MqsR is a noncanonical microbial RNase toxin that is inhibited by antitoxin MqsA via steric blockage of substrate binding

por Yu, Victor, Ronzone, Erik, Lord, Dana, Peti, Wolfgang, Page, Rebecca
Publicado 2022

BdcA, a Protein Important for Escherichia coli Biofilm Dispersal, Is a Short-Chain Dehydrogenase/Reductase that Binds Specifically to NADPH

por Lord, Dana M., Baran, Ayse Uzgoren, Wood, Thomas K., Peti, Wolfgang, Page, Rebecca
Publicado 2014

A peculiar IclR family transcription factor regulates para-hydroxybenzoate catabolism in Streptomyces coelicolor

por Zhang, Rui, Lord, Dana M, Bajaj, Rakhi, Peti, Wolfgang, Page, Rebecca, Sello, Jason K
Publicado 2018

McbR/YncC: Implications for the Mechanism of Ligand and DNA Binding by a Bacterial GntR Transcriptional Regulator Involved in Biofilm Formation

por Lord, Dana M., Uzgoren Baran, Ayse, Soo, Valerie W. C., Wood, Thomas K., Peti, Wolfgang, Page, Rebecca
Publicado 2014

Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody

por Lord, Dana M., Bird, Julie J., Honey, Denise M., Best, Annie, Park, Anna, Wei, Ronnie R., Qiu, Huawei
Publicado 2018

A Novel Type V TA System Where mRNA for Toxin GhoT is Cleaved by Antitoxin GhoS

por Wang, Xiaoxue, Lord, Dana M., Cheng, Hsin-Yao, Osbourne, Devon O., Hong, Seok Hoon, Sanchez-Torres, Viviana, Quiroga, Cecilia, Zheng, Kevin, Herrmann, Torsten, Peti, Wolfgang, Benedik, Michael J., Page, Rebecca, Wood, Thomas K.
Publicado 2012

A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms

por Stefano, James E., Lord, Dana M., Zhou, Yanfeng, Jaworski, Julie, Hopke, Joern, Travaline, Tara, Zhang, Ningning, Wong, Karen, Lennon, Amanda, He, Timothy, Bric-Furlong, Eva, Cherrie, Cornishia, Magnay, Tristan, Remy, Elisabeth, Brondyk, William, Qiu, Huawei, Radošević, Katarina
Publicado 2021

Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific

por Ramasubramanian, Anusuya, Tennyson, Rachel, Magnay, Maureen, Kathuria, Sagar, Travaline, Tara, Jain, Annu, Lord, Dana M., Salemi, Megan, Sullivan, Caitlin, Magnay, Tristan, Hu, Jiali, Bric-Furlong, Eva, Rival, Pierrick, Zhou, Yanfeng, Hoffmann, Dietmar, Brondyk, William, Radošević, Katarina, Chowdhury, Partha S.
Publicado 2020

1348. Identification of GB-0669, a Novel S-2 Targeted Spike Monoclonal Antibody in Development for SARS-CoV-2 Prophylaxis

por Borriello, Francesco, Marden, Grace, Li, Hongru, Carlin, Eric, Sharma, Geetika, Menzenski, Monica, Jecrois, Anne, Palovcak, Eugene, Lord, Dana, Tao, Jenhan, Grigoryan, Gevorg, Root, Adam, Hopson, Kristen, Hazuda, Daria, Van Epps, Heather A, Ramos, Alex, Joh, Nathan H, Russell, Pamela, Garlick, Joseph D
Publicado 2023

Illuminating protein space with a programmable generative model

por Ingraham, John B., Baranov, Max, Costello, Zak, Barber, Karl W., Wang, Wujie, Ismail, Ahmed, Frappier, Vincent, Lord, Dana M., Ng-Thow-Hing, Christopher, Van Vlack, Erik R., Tie, Shan, Xue, Vincent, Cowles, Sarah C., Leung, Alan, Rodrigues, João V., Morales-Perez, Claudio L., Ayoub, Alex M., Green, Robin, Puentes, Katherine, Oplinger, Frank, Panwar, Nishant V., Obermeyer, Fritz, Root, Adam R., Beam, Andrew L., Poelwijk, Frank J., Grigoryan, Gevorg
Publicado 2023