Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status

por Chen, Sizhuo, Zhou, Mengqi, Dong, Aiping, Loppnau, Peter, Wang, Min, Min, Jinrong, Liu, Ke
Publicado 2021

Structural Basis of the Chromodomain of Cbx3 Bound to Methylated Peptides from Histone H1 and G9a

por Ruan, Jianbin, Ouyang, Hui, Amaya, Maria F., Ravichandran, Mani, Loppnau, Peter, Min, Jinrong, Zang, Jianye
Publicado 2012

Structural basis for substrate recognition by the human N-terminal methyltransferase 1

por Dong, Cheng, Mao, Yunfei, Tempel, Wolfram, Qin, Su, Li, Li, Loppnau, Peter, Huang, Rong, Min, Jinrong
Publicado 2015

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

por Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Publicado 2016

Structural and functional analysis of the DOT1L–AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis

por Zhang, Heng, Zhou, Bo, Qin, Su, Xu, Jing, Harding, Rachel, Tempel, Wolfram, Nayak, Vinod, Li, Yanjun, Loppnau, Peter, Dou, Yali, Min, Jinrong
Publicado 2018

Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4

por Liu, Yanli, Qin, Su, Chen, Tsai-Yu, Lei, Ming, Dhar, Shilpa S., Ho, Jolene Caifeng, Dong, Aiping, Loppnau, Peter, Li, Yanjun, Lee, Min Gyu, Min, Jinrong
Publicado 2019

Correction: Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

por Allali-Hassani, Abdellah, Pan, Wang, Dombrovski, Ludmila, Najmanovich, Rafi, Tempel, Wolfram, Dong, Aiping, Loppnau, Peter, Martin, Fernando, Thornton, Janet, Edwards, Aled, Bochkarev, Alexey, Plotnikov, Alexander, Vedadi, Masoud, Arrowsmith, Cheryl
Publicado 2007

Structural and Chemical Profiling of the Human Cytosolic Sulfotransferases

por Allali-Hassani, Abdellah, Pan, Patricia W, Dombrovski, Ludmila, Najmanovich, Rafael, Tempel, Wolfram, Dong, Aiping, Loppnau, Peter, Martin, Fernando, Thonton, Janet, Edwards, Aled M, Bochkarev, Alexey, Plotnikov, Alexander N, Vedadi, Masoud, Arrowsmith, Cheryl H
Publicado 2007

SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses

por Li, Fengling, Ghiabi, Pegah, Hajian, Taraneh, Klima, Martin, Li, Alice Shi Ming, Khalili Yazdi, Aliakbar, Chau, Irene, Loppnau, Peter, Kutera, Maria, Seitova, Almagul, Bolotokova, Albina, Hutchinson, Ashley, Perveen, Sumera, Boura, Evzen, Vedadi, Masoud
Publicado 2023

H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1

por Jurkowska, Renata Z., Qin, Su, Kungulovski, Goran, Tempel, Wolfram, Liu, Yanli, Bashtrykov, Pavel, Stiefelmaier, Judith, Jurkowski, Tomasz P., Kudithipudi, Srikanth, Weirich, Sara, Tamas, Raluca, Wu, Hong, Dombrovski, Ludmila, Loppnau, Peter, Reinhardt, Richard, Min, Jinrong, Jeltsch, Albert
Publicado 2017

Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation

por El Bakkouri, Majida, Kouidmi, Imène, Wernimont, Amy K., Amani, Mehrnaz, Hutchinson, Ashley, Loppnau, Peter, Kim, Jeong Joo, Flueck, Christian, Walker, John R., Seitova, Alma, Senisterra, Guillermo, Kakihara, Yoshito, Kim, Choel, Blackman, Michael J., Calmettes, Charles, Baker, David A., Hui, Raymond
Publicado 2019

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

por Devkota, Kanchan, Schapira, Matthieu, Perveen, Sumera, Khalili Yazdi, Aliakbar, Li, Fengling, Chau, Irene, Ghiabi, Pegah, Hajian, Taraneh, Loppnau, Peter, Bolotokova, Albina, Satchell, Karla J.F., Wang, Ke, Li, Deyao, Liu, Jing, Smil, David, Luo, Minkui, Jin, Jian, Fish, Paul V., Brown, Peter J., Vedadi, Masoud
Publicado 2021

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II

por Liu, Yanli, Iqbal, Aman, Li, Weiguo, Ni, Zuyao, Wang, Yalong, Ramprasad, Jurupula, Abraham, Karan Joshua, Zhang, Mengmeng, Zhao, Dorothy Yanling, Qin, Su, Loppnau, Peter, Jiang, Honglv, Guo, Xinghua, Brown, Peter J., Zhen, Xuechu, Xu, Guoqiang, Mekhail, Karim, Ji, Xingyue, Bedford, Mark T., Greenblatt, Jack F., Min, Jinrong
Publicado 2022

Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins

por Zhong, Nan, Loppnau, Peter, Seitova, Alma, Ravichandran, Mani, Fenner, Maria, Jain, Harshika, Bhattacharya, Anandi, Hutchinson, Ashley, Paduch, Marcin, Lu, Vincent, Olszewski, Michal, Kossiakoff, Anthony A., Dowdell, Evan, Koide, Akiko, Koide, Shohei, Huang, Haiming, Nadeem, Vincent, Sidhu, Sachdev S., Greenblatt, Jack F., Marcon, Edyta, Arrowsmith, Cheryl H., Edwards, Aled M., Gräslund, Susanne
Publicado 2015

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

por Harding, Rachel J., Deme, Justin C., Hevler, Johannes F., Tamara, Sem, Lemak, Alexander, Cantle, Jeffrey P., Szewczyk, Magdalena M., Begeja, Nola, Goss, Siobhan, Zuo, Xiaobing, Loppnau, Peter, Seitova, Alma, Hutchinson, Ashley, Fan, Lixin, Truant, Ray, Schapira, Matthieu, Carroll, Jeffrey B., Heck, Albert J. R., Lea, Susan M., Arrowsmith, Cheryl H.
Publicado 2021

RPRD1A and RPRD1B Are Human RNA Polymerase II C-Terminal Domain Scaffolds for Ser5 Dephosphorylation

por Ni, Zuyao, Xu, Chao, Guo, Xinghua, Hunter, Gerald O., Kuznetsova, Olga V., Tempel, Wolfram, Marcon, Edyta, Zhong, Guoqing, Guo, Hongbo, Kuo, Wei-Hung William, Li, Joyce, Young, Peter, Olsen, Jonathan B., Wan, Cuihong, Loppnau, Peter, El Bakkouri, Majida, Senisterra, Guillermo A., He, Hao, Huang, Haiming, Sidhu, Sachdev S., Emili, Andrew, Murphy, Shona, Mosley, Amber L., Arrowsmith, Cheryl H., Min, Jinrong, Greenblatt, Jack F.
Publicado 2014

Epitope-specific antibody responses differentiate COVID-19 outcomes and variants of concern

por Voss, Courtney, Esmail, Sally, Liu, Xuguang, Knauer, Michael J., Ackloo, Suzanne, Kaneko, Tomonori, Lowes, Lori, Stogios, Peter, Seitova, Almagul, Hutchinson, Ashley, Yusifov, Farhad, Skarina, Tatiana, Evdokimova, Elena, Loppnau, Peter, Ghiabi, Pegah, Haijan, Taraneh, Zhong, Shanshan, Abdoh, Husam, Hedley, Benjamin D., Bhayana, Vipin, Martin, Claudio M., Slessarev, Marat, Chin-Yee, Benjamin, Fraser, Douglas D., Chin-Yee, Ian, Li, Shawn S.C.
Publicado 2021

Discovery of a chemical probe for PRDM9

por Allali-Hassani, Abdellah, Szewczyk, Magdalena M., Ivanochko, Danton, Organ, Shawna L., Bok, Jabez, Ho, Jessica Sook Yuin, Gay, Florence P. H., Li, Fengling, Blazer, Levi, Eram, Mohammad S., Halabelian, Levon, Dilworth, David, Luciani, Genna M., Lima-Fernandes, Evelyne, Wu, Qin, Loppnau, Peter, Palmer, Nathan, Talib, S. Zakiah A., Brown, Peter J., Schapira, Matthieu, Kaldis, Philipp, O’Hagan, Ronan C., Guccione, Ernesto, Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Sanders, John M., Kattar, Solomon D., Bennett, D. Jonathan, Nicholson, Benjamin, Vedadi, Masoud
Publicado 2019

Target highlights in CASP13: Experimental target structures through the eyes of their authors

por Lepore, Rosalba, Kryshtafovych, Andriy, Alahuhta, Markus, Veraszto, Harshul A., Bomble, Yannick J., Bufton, Joshua C., Bullock, Alex N., Caba, Cody, Cao, Hongnan, Davies, Owen R., Desfosses, Ambroise, Dunne, Matthew, Fidelis, Krzysztof, Goulding, Celia W., Gurusaran, Manickam, Gutsche, Irina, Harding, Christopher J., Hartmann, Marcus D., Hayes, Christopher S., Joachimiak, Andrzej, Leiman, Petr G., Loppnau, Peter, Lovering, Andrew L., Lunin, Vladimir V., Michalska, Karolina, Mir‐Sanchis, Ignacio, Mitra, AK, Moult, John, Phillips Jr, George N., Pinkas, Daniel M., Rice, Phoebe A., Tong, Yufeng, Topf, Maya, Walton, Jonathan D., Schwede, Torsten
Publicado 2019