeo, Caroline, Cizmeci, Deniz, Wolf, Caitlin R., Layton, Erik D., Logue, Jennifer K., Aguilar, Melissa S., Shuey, Kiel, Loos, Carolin, Yu, Jingyou, Franko, Nicholas, Choi, Robert Y., Wald, Anna, Barouch, Dan H., Koelle, David M., Lauffenburger, Douglas, Chu, Helen Y., Alter, Galit, Seshadri, Chetan
Publicado 2020

Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2

por Yu, Krystle K.Q., Fischinger, Stephanie, Smith, Malisa T., Atyeo, Caroline, Cizmeci, Deniz, Wolf, Caitlin R., Layton, Erik D., Logue, Jennifer K., Aguilar, Melissa S., Shuey, Kiel, Loos, Carolin, Yu, Jingyou, Franko, Nicholas, Choi, Robert Y., Wald, Anna, Barouch, Dan H., Koelle, David M., Lauffenburger, Douglas, Chu, Helen Y., Alter, Galit, Seshadri, Chetan
Publicado 2021

SARS-CoV-2-specific ELISA development

por Roy, Vicky, Fischinger, Stephanie, Atyeo, Caroline, Slein, Matthew, Loos, Carolin, Balazs, Alejandro, Luedemann, Corinne, Astudillo, Michael Gerino, Yang, Diane, Wesemann, Duane R., Charles, Richelle, Lafrate, A. John, Feldman, Jared, Hauser, Blake, Caradonna, Tim, Miller, Tyler E., Murali, Mandakolathur R., Baden, Lindsey, Nilles, Eric, Ryan, Edward, Lauffenburger, Douglas, Beltran, Wilfredo Garcia, Alter, Galit
Publicado 2020

Distinct Early Serological Signatures Track with SARS-CoV-2 Survival

por Atyeo, Caroline, Fischinger, Stephanie, Zohar, Tomer, Slein, Matthew D., Burke, John, Loos, Carolin, McCulloch, Denise J., Newman, Kira L., Wolf, Caitlin, Yu, Jingyou, Shuey, Kiel, Feldman, Jared, Hauser, Blake Marie, Caradonna, Tim, Schmidt, Aaron G., Suscovich, Todd J., Linde, Caitlyn, Cai, Yongfei, Barouch, Dan, Ryan, Edward T., Charles, Richelle C., Lauffenburger, Douglas, Chu, Helen, Alter, Galit
Publicado 2020

PEtab—Interoperable specification of parameter estimation problems in systems biology

por Schmiester, Leonard, Schälte, Yannik, Bergmann, Frank T., Camba, Tacio, Dudkin, Erika, Egert, Janine, Fröhlich, Fabian, Fuhrmann, Lara, Hauber, Adrian L., Kemmer, Svenja, Lakrisenko, Polina, Loos, Carolin, Merkt, Simon, Müller, Wolfgang, Pathirana, Dilan, Raimúndez, Elba, Refisch, Lukas, Rosenblatt, Marcus, Stapor, Paul L., Städter, Philipp, Wang, Dantong, Wieland, Franz-Georg, Banga, Julio R., Timmer, Jens, Villaverde, Alejandro F., Sahle, Sven, Kreutz, Clemens, Hasenauer, Jan, Weindl, Daniel
Publicado 2021

Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01(B) malaria vaccine

por Nielsen, Carolyn M., Barrett, Jordan R., Davis, Christine, Fallon, Jonathan K., Goh, Cyndi, Michell, Ashlin R., Griffin, Catherine, Kwok, Andrew, Loos, Carolin, Darko, Samuel, Laboune, Farida, Tekman, Mehmet, Diouf, Ababacar, Miura, Kazutoyo, Francica, Joseph R., Ransier, Amy, Long, Carole A., Silk, Sarah E., Payne, Ruth O., Minassian, Angela M., Lauffenburger, Douglas A., Seder, Robert A., Douek, Daniel C., Alter, Galit, Draper, Simon J.
Publicado 2023

Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination

por Alter, Galit, Gorman, Matthew, Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex, Atyeo, Caroline, Pullen, Krista, Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yuan, Dansu, Bowman, Kathryn, Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa, Logue, James, Frieman, Matthew, Montefiori, David, Schendel, Sharon, Saphire, Erica Ollmann, Lauffenburger, Douglas, Greene, Ann, Portnoff, Alyse, Massare, Michael, Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Mann, Colin, Amanat, Fatima, Krammer, Florian
Publicado 2021

Compromised SARS-CoV-2-specific placental antibody transfer

por Atyeo, Caroline, Pullen, Krista M., Bordt, Evan A., Fischinger, Stephanie, Burke, John, Michell, Ashlin, Slein, Matthew D., Loos, Carolin, Shook, Lydia L., Boatin, Adeline A., Yockey, Laura J., Pepin, David, Meinsohn, Marie-Charlotte, Nguyen, Ngoc Minh Phuong, Chauvin, Maeva, Roberts, Drucilla, Goldfarb, Ilona T., Matute, Juan D., James, Kaitlyn E., Yonker, Lael M., Bebell, Lisa M., Kaimal, Anjali J., Gray, Kathryn J., Lauffenburger, Douglas, Edlow, Andrea G., Alter, Galit
Publicado 2021

Correlates of Protection Against SARS-CoV-2 in Rhesus Macaques

por McMahan, Katherine, Yu, Jingyou, Mercado, Noe B., Loos, Carolin, Tostanoski, Lisa H., Chandrashekar, Abishek, Liu, Jinyan, Peter, Lauren, Atyeo, Caroline, Zhu, Alex, Bondzie, Esther A., Dagotto, Gabriel, Gebre, Makda S., Jacob-Dolan, Catherine, Li, Zhenfeng, Nampanya, Felix, Patel, Shivani, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Yalley-Ogunro, Jake, Cabus, Mehtap, Brown, Renita, Cook, Anthony, Teow, Elyse, Andersen, Hanne, Lewis, Mark G., Lauffenburger, Douglas A., Alter, Galit, Barouch, Dan H.
Publicado 2020