ASPP2κ Is Expressed In Human Colorectal Carcinoma And Promotes Chemotherapy Resistance And Tumorigenesis

por Rieger, Ingmar, Tsintari, Vasileia, Overkamp, Mathis, Fend, Falko, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.
Publicado 2021

Alternative splicing of Apoptosis Stimulating Protein of TP53-2 (ASPP2) results in an oncogenic isoform promoting migration and therapy resistance in soft tissue sarcoma (STS)

por Tsintari, Vasileia, Walter, Bianca, Fend, Falko, Overkamp, Mathis, Rothermundt, Christian, Lopez, Charles D., Schittenhelm, Marcus M., Kampa-Schittenhelm, Kerstin M.
Publicado 2022

Attenuated Expression of Apoptosis Stimulating Protein of p53-2 (ASPP2) in Human Acute Leukemia Is Associated with Therapy Failure

por Schittenhelm, Marcus M., Illing, Barbara, Ahmut, Figen, Rasp, Katharina Henriette, Blumenstock, Gunnar, Döhner, Konstanze, Lopez, Charles D., Kampa-Schittenhelm, Kerstin M.
Publicado 2013

Effect of Time to Surgery of Colorectal Liver Metastases on Survival

por Chen, Emerson Y., Mayo, Skye C., Sutton, Thomas, Kearney, Matthew R., Kardosh, Adel, Vaccaro, Gina M., Billingsley, Kevin G., Lopez, Charles D.
Publicado 2020

Geographic Disparities in Referral Rates and Oncologic Outcomes of Intrahepatic Cholangiocarcinoma: A Population-Based Study

por Sutton, Thomas L., Walker, Brett S., Nabavizadeh, Nima, Grossberg, Aaron, Thomas, Charles R., Lopez, Charles D., Kardosh, Adel, Chen, Emerson Y., Sheppard, Brett C., Mayo, Skye C.
Publicado 2021

Therapy Resistant Gastroenteropancreatic Neuroendocrine Tumors

por McClellan, Kristen, Chen, Emerson Y., Kardosh, Adel, Lopez, Charles D., Del Rivero, Jaydira, Mallak, Nadine, Rocha, Flavio G., Koethe, Yilun, Pommier, Rodney, Mittra, Erik, Pegna, Guillaume J.
Publicado 2022

Randomized phase II study of the Bruton tyrosine kinase inhibitor acalabrutinib, alone or with pembrolizumab in patients with advanced pancreatic cancer

por Overman, Michael, Javle, Milind, Davis, Richard E, Vats, Pankaj, Kumar-Sinha, Chandan, Xiao, Lianchun, Mettu, Niharika B, Parra, Edwin R, Benson, Al B, Lopez, Charles D, Munugalavadla, Veerendra, Patel, Priti, Tao, Lin, Neelapu, Sattva, Maitra, Anirban
Publicado 2020

Randomized Phase III Study of FOLFOX Alone or With Pegilodecakin as Second-Line Therapy in Patients With Metastatic Pancreatic Cancer That Progressed After Gemcitabine (SEQUOIA)

por Hecht, J. Randolph, Lonardi, Sara, Bendell, Johanna, Sim, Hao-Wen, Macarulla, Teresa, Lopez, Charles D., Van Cutsem, Eric, Muñoz Martin, Andres J., Park, Joon Oh, Greil, Richard, Wang, Hong, Hozak, Rebecca R., Gueorguieva, Ivelina, Lin, Yong, Rao, Sujata, Ryoo, Baek-Yeol
Publicado 2021

Phase 2 study of preoperative chemotherapy with nab‐paclitaxel and gemcitabine followed by chemoradiation for borderline resectable or node‐positive pancreatic ductal adenocarcinom...

por Chen, Emerson Y., Kardosh, Adel, Nabavizadeh, Nima, Foster, Bryan, Mayo, Skye C., Billingsley, Kevin G., Gilbert, Erin W., Lanciault, Christian, Grossberg, Aaron, Bensch, Kenneth G., Maynard, Erin, Anderson, Eric C., Sheppard, Brett C., Thomas, Charles R., Lopez, Charles D., Vaccaro, Gina M.
Publicado 2023

Efficacy and safety of maintenance therapy with pamiparib versus placebo for advanced gastric cancer responding to first‐line platinum‐based chemotherapy: Phase 2 study results

por Ciardiello, Fortunato, Bang, Yung‐Jue, Cervantes, Andrés, Dvorkin, Mikhail, Lopez, Charles D., Metges, Jean‐Philippe, Sánchez Ruiz, Antonio, Calvo, Mariona, Strickland, Andrew H., Kannourakis, George, Muro, Kei, Kawakami, Hisato, Wei, Jia, Borg, Christophe, Zhu, Zhaoyin, Gupta, Neal, Pelham, Robert J., Shen, Lin
Publicado 2023

Tumor-Infiltrating Leukocyte Phenotypes Distinguish Outcomes in Related Patients With Pancreatic Adenocarcinoma

por Link, Jason M., Liudahl, Shannon M., Betts, Courtney B., Sivagnanam, Shamilene, Leis, Kenna R., McDonnell, Mary, Pelz, Carl R., Johnson, Brett, Hamman, Kelly J., Keith, Dove, Sampson, Jone E., Morgan, Terry K., Lopez, Charles D., Coussens, Lisa M., Sears, Rosalie C.
Publicado 2021

Implementing a comprehensive translational oncology platform: from molecular testing to actionability

por Mitri, Zahi I., Parmar, Swapnil, Johnson, Brett, Kolodzie, Annette, Keck, Jamie M., Morris, Max, Guimaraes, Alexander R., Beckett, Brooke R., Borate, Uma, Lopez, Charles D., Kemmer, Kathleen A., Alumkal, Joshi J., Beer, Tomasz M., Corless, Christopher L., Mills, Gordon B., Gray, Joe W., Bergan, Raymond C.
Publicado 2018

Atezolizumab Plus PEGPH20 Versus Chemotherapy in Advanced Pancreatic Ductal Adenocarcinoma and Gastric Cancer: MORPHEUS Phase Ib/II Umbrella Randomized Study Platform

por Ko, Andrew H, Kim, Kyu-Pyo, Siveke, Jens T, Lopez, Charles D, Lacy, Jill, O’Reilly, Eileen M, Macarulla, Teresa, Manji, Gulam A, Lee, Jeeyun, Ajani, Jaffer, Alsina Maqueda, Maria, Rha, Sun-Young, Lau, Janet, Al-Sakaff, Nedal, Allen, Simon, Lu, Danny, Shemesh, Colby S, Gan, Xinxin, Cha, Edward, Oh, Do-Youn
Publicado 2023

Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions

por Zarour, Luai R., Anand, Sudarshan, Billingsley, Kevin G., Bisson, William H., Cercek, Andrea, Clarke, Michael F., Coussens, Lisa M., Gast, Charles E., Geltzeiler, Cristina B., Hansen, Lissi, Kelley, Katherine A., Lopez, Charles D., Rana, Shushan R., Ruhl, Rebecca, Tsikitis, V. Liana, Vaccaro, Gina M., Wong, Melissa H., Mayo, Skye C.
Publicado 2017

Neoadjuvant Therapy Is Associated with Improved Chemotherapy Delivery and Overall Survival Compared to Upfront Resection in Pancreatic Cancer without Increasing Perioperative Compl...

por Deig, Christopher Ryan, Sutton, Thomas Lee, Beneville, Blake, Trone, Kristin, Stratton, Amanda, Gunesch, Ali N., Liu, Amy Ivy, Alrohaibani, Alaaeddin, Mohebnasab, Maedeh, Bassale, Solange, Grossblatt-Wait, Alison, Keith, Dove, Attia, Fouad, Gilbert, Erin W., Lopez, Charles D., Kardosh, Adel, Chen, Emerson Y., Bensch, Kenneth G., Nabavizadeh, Nima, Thomas, Charles R., Mayo, Skye C., Sheppard, Brett C., Grossberg, Aaron
Publicado 2022

Modulation of myeloid and T cells in vivo by Bruton’s tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma

por Sinha, Meenal, Betts, Courtney, Zhang, Li, Griffith, Madeline J, Solman, Isabelle, Chen, Brandon, Liu, Eric, Tamaki, Whitney, Stultz, Jacob, Marquez, Jaqueline, Sivagnanam, Shamilene, Cheung, Alexander, Pener, Denise, Fahlman, Anne, Taber, Erin, Lerner, Kimberly, Crocker, Matthew, Todd, Kendra, Rajagopalan, Brindha, Ware, Clarisha, Bridge, Mark, Vo, Johnson, Dragomanovich, Hannah, Sudduth-Klinger, Julie, Vaccaro, Gina, Lopez, Charles D, Tempero, Margaret, Coussens, Lisa M, Fong, Lawrence
Publicado 2023

Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival

por Gast, Charles E., Silk, Alain D., Zarour, Luai, Riegler, Lara, Burkhart, Joshua G., Gustafson, Kyle T., Parappilly, Michael S., Roh-Johnson, Minna, Goodman, James R., Olson, Brennan, Schmidt, Mark, Swain, John R., Davies, Paige S., Shasthri, Vidya, Iizuka, Shinji, Flynn, Patrick, Watson, Spencer, Korkola, James, Courtneidge, Sara A., Fischer, Jared M., Jaboin, Jerry, Billingsley, Kevin G., Lopez, Charles D., Burchard, Julja, Gray, Joe, Coussens, Lisa M., Sheppard, Brett C., Wong, Melissa H.
Publicado 2018

Adjuvant nab-Paclitaxel + Gemcitabine in Resected Pancreatic Ductal Adenocarcinoma: Results From a Randomized, Open-Label, Phase III Trial

por Tempero, Margaret A., Pelzer, Uwe, O'Reilly, Eileen M., Winter, Jordan, Oh, Do-Youn, Li, Chung-Pin, Tortora, Giampaolo, Chang, Heung-Moon, Lopez, Charles D., Bekaii-Saab, Tanios, Ko, Andrew H., Santoro, Armando, Park, Joon Oh, Noel, Marcus S., Frassineti, Giovanni Luca, Shan, Yan-Shen, Dean, Andrew, Riess, Hanno, Van Cutsem, Eric, Berlin, Jordan, Philip, Philip, Moore, Malcolm, Goldstein, David, Tabernero, Josep, Li, Mingyu, Ferrara, Stefano, Le Bruchec, Yvan, Zhang, George, Lu, Brian, Biankin, Andrew V., Reni, Michele
Publicado 2023

Relevance of circulating hybrid cells as a non-invasive biomarker for myriad solid tumors

por Dietz, Matthew S., Sutton, Thomas L., Walker, Brett S., Gast, Charles E., Zarour, Luai, Sengupta, Sidharth K., Swain, John R., Eng, Jennifer, Parappilly, Michael, Limbach, Kristen, Sattler, Ariana, Burlingame, Erik, Chin, Yuki, Gower, Austin, Mira, Jose L. Montoya, Sapre, Ajay, Chiu, Yu-Jui, Clayburgh, Daniel R., Pommier, SuEllen J., Cetnar, Jeremy P., Fischer, Jared M., Jaboin, Jerry J., Pommier, Rodney F., Sheppard, Brett C., Tsikitis, V. Liana, Skalet, Alison H., Mayo, Skye C., Lopez, Charles D., Gray, Joe W., Mills, Gordon B., Mitri, Zahi, Chang, Young Hwan, Chin, Koei, Wong, Melissa H.
Publicado 2021