Interaction Effect between Physical Activity and the BDNF Val66Met Polymorphism on Depression in Women from the PISMA-ep Study

por Zarza-Rebollo, Juan Antonio, Molina, Esther, López-Isac, Elena, Pérez-Gutiérrez, Ana M., Gutiérrez, Blanca, Cervilla, Jorge A., Rivera, Margarita
Publicado 2022

No evidence that genetic predictors of susceptibility predict changes in core outcomes in JIA

por Yarwood, Annie, Shoop-Worrall, Stephanie, López-Isac, Elena, Smith, Samantha Louise, Morris, Andrew P, Bowes, John David, Tordoff, Melissa, Hyrich, Kimme L, Thomson, Wendy, Eyre, Stephen
Publicado 2022

Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci

por Li, Tianlu, Ortiz-Fernández, Lourdes, Andrés-León, Eduardo, Ciudad, Laura, Javierre, Biola M., López-Isac, Elena, Guillén-Del-Castillo, Alfredo, Simeón-Aznar, Carmen Pilar, Ballestar, Esteban, Martin, Javier
Publicado 2020

A cross-disease meta-GWAS identifies four new susceptibility loci shared between systemic sclerosis and Crohn’s disease

por González-Serna, David, Ochoa, Eguzkine, López-Isac, Elena, Julià, Antonio, Degenhardt, Frauke, Ortego-Centeno, Norberto, Radstake, Timothy R. D. J., Franke, Andre, Marsal, Sara, Mayes, Maureen D., Martín, Javier, Márquez, Ana
Publicado 2020

Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms

por López-Isac, Elena, Smith, Samantha L, Marion, Miranda C, Wood, Abigail, Sudman, Marc, Yarwood, Annie, Shi, Chenfu, Gaddi, Vasanthi Priyadarshini, Martin, Paul, Prahalad, Sampath, Eyre, Stephen, Orozco, Gisela, Morris, Andrew P, Langefeld, Carl D, Thompson, Susan D, Thomson, Wendy, Bowes, John
Publicado 2021

Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk

por Pouget, Jennie G, Han, Buhm, Wu, Yang, Mignot, Emmanuel, Ollila, Hanna M, Barker, Jonathan, Spain, Sarah, Dand, Nick, Trembath, Richard, Martin, Javier, Mayes, Maureen D, Bossini-Castillo, Lara, López-Isac, Elena, Jin, Ying, Santorico, Stephanie A, Spritz, Richard A, Hakonarson, Hakon, Polychronakos, Constantin, Raychaudhuri, Soumya, Knight, Jo
Publicado 2019

Body mass index interacts with a genetic-risk score for depression increasing the risk of the disease in high-susceptibility individuals

por Anguita-Ruiz, Augusto, Zarza-Rebollo, Juan Antonio, Pérez-Gutiérrez, Ana M, Molina, Esther, Gutiérrez, Blanca, Bellón, Juan Ángel, Moreno-Peral, Patricia, Conejo-Cerón, Sonia, Aiarzagüena, Jose María, Ballesta-Rodríguez, M Isabel, Fernández, Anna, Fernández-Alonso, Carmen, Martín-Pérez, Carlos, Montón-Franco, Carmen, Rodríguez-Bayón, Antonina, Torres-Martos, Álvaro, López-Isac, Elena, Cervilla, Jorge, Rivera, Margarita
Publicado 2022

Comprehensive analysis of the major histocompatibility complex in systemic sclerosis identifies differential HLA associations by clinical and serological subtypes

por Acosta-Herrera, Marialbert, Kerick, Martin, Lopéz-Isac, Elena, Assassi, Shervin, Beretta, Lorenzo, Simeón-Aznar, Carmen Pilar, Ortego-Centeno, Norberto, Proudman, Susanna M, Hunzelmann, Nicolas, Moroncini, Gianluca, de Vries-Bouwstra, Jeska K, Orozco, Gisela, Barton, Anne, Herrick, Ariane L, Terao, Chikashi, Allanore, Yannick, Brown, Matthew A, Radstake, Timothy RDJ, Fonseca, Carmen, Denton, Christopher P, Mayes, Maureen D, Martin, Javier
Publicado 2021

The Effect of Body Fat Distribution on Systemic Sclerosis

por Villanueva-Martin, Gonzalo, Acosta-Herrera, Marialbert, Kerick, Martin, López-Isac, Elena, Simeón, Carmen P., Callejas, José L., Assassi, Shervin, Beretta, Lorenzo, SSc Group, International, (ASIG), Australian Scleroderma Interest Group, Allanore, Yannick, Proudman, Susanna M., Nikpour, Mandana, Fonseca, Carmen, Denton, Christopher P., Radstake, Timothy R. D. J., Mayes, Maureen D., Jiang, Xia, Martin, Javier, Bossini-Castillo, Lara
Publicado 2022

A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility

por López-Isac, Elena, Bossini-Castillo, Lara, Simeon, Carmen P, Egurbide, María Victoria, Alegre-Sancho, Juan José, Callejas, Jose Luis, Roman-Ivorra, José Andrés, Freire, Mayka, Beretta, Lorenzo, Santaniello, Alessandro, Airó, Paolo, Lunardi, Claudio, Hunzelmann, Nicolas, Riemekasten, Gabriela, Witte, Torsten, Kreuter, Alexander, Distler, Jörg H W, Schuerwegh, Annemie J, Vonk, Madelon C, Voskuyl, Alexandre E, Shiels, Paul G, van Laar, Jacob M, Fonseca, Carmen, Denton, Christopher, Herrick, Ariane, Worthington, Jane, Assassi, Shervin, Koeleman, Bobby P, Mayes, Maureen D, Radstake, Timothy RDJ, Martin, Javier
Publicado 2014

Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations

por Gorlova, Olga Y., Li, Yafang, Gorlov, Ivan, Ying, Jun, Chen, Wei V., Assassi, Shervin, Reveille, John D., Arnett, Frank C., Zhou, Xiaodong, Bossini-Castillo, Lara, Lopez-Isac, Elena, Acosta-Herrera, Marialbert, Gregersen, Peter K., Lee, Annette T., Steen, Virginia D., Fessler, Barri J., Khanna, Dinesh, Schiopu, Elena, Silver, Richard M., Molitor, Jerry A., Furst, Daniel E., Kafaja, Suzanne, Simms, Robert W., Lafyatis, Robert A., Carreira, Patricia, Simeon, Carmen Pilar, Castellvi, Ivan, Beltran, Emma, Ortego, Norberto, Amos, Christopher I., Martin, Javier, Mayes, Maureen D.
Publicado 2018

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

por López-Isac, Elena, Acosta-Herrera, Marialbert, Kerick, Martin, Assassi, Shervin, Satpathy, Ansuman T., Granja, Jeffrey, Mumbach, Maxwell R., Beretta, Lorenzo, Simeón, Carmen P., Carreira, Patricia, Ortego-Centeno, Norberto, Castellvi, Ivan, Bossini-Castillo, Lara, Carmona, F. David, Orozco, Gisela, Hunzelmann, Nicolas, Distler, Jörg H. W., Franke, Andre, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, de Vries-Bouwstra, Jeska, Wijmenga, Cisca, Koeleman, Bobby P. C., Nordin, Annika, Padyukov, Leonid, Hoffmann-Vold, Anna-Maria, Lie, Benedicte, Proudman, Susanna, Stevens, Wendy, Nikpour, Mandana, Vyse, Timothy, Herrick, Ariane L., Worthington, Jane, Denton, Christopher P., Allanore, Yannick, Brown, Matthew A., Radstake, Timothy R. D. J., Fonseca, Carmen, Chang, Howard Y., Mayes, Maureen D., Martin, Javier
Publicado 2019