Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma

por Delgado, Teresa Cardoso, Lopitz-Otsoa, Fernando, Martínez-Chantar, María Luz
Publicado 2019

Strategies to Identify Recognition Signals and Targets of SUMOylation

por Da Silva-Ferrada, Elisa, Lopitz-Otsoa, Fernando, Lang, Valérie, Rodríguez, Manuel S., Matthiesen, Rune
Publicado 2012

One Carbon Metabolism and S-Adenosylmethionine in Non-Alcoholic Fatty Liver Disease Pathogenesis and Subtypes

por Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Millet, Oscar, Alonso, Cristina, Lu, Shelly C., Mato, José M.
Publicado 2022

Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity

por Aillet, Fabienne, Lopitz-Otsoa, Fernando, Egaña, Isabel, Hjerpe, Roland, Fraser, Paul, Hay, Ron T., Rodriguez, Manuel S., Lang, Valérie
Publicado 2012

Scavenger Receptors Mediate the Role of SUMO and Ftz-f1 in Drosophila Steroidogenesis

por Talamillo, Ana, Herboso, Leire, Pirone, Lucia, Pérez, Coralia, González, Monika, Sánchez, Jonatan, Mayor, Ugo, Lopitz-Otsoa, Fernando, Rodriguez, Manuel S., Sutherland, James D., Barrio, Rosa
Publicado 2013

Evolution of SUMO Function and Chain Formation in Insects

por Ureña, Enric, Pirone, Lucia, Chafino, Silvia, Pérez, Coralia, Sutherland, James D., Lang, Valérie, Rodriguez, Manuel S., Lopitz-Otsoa, Fernando, Blanco, Francisco J., Barrio, Rosa, Martín, David
Publicado 2016

Ubiquitin-Like Post-Translational Modifications (Ubl-PTMs): Small Peptides with Huge Impact in Liver Fibrosis

por Lachiondo-Ortega, Sofia, Mercado-Gómez, Maria, Serrano-Maciá, Marina, Lopitz-Otsoa, Fernando, Salas-Villalobos, Tanya B, Varela-Rey, Marta, Delgado, Teresa C., Martínez-Chantar, María Luz
Publicado 2019

Therapeutic Targeting of Fumaryl Acetoacetate Hydrolase in Hereditary Tyrosinemia Type I

por Gil-Martínez, Jon, Macias, Iratxe, Unione, Luca, Bernardo-Seisdedos, Ganeko, Lopitz-Otsoa, Fernando, Fernandez-Ramos, David, Lain, Ana, Sanz-Parra, Arantza, Mato, José M, Millet, Oscar
Publicado 2021

Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis

por Bhattacharya, Dipankar, Basta, Brittany, Mato, Jose M., Craig, Amanda, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Tsvirkun, Darya, Hayardeny, Liat, Chandar, Vasuretha, Schwartz, Robert E., Villanueva, Augusto, Friedman, Scott L.
Publicado 2021

Analysis of SUMOylated proteins using SUMO-traps

por Da Silva-Ferrada, Elisa, Xolalpa, Wendy, Lang, Valérie, Aillet, Fabienne, Martin-Ruiz, Itziar, de la Cruz-Herrera, Carlos F., Lopitz-Otsoa, Fernando, Carracedo, Arkaitz, Goldenberg, Seth J., Rivas, Carmen, England, Patrick, Rodríguez, Manuel S.
Publicado 2013

Metabolic Landscape of the Mouse Liver by Quantitative (31)P Nuclear Magnetic Resonance Analysis of the Phosphorome

por Bernardo‐Seisdedos, Ganeko, Bilbao, Jon, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando, Gutierrez de Juan, Virginia, Bizkarguenaga, Maider, Mateos, Borja, Fondevila, Marcos F., Abril‐Fornaguera, Jordi, Diercks, Tammo, Lu, Shelly C., Nogueiras, Rubén, Mato, José M., Millet, Oscar
Publicado 2021

Hyperphosphorylation of hepatic proteome characterizes nonalcoholic fatty liver disease in S-adenosylmethionine deficiency

por Robinson, Aaron E., Binek, Aleksandra, Ramani, Komal, Sundararaman, Niveda, Barbier-Torres, Lucía, Murray, Ben, Venkatraman, Vidya, Kreimer, Simion, Ardle, Angela Mc, Noureddin, Mazen, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Gutiérrez de Juan, Virginia, Millet, Oscar, Mato, José M., Lu, Shelly C., Van Eyk, Jennifer E.
Publicado 2023

SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

por Bruzzone, Chiara, Bizkarguenaga, Maider, Gil-Redondo, Rubén, Diercks, Tammo, Arana, Eunate, García de Vicuña, Aitor, Seco, Marisa, Bosch, Alexandre, Palazón, Asís, San Juan, Itxaso, Laín, Ana, Gil-Martínez, Jon, Bernardo-Seisdedos, Ganeko, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Embade, Nieves, Lu, Shelly, Mato, José M., Millet, Oscar
Publicado 2020

SerpinB3 Differently Up-Regulates Hypoxia Inducible Factors-1α and -2α in Hepatocellular Carcinoma: Mechanisms Revealing Novel Potential Therapeutic Targets

por Cannito, Stefania, Foglia, Beatrice, Villano, Gianmarco, Turato, Cristian, C Delgado, Teresa, Morello, Elisabetta, Pin, Fabrizio, Novo, Erica, Napione, Lucia, Quarta, Santina, Ruvoletto, Mariagrazia, Fasolato, Silvano, Zanus, Giacomo, Colombatto, Sebastiano, Lopitz-Otsoa, Fernando, Fernández-Ramos, David, Bussolino, Federico, Sutti, Salvatore, Albano, Emanuele, Martínez-Chantar, Maria Luz, Pontisso, Patrizia, Parola, Maurizio
Publicado 2019

Arachidyl amido cholanoic acid improves liver glucose and lipid homeostasis in nonalcoholic steatohepatitis via AMPK and mTOR regulation

por Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Delacruz-Villar, Laura, Bilbao, Jon, Pagano, Martina, Mosca, Laura, Bizkarguenaga, Maider, Serrano-Macia, Marina, Azkargorta, Mikel, Iruarrizaga-Lejarreta, Marta, Sot, Jesús, Tsvirkun, Darya, van Liempd, Sebastiaan Martijn, Goni, Felix M, Alonso, Cristina, Martínez-Chantar, María Luz, Elortza, Felix, Hayardeny, Liat, Lu, Shelly C, Mato, José M
Publicado 2020

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

por Barbier-Torres, Lucía, Murray, Ben, Yang, Jin Won, Wang, Jiaohong, Matsuda, Michitaka, Robinson, Aaron, Binek, Aleksandra, Fan, Wei, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Luque-Urbano, Maria, Millet, Oscar, Mavila, Nirmala, Peng, Hui, Ramani, Komal, Gottlieb, Roberta, Sun, Zhaoli, Liangpunsakul, Suthat, Seki, Ekihiro, Van Eyk, Jennifer E., Mato, Jose M., Lu, Shelly C.
Publicado 2022

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

por Barbier-Torres, Lucía, Delgado, Teresa C., García-Rodríguez, Juan L., Zubiete-Franco, Imanol, Fernández-Ramos, David, Buqué, Xabier, Cano, Ainara, Juan, Virginia Gutiérrez-de, Fernández-Domínguez, Itziar, Lopitz-Otsoa, Fernando, Fernández-Tussy, Pablo, Boix, Loreto, Bruix, Jordi, Villa, Erica, Castro, Azucena, Lu, Shelly C., Aspichueta, Patricia, Xirodimas, Dimitris, Varela-Rey, Marta, Mato, José M., Beraza, Naiara, Martínez-Chantar, María L.
Publicado 2014

A morphological method for ammonia detection in liver

por Gutiérrez-de-Juan, Virginia, López de Davalillo, Sergio, Fernández-Ramos, David, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Fernández-Tussy, Pablo, Simon, Jorge, Lopitz-Otsoa, Fernando, de las Heras, Javier, Iruzubieta, Paula, Arias-Loste, María Teresa, Villa, Erica, Crespo, Javier, Andrade, Raúl, Lucena, M. Isabel, Varela-Rey, Marta, Lu, Shelly C., Mato, José M., Delgado, Teresa Cardoso, Martínez-Chantar, María-Luz
Publicado 2017

Hepatocyte-specific O-GlcNAc transferase downregulation ameliorates nonalcoholic steatohepatitis by improving mitochondrial function

por Gonzalez-Rellan, Maria J., Parracho, Tamara, Heras, Violeta, Rodriguez, Amaia, Fondevila, Marcos F., Novoa, Eva, Lima, Natalia, Varela-Rey, Marta, Senra, Ana, Chantada-Vazquez, Maria D.P., Ameneiro, Cristina, Bernardo, Ganeko, Fernandez-Ramos, David, Lopitz-Otsoa, Fernando, Bilbao, Jon, Guallar, Diana, Fidalgo, Miguel, Bravo, Susana, Dieguez, Carlos, Martinez-Chantar, Maria L., Millet, Oscar, Mato, Jose M., Schwaninger, Markus, Prevot, Vincent, Crespo, Javier, Frühbeck, Gema, Iruzubieta, Paula, Nogueiras, Ruben
Publicado 2023

MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

por Fernández-Ramos, David, Fernández-Tussy, Pablo, Lopitz-Otsoa, Fernando, Gutiérrez-de-Juan, Virginia, Navasa, Nicolás, Barbier-Torres, Lucía, Zubiete-Franco, Imanol, Simón, Jorge, Fernández, Agustín F., Arbelaiz, Ander, Aransay, Ana M., Lavín, José Luis, Beraza, Naiara, Perugorria, María J., Banales, Jesus M., Villa, Erica, Fraga, Mario F., Anguita, Juan, Avila, Matias A., Berasain, Carmen, Iruzibieta, Paula, Crespo, Javier, Lu, Shelly C., Varela-Rey, Marta, Mato, José M., Delgado, Teresa C., Martínez-Chantar, María L.
Publicado 2018