Editing TINF2 as a potential therapeutic approach to restore telomere length in dyskeratosis congenita

por Choo, Seunga, Lorbeer, Franziska K., Regalado, Samuel G., Short, Sarah B., Wu, Shannon, Rieser, Gabrielle, Bertuch, Alison A., Hockemeyer, Dirk
Publicado 2022

Transient activation of the UPR(ER) is an essential step in the acquisition of pluripotency during reprogramming

por Simic, Milos S., Moehle, Erica A., Schinzel, Robert T., Lorbeer, Franziska K., Halloran, Jonathan J., Heydari, Kartoosh, Sanchez, Melissa, Jullié, Damien, Hockemeyer, Dirk, Dillin, Andrew
Publicado 2019

Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides

por Birsoy, Kıvanç, Possemato, Richard, Lorbeer, Franziska K., Bayraktar, Erol C., Thiru, Prathapan, Yucel, Burcu, Wang, Tim, Chen, Walter W., Clish, Clary B., Sabatini, David M.
Publicado 2014

Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System

por Rodrigues, Gonçalo M.C., Gaj, Thomas, Adil, Maroof M., Wahba, Joyce, Rao, Antara T., Lorbeer, Franziska K., Kulkarni, Rishi U., Diogo, Maria Margarida, Cabral, Joaquim M.S., Miller, Evan W., Hockemeyer, Dirk, Schaffer, David V.
Publicado 2017

TINF2 is a haploinsufficient tumor suppressor that limits telomere length

por Schmutz, Isabelle, Mensenkamp, Arjen R, Takai, Kaori K, Haadsma, Maaike, Spruijt, Liesbeth, de Voer, Richarda M, Choo, Seunga Sara, Lorbeer, Franziska K, van Grinsven, Emma J, Hockemeyer, Dirk, Jongmans, Marjolijn CJ, de Lange, Titia
Publicado 2020

A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma

por Kebir, Sied, Ullrich, Vivien, Berger, Pia, Dobersalske, Celia, Langer, Sarah, Rauschenbach, Laurèl, Trageser, Daniel, Till, Andreas, Lorbeer, Franziska K., Wieland, Anja, Wilhelm-Buchstab, Timo, Ahmad, Ashar, Fröhlich, Holger, Cima, Igor, Prasad, Shruthi, Matschke, Johann, Jendrossek, Verena, Remke, Marc, Grüner, Barbara M., Roesch, Alexander, Siveke, Jens T., Herold-Mende, Christel, Blau, Tobias, Keyvani, Kathy, van Landeghem, Frank K.H., Pietsch, Torsten, Felsberg, Jörg, Reifenberger, Guido, Weller, Michael, Sure, Ulrich, Brüstle, Oliver, Simon, Matthias, Glas, Martin, Scheffler, Björn
Publicado 2023

The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation

por Kosti, Adam, de Araujo, Patricia Rosa, Li, Wei-Qing, Guardia, Gabriela D. A., Chiou, Jennifer, Yi, Caihong, Ray, Debashish, Meliso, Fabiana, Li, Yi-Ming, Delambre, Talia, Qiao, Mei, Burns, Suzanne S., Lorbeer, Franziska K., Georgi, Fanny, Flosbach, Markus, Klinnert, Sarah, Jenseit, Anne, Lei, Xiufen, Sandoval, Carolina Romero, Ha, Kevin, Zheng, Hong, Pandey, Renu, Gruslova, Aleksandra, Gupta, Yogesh K., Brenner, Andrew, Kokovay, Erzsebet, Hughes, Timothy R., Morris, Quaid D., Galante, Pedro A. F., Tiziani, Stefano, Penalva, Luiz O. F.
Publicado 2020